Investigation of ocular blood flow in eyes with retinal disease by comparison with normal eye database

• Project/Area Number: 17K11421
• Research Category: Grant-in-Aid for Scientific Research (C)
• Allocation Type: Multi-year Fund
• Section: 一般
• Research Field: Ophthalmology
• Research Institution: Akita University (2019); Nagoya University (2017-2018)
• Principal Investigator: Iwase Takeshi 秋田大学, 医学系研究科, 教授 (80642339)
• Project Period (FY): 2017-04-01 – 2020-03-31
• Project Status: Completed (Fiscal Year 2019)
• Budget Amount: ¥4,680,000 (Direct Cost: ¥3,600,000、Indirect Cost: ¥1,080,000); Fiscal Year 2019: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000); Fiscal Year 2018: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000); Fiscal Year 2017: ¥2,210,000 (Direct Cost: ¥1,700,000、Indirect Cost: ¥510,000)
• Keywords: 眼血流 / 網脈絡膜 / 糖尿病網膜症 / 網膜剥離 / 緑内障 / 眼循環 / 自己調節機能 / 網膜疾患 / 眼血流動態

Outline of Final Research Achievements

In the change of ocular blood flow for intraocular pressure elevation, it has been found that the optic nerve head has a strong autoregulation for maintaining the blood flow to the retina constant and the choroid has a weak autoregulation which results in significant correlation between the luminal area and blood flow.
It has been found that retinal and choroidal blood flow is reduced with time after pan retinal photocoagulation and the reduction is less in using pattern scan photocoagulation than that in using the conventional photocoagulation.
I already found the sex-related differences in ocular blood flow and have elucidated the mechanism during this period. It is concluded that the sex-related differences in the hemoglobin level and the negative correlation between hemoglobin and the ocular blood flow are the causes of the sex-related differences in the ocular blood flow.

Academic Significance and Societal Importance of the Research Achievements

日本における失明原因の上位である緑内障や糖尿病網膜症について，眼血流の観点から研究を進めた．
緑内障では視野欠損が生じるという機能的変化よりも神経線維層の脱落という構造的変化が先んじて生じること，および機能的変化が収束してもその後に血流変化が生じることを突き止めた．このことから，緑内障の早期発見には構造的変化，後期の経過を診る上では血流変化に注意することが重要であることを解明した．
また糖尿病網膜症に対する加療としての網膜光凝固では，パターンスキャンレーザーで行なった方が有意に通常の光凝固よりも経時的な血流低下が少ないことを見出した．

Research Products

• [Journal Article] Correlation between blood flow on optic nerve head and structural and functional changes in eyes with glaucoma (2020)
  • Author(s): Kuroda Fumi、Iwase Takeshi、Yamamoto Kentaro、Ra Eimei、Terasaki Hiroko
  • Journal Title: Scientific Reports Volume: 10 Issue: 1 Pages: 729-729
  • DOI: 10.1038/s41598-020-57583-w
  • Peer Reviewed / Open Access
• [Journal Article] Correlations between intraretinal cystoid cavities and pre- and postoperative characteristics of eyes after closure of idiopathic macular hole (2020)
  • Author(s): Goto Kensuke、Iwase Takeshi、Yamamoto Kentaro、Ra Eimei、Terasaki Hiroko
  • Journal Title: Scientific Reports Volume: 10 Issue: 1 Pages: 2310-2310
  • DOI: 10.1038/s41598-020-59295-7
  • Peer Reviewed / Open Access
• [Journal Article] Retinal Degeneration After Accidental Intravitreal Injection of Ropivacaine During Strabismus Surgery (2019)
  • Author(s): Iwase Takeshi、Ra Eimei、Terasaki Hiroko
  • Journal Title: Retina Volume: 39 Issue: 7 Pages: e30-e31
  • DOI: 10.1097/iae.0000000000002587
  • Peer Reviewed
• [Journal Article] Evaluation of blood flow on optic nerve head after pattern scan and conventional laser panretinal photocoagulation (2019)
  • Author(s): Iwase Takeshi、Mikoshiba Yuji、Ra Eimei、Yamamoto Kentaro、Ueno Yoshitaka、Terasaki Hiroko
