| Budget Amount *help |
¥4,550,000 (Direct Cost: ¥3,500,000、Indirect Cost: ¥1,050,000)
Fiscal Year 2019: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
Fiscal Year 2018: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2017: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
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| Outline of Final Research Achievements |
The effect of Vasohibin-2, an angiogenesis regulator, on the development and progression of abdominal aortic aneurysm was fundamentally examined. When abdominal aortic aneurysm was induced in each of the mice in which Vasohibin-2 was overexpressed and the control mice, no significant difference was observed in the onset and progress of abdominal aortic aneurysm between the two groups. To confirm the result, protein expression was examined by histological and molecular biological approachs, but similarly no significant difference was observed between the two groups. Taken together, we found that Vasohibin-2 does not affect the development nor progression of abdominal aortic aneurysm.
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