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Development of new diagnostic method and therapy for endoleak after aortic stent implantation

Research Project

Project/Area Number 17K10446
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeMulti-year Fund
Section一般
Research Field Radiation science
Research InstitutionKyushu University

Principal Investigator

USHIJIMA YASUHIRO  九州大学, 大学病院, 助教 (40432934)

Co-Investigator(Kenkyū-buntansha) 浅山 良樹  九州大学, 医学研究院, 教授 (40380414)
西江 昭弘  九州大学, 医学研究院, 准教授 (20457427)
石神 康生  九州大学, 大学病院, 講師 (10403916)
藤田 展宏  九州大学, 大学病院, 助教 (30610612)
森田 孝一郎  九州大学, 大学病院, 医員 (20725858)
石松 慶祐  九州大学, 大学病院, 医員 (20800147)
馬場 眞吾  九州大学, 大学病院, 准教授 (80380450)
本田 浩  九州大学, 大学病院, 教授 (90145433)
高尾 誠一朗  九州大学, 大学病院, 医員 (70803443)
Project Period (FY) 2017-04-01 – 2020-03-31
Project Status Completed (Fiscal Year 2019)
Budget Amount *help
¥3,640,000 (Direct Cost: ¥2,800,000、Indirect Cost: ¥840,000)
Fiscal Year 2019: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2018: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2017: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
Keywords超音波造影剤 / CT angiography / 塞栓術 / テーラーメード医療 / エンドリーク / マルチモダリティ
Outline of Final Research Achievements

Using various imaging modalities such as CT and ultrasonography, we optimized the diagnosis and detection of endoleak after aortic stent implantation. In particular, even in patients with impaired renal function, sufficient evaluation can be performed while reducing the burden of the contrast medium.
Regarding the treatment method, it was clarified that embolization by direct percutaneous puncture can be performed with a short-time procedure and a small amount of contrast medium, and it seems to be an effective treatment for endoleak.

Academic Significance and Societal Importance of the Research Achievements

低侵襲な医療が求められている現在において、従来の大動脈ステント留置後のエンドリークに対する診断法および治療法を、より低量の造影剤や短時間の手技で行うことができることを明らかにした。腎機能低下患者への適応拡大や患者への身体的な負担軽減のみならず、ひいては医療費抑制にも貢献できる可能性があり、これからの高齢化社会に十分適応できるものと考えられる。

Report

(4 results)
  • 2019 Annual Research Report   Final Research Report ( PDF )
  • 2018 Research-status Report
  • 2017 Research-status Report
  • Research Products

    (3 results)

All 2020 2018 2017

All Journal Article (1 results) (of which Peer Reviewed: 1 results,  Open Access: 1 results) Presentation (2 results)

  • [Journal Article] Safety and Efficacy of Embolization Using N-Butyl Cyanoacrylate via a Percutaneous Direct Approach for Endoleaks after Abdominal/Thoracic Endovascular Aortic Repair2020

    • Author(s)
      Yasuhiro Ushijima, Yoshiki Asayama, Akihiro Nishie, Kousei Ishigami, Yukihisa Takayama, Daisuke Okamoto, Nobuhiro Fujita, Koichiro Morita, Hiroshi Honda
    • Journal Title

      Interventional Radiology

      Volume: 5 Issue: 1 Pages: 1-9

    • DOI

      10.22575/interventionalradiology.2018-0018

    • NAID

      130007803376

    • ISSN
      2432-0935
    • Year and Date
      2020-02-28
    • Related Report
      2019 Annual Research Report
    • Peer Reviewed / Open Access
  • [Presentation] Percutaneous transabdominal approach for the treatment of Type II endoleaks after EVAR of AAA2018

    • Author(s)
      高尾誠一郎、浅山良樹、牛島泰宏、森田孝一郎
    • Organizer
      第47回日本IVR学会
    • Related Report
      2018 Research-status Report
  • [Presentation] EVAR後typeⅡendoleakに対し経皮経腹的直接穿刺による塞栓術を施行した1例2017

    • Author(s)
      高尾誠一郎、浅山良樹、牛島泰宏、森田孝一郎
    • Organizer
      第40回九州IVR研究会
    • Related Report
      2017 Research-status Report

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Published: 2017-04-28   Modified: 2021-02-19  

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