  • Journal Title: Medicine Volume: 98 Issue: 24 Pages: e16062-e16062
  • DOI: 10.1097/md.0000000000016062
  • Peer Reviewed / Open Access
• [Journal Article] New Technique to Drain Suprachoroidal Fluid With a 27-Gauge Needle During Vitrectomy (2019)
  • Author(s): Iwase Takeshi、Ra Eimei、Terasaki Hiroko
  • Journal Title: Retina Volume: 39 Issue: 10 Pages: 1-1
  • DOI: 10.1097/iae.0000000000002594
  • Peer Reviewed / Open Access
• [Journal Article] Influence of submacular fluid on recovery of retinal function and structure after successful rhegmatogenous retinal reattachment (2019)
  • Author(s): Kobayashi Misato、Iwase Takeshi、Yamamoto Kentaro、Ra Eimei、Hirata Norifumi、Terasaki Hiroko
  • Journal Title: PLOS ONE Volume: 14 Issue: 7 Pages: e0218216-e0218216
  • DOI: 10.1371/journal.pone.0218216
  • Peer Reviewed / Open Access
• [Journal Article] Correlation between macular vessel density and number of intravitreal anti-VEGF agents for macular edema associated with branch retinal vein occlusion (2019)
  • Author(s): Tomita Ryo、Iwase Takeshi、Goto Kensuke、Yamamoto Kentaro、Ra Eimei、Terasaki Hiroko
  • Journal Title: Scientific Reports Volume: 9 Issue: 1 Pages: 16388-16388
  • DOI: 10.1038/s41598-019-52732-2
  • NAID: 120007172090
  • Peer Reviewed / Open Access
• [Journal Article] Japan-Retinal Detachment Registry Report I: preoperative findings in eyes with primary retinal detachment. (2019)
  • Author(s): Sakamoto T、Kawano S、Kawasaki R、Hirakata A、Yamashita H、Yamamoto S、Ishibashi T、and members of the J-RD Registry group.
  • Journal Title: Jpn J Ophthalmol Volume: 64 Issue: 1 Pages: 1-12
  • DOI: 10.1007/s10384-019-00702-6
  • Peer Reviewed
• [Journal Article] Choroidal and retinal displacements after vitrectomy with internal limiting membrane peeling in eyes with idiopathic macular hole (2019)
  • Author(s): Goto Kensuke、Iwase Takeshi、Akahori Tomohiko、Yamamoto Kentaro、Ra Eimei、Terasaki Hiroko
  • Journal Title: Scientific Reports Volume: 9 Issue: 1 Pages: 17568-17568
  • DOI: 10.1038/s41598-019-54106-0
  • NAID: 120007172089
  • Peer Reviewed / Open Access
• [Journal Article] RELATIONSHIP BETWEEN ABNORMALITIES OF PHOTORECEPTOR MICROSTRUCTURES AND MICROVASCULAR STRUCTURES DETERMINED BY OPTICAL COHERENCE TOMOGRAPHY ANGIOGRAPHY IN EYES WITH BRANCH RETINAL VEIN OCCLUSION. (2019)
  • Author(s): Ogasawara Y, Iwase T, Yamamoto K, Ra E, Terasaki H.
  • Journal Title: Retina Volume: - Issue: 2 Pages: 1-1
  • DOI: 10.1097/iae.0000000000002379
  • Peer Reviewed / Open Access
• [Journal Article] Multimodal Imaging in Bilateral Nature of the Choroidal Osteoma After Intraocular Inflammation Caused by Harada Disease (2019)
  • Author(s): Ozawa Kenji、Iwase Takeshi、Ito Yasuki、Onda Masahiro、Shiraki Ikumi、Kumada Mitsuki、Ito Rintaro、Mochizuki Kiyofumi
  • Journal Title: Retina Volume: 39 Issue: 9 Pages: e40-e41
  • DOI: 10.1097/iae.0000000000002611
  • Peer Reviewed
• [Journal Article] INNER MACULAR CHANGES AFTER VITRECTOMY WITH INTERNAL LIMITING MEMBRANE PEELING FOR RHEGMATOGENOUS RETINAL DETACHMENT: Similarity With Alport Syndrome. (2019)
  • Author(s): Fukukita H, Ito Y, Iwase T, Kaneko H, Yasuda S, Kataoka K, Terasaki H.
  • Journal Title: Retina Volume: - Issue: 12 Pages: 2332-2340
  • DOI: 10.1097/iae.0000000000002310
  • Peer Reviewed
• [Journal Article] Effect of intravitreal or sub-tenon triamcinolone acetonide injection at completion of vitrectomy on peripheral retinochoroidal thickness in eyes with proliferative diabetic retinopathy. (2019)
  • Author(s): Fujiwara Y, Iwase T, Yamamoto K, Ueno Y, Ra E, Terasaki H.
