• Search Research Projects
  • Search Researchers
  • How to Use
  1. Back to previous page

Development of a new material to prevent postoperative adhesions following pulmonary resection

Research Project

Project/Area Number 17K10809
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeMulti-year Fund
Section一般
Research Field Respiratory surgery
Research InstitutionKyoto University

Principal Investigator

Hamaji Masatsugu  京都大学, 医学研究科, 講師 (70782142)

Co-Investigator(Kenkyū-buntansha) 伊達 洋至  京都大学, 医学研究科, 教授 (60252962)
Project Period (FY) 2017-04-01 – 2020-03-31
Project Status Completed (Fiscal Year 2019)
Budget Amount *help
¥4,550,000 (Direct Cost: ¥3,500,000、Indirect Cost: ¥1,050,000)
Fiscal Year 2019: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2018: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Fiscal Year 2017: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Keywords開胸 / 術後癒着 / 肺門部 / 癒着防止 / 吸収性素材 / 術後合併症 / 新素材 / 癒着予防
Outline of Final Research Achievements

In canine models, using adult Beagle dogs, right thoracotomy and right upper lobectomy was performed (the upper lobe branched of pulmonary artery, pulmonary vein, and bronchus were ligated and divided using silk ties). We applied a bioabsorbable sheet composed of polyglycolic acid on the hilum, resulting in no improvement in postoperative adhesion. Then we applied "Adspray", which is commercially available, resulting a similar adhesion. Also we applied bioabsorbable sheet composed of oxidized cellulose, without significant effects on postoperative adhesion.

Academic Significance and Societal Importance of the Research Achievements

腹部手術において使用されている癒着防止材は、胸部手術特に肺切除術後の、肺門部における術後癒着防止にはほとんど効果が見られなかった。同じ整体吸収性素材でも、腹部における分解に要する時間と胸部において分解に要する時間は異なる、ということが推測されたため、腹部で使用されている素材とは全く異なる素材の開発が必要と考えられた。

Report

(4 results)
  • 2019 Annual Research Report   Final Research Report ( PDF )
  • 2018 Research-status Report
  • 2017 Research-status Report
  • Research Products

    (1 results)

All Other

All Remarks (1 results)

  • [Remarks] 京都大学呼吸器外科

    • URL

      https://www.thoracic-kyoto-u.gr.jp

    • Related Report
      2017 Research-status Report

URL: 

Published: 2017-04-28   Modified: 2021-02-19  

Information User Guide FAQ News Terms of Use Attribution of KAKENHI

Powered by NII kakenhi