The development of the vascular endothelial cell-coated dacron sheet preceding the narrow graft to utilize coronary artery bypass grafting

• Project/Area Number: 17K10737
• Research Category: Grant-in-Aid for Scientific Research (C)
• Allocation Type: Multi-year Fund
• Section: 一般
• Research Field: Cardiovascular surgery
• Research Institution: Jichi Medical University (2021); Gunma Institute of Public Health and Environmental Sciences (2017-2020)
• Principal Investigator: Hayashi Hidenori 自治医科大学, 医学部, 助教 (30648788)
• Co-Investigator(Kenkyū-buntansha): 金子 政弘 和歌山県立医科大学, 医学部, 助教 (40433346) ; 吉増 達也 和歌山県立医科大学, 医学部, 准教授 (60316099) ; 西村 好晴 和歌山県立医科大学, 医学部, 教授 (70254539) ; 畑田 充俊 和歌山県立医科大学, 医学部, 博士研究員 (70508027)
• Project Period (FY): 2017-04-01 – 2022-03-31
• Project Status: Completed (Fiscal Year 2021)
• Budget Amount: ¥4,550,000 (Direct Cost: ¥3,500,000、Indirect Cost: ¥1,050,000); Fiscal Year 2020: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000); Fiscal Year 2019: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000); Fiscal Year 2018: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000); Fiscal Year 2017: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
• Keywords: 冠動脈バイパス術 / 小口径人工血管 / 血管内皮細胞 / 再生医療 / 小口径人口血管 / 人工血管 / CABG / 細胞外基質

Outline of Final Research Achievements

Our purpose was to develop the novel method to prepare the vascular endothelial cell-coated dacron sheet to precede the extremely narrow graft to utilize coronary artery bypass grafting. But we could not establish the technique. THerefore, we could not acheive the our aim.

Academic Significance and Societal Importance of the Research Achievements

本研究の目的が達成できれば、冠動脈バイパス術に使用可能な小口径人工血管の開発につながる可能性があったが、今回は当初の目的を達成することができなかった。