  • Journal Title: Sci Rep Volume: 9 Issue: 1 Pages: 171-171
  • DOI: 10.1038/s41598-018-37220-3
  • Peer Reviewed / Open Access
• [Journal Article] Correlation between preoperative factors and final visual acuity after successful rhegmatogenous retinal reattachment. (2019)
  • Author(s): Hirata N, Iwase T, Kobayashi M, Yamamoto K, Ra E, Terasaki H.
  • Journal Title: Sci Rep Volume: 9 Issue: 1 Pages: 3217-3217
  • DOI: 10.1038/s41598-019-39839-2
  • Peer Reviewed / Open Access
• [Journal Article] Biological Characteristics of Subsilicone Oil Fluid and Differences With Other Ocular Humors. (2019)
  • Author(s): Shimizu H, Kaneko H, Suzumura A, Takayama K, Namba R, Funahashi Y, Kataoka K, Iwase T, Hwang SJ, Ito S, Yamada K, Ueno S, Ito Y, Terasaki H.
  • Journal Title: Transl Vis Sci Technol Volume: 8 Issue: 1 Pages: 28-28
  • DOI: 10.1167/tvst.8.1.28
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] Macular displacement after vitrectomy in eyes with idiopathic macular hole determined by optical coherence tomography angiography. (2018)
  • Author(s): Akahori T, Iwase T, Yamamoto K, Ra E, Kawano K, Ito Y, Terasaki H.
  • Journal Title: Am J Ophthalmol Volume: 0 Pages: 0-0
  • DOI: 10.1016/j.ajo.2018.02.021
  • NAID: 120006496410
  • Peer Reviewed
• [Journal Article] A randomized clinical trial evaluating choroidal blood flow and morphology after conventional and pattern scan laser panretinal photocoagulation. (2018)
  • Author(s): Mikoshiba Y, Iwase T, Ueno Y, Yamamoto K, Ra E, Terasaki H.
  • Journal Title: Sci Rep Volume: 8 Issue: 1 Pages: 14128-14128
  • DOI: 10.1038/s41598-018-32487-y
  • Peer Reviewed / Open Access
• [Journal Article] Novel Classification of Early-stage Systemic Hypertensive Changes in Human Retina Based on OCTA Measurement of Choriocapillaris. (2018)
  • Author(s): Takayama K, Kaneko H, Ito Y, Kataoka K, Iwase T, Yasuma T, Matsuura T, Tsunekawa T, Shimizu H, Suzumura A, Ra E, Akahori T, Terasaki H.
  • Journal Title: Sci Rep Volume: 8 Issue: 1 Pages: 15163-15163
  • DOI: 10.1038/s41598-018-33580-y
  • Peer Reviewed / Open Access
• [Journal Article] Changes in choriocapillaris and retinal morphology after laser photocoagulation by OCT angiography: A case report. (2018)
  • Author(s): Iwase T, Ueno Y, Ra E, Ito Y, Terasaki H.
  • Journal Title: Medicine Volume: 97 Issue: 46 Pages: e13278-e13278
  • DOI: 10.1097/md.0000000000013278
  • Peer Reviewed / Open Access
• [Journal Article] Evaluation of optic nerve head blood flow in response to increase of intraocular pressure. (2018)
  • Author(s): Iwase T, Akahori T, Yamamoto K, Ra E, Terasaki H.
  • Journal Title: Sci Rep Volume: 8 Issue: 1 Pages: 17235-17235
  • DOI: 10.1038/s41598-018-35683-y
  • Peer Reviewed / Open Access
• [Journal Article] Multiple Sub-Internal Limiting Membrane Hemorrhages With Double Ring Sign in Eyes With Valsalva Retinopathy (2018)
  • Author(s): Iwase Takeshi、Ra Eimei、Ito Yasuki、Terasaki Hiroko
  • Journal Title: Retina Volume: 38 Issue: 1 Pages: e1-e2
  • DOI: 10.1097/iae.0000000000001935
  • Peer Reviewed / Open Access
• [Journal Article] Long-term results after limited macular translocation surgery for wet age-related macular degeneration. (2017)
  • Author(s): Oshima H, Iwase T, Ishikawa K, Yamamoto K, Terasaki H.
