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Basic research on the development of magnetic resonance imaging guided passive catheterization

Research Project

Project/Area Number 17K10897
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeMulti-year Fund
Section一般
Research Field Neurosurgery
Research InstitutionKobe University

Principal Investigator

Fujita Atsushi  神戸大学, 医学部附属病院, 講師 (60379360)

Project Period (FY) 2017-04-01 – 2020-03-31
Project Status Completed (Fiscal Year 2019)
Budget Amount *help
¥2,860,000 (Direct Cost: ¥2,200,000、Indirect Cost: ¥660,000)
Fiscal Year 2019: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2018: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2017: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Keywords磁気共鳴画像 / 低侵襲治療 / カテーテル治療 / カテーテル / 磁気共鳴画像支援 / 血管内治療 / 被爆 / 放射線被爆 / 放射線治療
Outline of Final Research Achievements

In order to realize the minimally invasive neurointervention without radiation exposure, we conducted a basic study of a passive catheterization by magnetic resonance imaging (MRI). We studied optimal imaging protocols of MRI for visualized and guide a special catheter equipped with a microcoil at tip to the target blood vessel without using fluoroscopy and evaluated the heat generation of the coil. The heat generation of the catheter could be minimized by using the gradient echo sequence with acceptable contrast-noise ratio. Our study showed that specially designed catheters could be visualized and tracked in real time and treatment with catheters could be safely performed.

Academic Significance and Societal Importance of the Research Achievements

我々の研究により血管内治療を行うには不可避であった被爆を減らすことが出来る可能性を示すことができ,今後の低侵襲治療の広がりに貢献できる可能性を示した.これまで大血管に限ってなされて来た研究分野をより細い血管である中枢神経系の治療にまで広げたという意義は大きい.また,磁気共鳴画像による高速撮影の研究開発は,血管内治療時におけるX線透視画像の代用となるだけでなく,通常の診断撮影においても検査時間の短縮という点で医療に貢献できると考える.

Report

(4 results)
  • 2019 Annual Research Report   Final Research Report ( PDF )
  • 2018 Research-status Report
  • 2017 Research-status Report
  • Research Products

    (3 results)

All 2020 2019

All Journal Article (3 results) (of which Peer Reviewed: 3 results)

  • [Journal Article] Ultrasonographically-guided stent placement at the vertebral artery origin without contrast medium: A case report2020

    • Author(s)
      Kohta Masaaki、Fujita Atsushi、Yamashita Shunsuke、Imanishi Takamitsu、Kohmura Eiji
    • Journal Title

      Journal of Clinical Ultrasound

      Volume: - Issue: 6 Pages: 362-366

    • DOI

      10.1002/jcu.22839

    • NAID

      120006993641

    • Related Report
      2019 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Impact of transvenous embolization via superior ophthalmic vein on reducing the total number of coils used for patients with cavernous sinus dural arteriovenous fistula2019

    • Author(s)
      Fujita Atsushi、Kohta Masaaki、Sasayama Takashi、Kohmura Eiji
    • Journal Title

      Neurosurgical Review

      Volume: - Issue: 1 Pages: 401-409

    • DOI

      10.1007/s10143-019-01227-9

    • NAID

      120006975815

    • Related Report
      2019 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Pencil Beam Presaturation Magnetic Resonance Imaging Helps to Identify Patients at Risk for Intolerance to Temporary Internal Carotid Artery Occlusion During Carotid Endarterectomy and Carotid Artery Stenting2019

    • Author(s)
      Tanaka Jun、Hosoda Kohkichi、Matsuo Kazuya、Kyotani Katsusuke、Takemoto Youta、Yamamoto Yusuke、Fujita Atsushi、Kohta Masaaki、Kimura Hidehito、Sasayama Takashi、Kohmura Eiji
    • Journal Title

      World Neurosurgery

      Volume: 130 Pages: e899-e907

    • DOI

      10.1016/j.wneu.2019.07.033

    • NAID

      120006993678

    • Related Report
      2019 Annual Research Report
    • Peer Reviewed

URL: 

Published: 2017-04-28   Modified: 2021-02-19  

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