  • Journal Title: PLoS One Volume: 23 Issue: 5 Pages: e0177241-e0177241
  • DOI: 10.1371/journal.pone.0177241
  • Peer Reviewed / Open Access
• [Journal Article] Cytokine profiling in the sub-silicone oil fluid after vitrectomy surgeries for refractory retinal diseases (2017)
  • Author(s): Kaneko Hiroki、Takayama Kei、Asami Tetsu、Ito Yasuki、Tsunekawa Taichi、Iwase Takeshi、Funahashi Yasuhito、Ueno Shinji、Nonobe Norie、Yasuda Shunsuke、Suzumura Ayana、Shimizu Hideyuki、Kimoto Reona、Hwang Shiang-Jyi、Terasaki Hiroko
  • Journal Title: Scientific Reports Volume: 7 Issue: 1 Pages: 2640-2640
  • DOI: 10.1038/s41598-017-03124-x
  • Peer Reviewed / Open Access
• [Journal Article] Increased Retinal Thinning after Combination of Internal Limiting Membrane Peeling and Silicone Oil Endotamponade in Proliferative Diabetic Retinopathy (2017)
  • Author(s): Kaneko Hiroki、Matsuura Toshiyuki、Takayama Kei、Ito Yasuki、Iwase Takeshi、Ueno Shinji、Nonobe Norie、Yasuda Shunsuke、Kataoka Keiko、Terasaki Hiroko
  • Journal Title: Ophthalmologica Volume: 238 Issue: 4 Pages: 226-235
  • DOI: 10.1159/000479482
  • Peer Reviewed / Open Access
• [Journal Article] Change in choroidal blood flow and choroidal morphology due to segmental scleral buckling in eyes with rhegmatogenous retinal detachment. (2017)
  • Author(s): Iwase T, Kobayashi M, Yamamoto K, Yanagida K, Ra E, Terasaki H.
  • Journal Title: Sci Rep Volume: 7 Issue: 1 Pages: 5997-5997
  • DOI: 10.1038/s41598-017-05126-1
  • Peer Reviewed / Open Access
• [Journal Article] Perioperative factors that are significantly correlated with final visual acuity in eyes after successful rhegmatogenous retinal detachment surgery. (2017)
  • Author(s): Kobayashi M, Iwase T, Yamamoto K, Ra E, Murotani K, Terasaki H.
  • Journal Title: PLoS One Volume: 12 Issue: 9 Pages: e0184783-e0184783
  • DOI: 10.1371/journal.pone.0184783
  • Peer Reviewed / Open Access
• [Journal Article] Changes in Choroidal Blood Flow and Morphology in Response to Increase in Intraocular Pressure. (2017)
  • Author(s): Akahori T, Iwase T, Yamamoto K, Ra E, Terasaki H.
  • Journal Title: Invest Ophthalmol Vis Sci Volume: 58 Issue: 12 Pages: 5076-5085
  • DOI: 10.1167/iovs.17-21745
  • Peer Reviewed / Open Access
• [Journal Article] Investigation of causes of sex-related differences in ocular blood flow in healthy eyes determined by laser speckle flowgraphy (2017)
  • Author(s): Iwase Takeshi、Yamamoto Kentaro、Yanagida Kosei、Ra Eimei、Ito Yasuki、Murotani Kenta、Terasaki Hiroko
  • Journal Title: Scientific Reports Volume: 7 Issue: 1 Pages: 13878-13878
  • DOI: 10.1038/s41598-017-14118-0
  • Peer Reviewed / Open Access
• [Journal Article] Diurnal variation of pulse waveform parameters determined by laser speckle flowgraphy on the optic nerve head in healthy subjects. (2017)
  • Author(s): Fukami M, Iwase T, Yamamoto K, Ra E, Murotani K, Terasaki H.
  • Journal Title: Medicine (Baltimore). 2017 Nov;96(44):e8312. doi: 10.1097/MD.0000000000008312. Volume: 96 Issue: 44 Pages: e8312-e8312
  • DOI: 10.1097/md.0000000000008312
  • Peer Reviewed / Open Access
• [Presentation] Relationship between abnormalities of retinal structures and vascular structures determined by optical coherence tomography angiography in eyes with branch retinal vein occlusion (2019)
  • Author(s): Takeshi Iwase, Yasunobu Ogasawara, Kentaro Yamamoto, Eimei Ra, Hiroko Terasaki.
  • Organizer: Association for Research in Vision and Ophthalmology
  • Int'l Joint Research
• [Presentation] Relationship between displacement and thickness change of retina after vitrectomy in MH eyes. (2019)
  • Author(s): Kensuke Goto, Takeshi Iwase, Tomohiko Akahori, Hiroko Terasaki.
  • Organizer: Association for Research in Vision and Ophthalmology
  • Int'l Joint Research
• [Presentation] Investigation of the number of intravitreal injections of the anti-VEGF agent using OCT angiography for macular edema due to retinal vein branch occlusion (2019)
  • Author(s): Ryo Tomita, Takeshi Iwase, Yasunobu Ogasawara, Shunichi Suwa, Hiroko Terasaki.
  • Organizer: Association for Research in Vision and Ophthalmology
  • Int'l Joint Research
• [Presentation] Association between the retinal vessel caliber and the ocular blood flow in diabetic retinopathy (2019)
  • Author(s): Yoshitaka Ueno, Takeshi Iwase, Ryo Tomita, Kensuke Goto, Hiroko Terasaki
  • Organizer: Association for Research in Vision and Ophthalmology
  • Int'l Joint Research
• [Presentation] 網膜静脈分枝閉塞症による黄斑浮腫治療後の中心窩無血管領域，形態変化と視力との関連 (2019)
  • Author(s): 岩瀬 剛，小笠原 康伸，冨田 遼，羅 英明，寺﨑 浩子
  • Organizer: 第123回日本眼科学会総会
• [Presentation] 特発性黄斑円孔における硝子体術前語での網膜厚変化の検討 (2019)
  • Author(s): 後藤健介，岩瀬 剛，赤堀友彦，寺崎浩子
  • Organizer: 第123回日本眼科学会総会
• [Presentation] 網膜静脈分枝閉塞症による黄斑浮腫への抗VEGF薬硝子体注射回数と関連する因子の検討 (2019)
  • Author(s): 冨田 遼，岩瀬 剛，小笠原康伸，諏訪峻一，寺崎浩子
  • Organizer: 第123回日本眼科学会総会
• [Presentation] 網脈絡膜疾患と脈絡膜循環 (2019)
  • Author(s): 岩瀬 剛
  • Organizer: 第36回日本眼循環学会
  • Invited
• [Presentation] OCT angiographyを用いた黄斑円孔閉鎖後の脈絡膜移動の評価 (2019)
  • Author(s): 後藤健介，岩瀬剛，赤堀友彦，寺﨑浩子
  • Organizer: 第36回日本眼循環学会
• [Presentation] 正常眼の眼圧上昇時における視神経乳頭の自己調節機能の検討 (2019)
  • Author(s): 冨田遼, 岩瀬剛, 山本健太郎, 羅英明, 寺崎浩子
  • Organizer: 第36回日本眼循環学会
• [Presentation] 27ゲージ針を用いた硝子体手術中の脈絡膜剥離の排液の新しい手技 (2019)
  • Author(s): 岩瀬 剛，羅 英明，寺﨑浩子
  • Organizer: 第73回日本臨床眼科学会
• [Presentation] ファブリー病患者における眼所見の検討 (2019)
  • Author(s): 恒川明季，岩瀬 剛，後藤裕美，山本浩志，坪井一哉
  • Organizer: 第73回日本臨床眼科学会
• [Presentation] OCT angiographyを用いた黄斑前膜術前後の黄斑部網膜の移動の評価 (2019)
  • Author(s): 百田綾菜，岩瀬 剛，赤堀友彦，山本健太郎，羅 英明，寺崎浩子
  • Organizer: 第73回日本臨床眼科学会
• [Presentation] 裂孔原性網膜剥離の術後残存黄斑下液が視力・黄斑形態に与える影響 (2019)
  • Author(s): 冨田 遼，岩瀬 剛，古林充里，後藤健介，羅 英明，寺崎浩子
  • Organizer: 第58回日本網膜硝子体学会
• [Presentation] 特発性黄斑円孔に対する硝子体手術前後の網脈絡膜血流の検討 (2019)
  • Author(s): 後藤健介，岩瀬 剛，寺崎浩子
  • Organizer: 第58回日本網膜硝子体学会
• [Presentation] Macular displacement after vitrectomy on eyes with idiopathic macular hole determined by optical coherence tomography angiography (2018)
  • Author(s): Iwase T, Akahori T, Yamamoto K, Ra E, Kawano K, Terasaki H.
  • Organizer: The Association for Research in Vision and Ophthalmology 2018
  • Int'l Joint Research
• [Presentation] OCT angiography を用いた黄斑円孔閉鎖後の黄斑部網膜の移動の評価 (2018)
  • Author(s): Ueno Y, Iwase T, Mikoshiba Y, Yamamoto K, Ra E, Terasaki H.
  • Organizer: 第72回 日本臨床眼科学会
• [Presentation] Changes in choroidal blood flow and morphology after panretinal photocoagulation in eyes with severe nonproliferative diabetic retinopathy (2018)
  • Author(s): Ueno Y, Iwase T, Mikoshiba Y, Yamamoto K, Ra E, Terasaki H.
  • Organizer: The Association for Research in Vision and Ophthalmology 2018
  • Int'l Joint Research
• [Presentation] Changes in retinochoroidal blood flow and morphology on the macula and around optic nerve head after vitrectomy for epi-retinal membrane (2018)
  • Author(s): Hirata N, Iwase T, Kobayashi M, Yamamoto K, Ra E, Kawano K, Terasaki H.
  • Organizer: The Association for Research in Vision and Ophthalmology 2018
  • Int'l Joint Research
• [Presentation] Relationship between abnormalities of photoreceptor microstructures and microvascular structures determined by optical coherence tomography angiography in eyes with branch retinal vein occlusion (2018)
  • Author(s): Iwase T, Terasaki H.
  • Organizer: 18th EURETINA congress
  • Int'l Joint Research
• [Presentation] Relationship between ocular microcirculation and renal function in patients with diabetes and chronic kidney disease (2018)
  • Author(s): Ueno Y, Iwase T, Mikoshiba Y, Yamamoto K, Ra E, Goto K, Terasaki H.
  • Organizer: 12th Congress of Asia Pacific Vitreo-Retina Society
  • Int'l Joint Research
• [Presentation] The correlation between intraretinal cyst and pre- or post-operative characteristics of idiopathic macular hole (2018)
  • Author(s): Goto K, Iwase T, Tomita R, Ueno Y, Terasaki H.
  • Organizer: 12th Congress of Asia Pacific Vitreo-Retina Society
  • Int'l Joint Research
• [Presentation] 特発性黄斑円孔における網膜内cystと黄斑円孔の形態との関連 (2018)
  • Author(s): 後藤健介，岩瀬剛，冨田遼，上野圭貴，寺崎浩子
  • Organizer: 第57回日本網膜硝子体学会総会
• [Presentation] 網膜静脈分枝閉塞症患者の僚眼における網膜動静脈交差部の網膜静脈狭窄率の検討 (2018)
  • Author(s): 冨田 遼，岩瀬 剛，上野 圭貴，後藤 健介，羅 英明，寺崎浩子
  • Organizer: 第57回日本網膜硝子体学会総会
• [Presentation] 前増殖糖尿病網膜症への従来とパターンスキャンレーザーによる汎網膜光凝固と眼血流 (2017)
  • Author(s): 岩瀬 剛，御子柴雄司，上野 圭貴，山本健太郎、羅 英明、寺崎 浩子
  • Organizer: 第56回日本網膜硝子体学会総会
• [Presentation] 裂孔原性網膜剥離に対するsegmental buckling術後早期の眼血流変化 (2017)
  • Author(s): 岩瀬 剛，古林充里，山本健太郎，柳田紘生，羅 英明，寺崎浩子
  • Organizer: 第121回日本眼科学会総会
• [Presentation] Change in choroidal blood flow and morphology after segmental scleral buckling for rhegmatogenous retinal detachment (2017)
  • Author(s): Takeshi Iwase, Misato Kobayashi, Kentaro Yamamoto, Hiroko Terasaki
  • Organizer: The Association for Research in Vision and Ophthalmology
  • Int'l Joint Research
• [Presentation] 黄斑円孔、黄斑上膜、裂孔原性網膜剥離に対する水晶体温存硝子体術後の屈折値の推移 (2017)
  • Author(s): 岩瀬 剛、古林充里、山本健太郎、柳田紘生、羅英明、寺崎浩子
  • Organizer: 第56回日本白内障学会総会
• [Presentation] Vitrectomy in complicated cases (2017)
  • Author(s): Takeshi Iwase
  • Organizer: 10th Japan-Korea-China joint meeting
  • Invited
• [Book] 眼科疾患 最新の治療2019-2021 裂孔原性網膜剥離 (2019)
  • Author(s): 岩瀬 剛
  • Publisher: 医学書院
• [Book] “実戦 メディカル眼科治療アップデート”メディカル眼科治療 網膜硝子体疾患 (2019)
  • Author(s): 岩瀬 剛
  • Publisher: 医学書院