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Development of a new root canal cleaning method that applies nanobubbles activated by laser irradiation under ultrasonic vibration

Research Project

Project/Area Number 17K11700
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeMulti-year Fund
Section一般
Research Field Conservative dentistry
Research InstitutionTokyo Medical and Dental University

Principal Investigator

Watanabe Satoshi  東京医科歯科大学, 大学院医歯学総合研究科, 助教 (50549938)

Project Period (FY) 2017-04-01 – 2021-03-31
Project Status Completed (Fiscal Year 2020)
Budget Amount *help
¥4,680,000 (Direct Cost: ¥3,600,000、Indirect Cost: ¥1,080,000)
Fiscal Year 2019: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2018: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2017: ¥2,470,000 (Direct Cost: ¥1,900,000、Indirect Cost: ¥570,000)
KeywordsLAI / ナノバブル / 超音波
Outline of Final Research Achievements

In recent years, a technique called LAI (Laser-Activated Irrigation), which applies a laser irradiation device, has been devised as a new root canal cleaning method in endodontic treatment, and is expected to improve the cleaning ability. We focused on this method and analyzed the behavior of vaporized bubbles, the pressure outside the apical foramen, and the cleaning effect in comparison with the ultrasonic cleaning method (PUI). It was confirmed that the cleaning behavior was significantly improved. These achievements were summarized in 10 peer-reviewed papers, including 5 papers with impact factor and 1 award-winning paper, which were highly evaluated both in Japan and overseas.

Academic Significance and Societal Importance of the Research Achievements

難治性根尖性歯周炎の原因菌の殺菌にはNaOCl溶液を用いたシリンジを用いた従来の根管洗浄法では根尖まで洗浄液が浸透せず、複雑な根管形態に潜む感染源まで到達させることは困難であるため、効果的な根管洗浄法の開発は世界的に喫緊の課題と認識されている。本研究課題では新しい根管洗浄法の発展としてレーザーをどのように応用すれば、より洗浄効果が高まるかを検討し、各種洗浄条件を見出した。

Report

(5 results)
  • 2020 Annual Research Report   Final Research Report ( PDF )
  • 2019 Research-status Report
  • 2018 Research-status Report
  • 2017 Research-status Report
  • Research Products

    (38 results)

All 2021 2020 2019 2018 2017

All Journal Article (11 results) (of which Int'l Joint Research: 3 results,  Peer Reviewed: 10 results) Presentation (20 results) (of which Int'l Joint Research: 1 results) Book (7 results)

  • [Journal Article] Effect of tip insertion depth and irradiation parameters on the efficacy of cleaning calcium hydroxide from simulated lateral canals using Er:YAG laser- or ultrasonic-activated irrigation2021

    • Author(s)
      Hoshihara Yasuhiro、Watanabe Satoshi、Kouno Akira、Yao Kanako、Okiji Takashi
    • Journal Title

      Journal of Dental Sciences

      Volume: 16 Issue: 2 Pages: 654-660

    • DOI

      10.1016/j.jds.2020.10.004

    • Related Report
      2020 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Effects of heating on the physical properties of premixed calcium silicate-based root canal sealers2021

    • Author(s)
      Yamauchi Shinya、Watanabe Satoshi、Okiji Takashi
    • Journal Title

      Journal of Oral Science

      Volume: 63 Issue: 1 Pages: 65-69

    • DOI

      10.2334/josnusd.20-0325

    • NAID

      130007959200

    • ISSN
      1343-4934, 1880-4926
    • Related Report
      2020 Annual Research Report
  • [Journal Article] Intracanal Vaporized Bubble Kinetics and Apical Pressure During Root Canal Irrigation Activated by Er:YAG laser:2020

    • Author(s)
      KOUNO Akira、WATANABE Satoshi、YAO Kanako、SATAKE Kazuhisa、OKIJI Takashi
    • Journal Title

      Journal of Japanese Society for Laser Dentistry

      Volume: 30 Issue: 2 Pages: 57-62

    • DOI

      10.5984/jjpnsoclaserdent.30.57

    • NAID

      130007897357

    • ISSN
      0917-7450, 2185-6702
    • Related Report
      2020 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Effect of Pulse Energy, Pulse Frequency, and Tip Diameter on Intracanal Vaporized Bubble Kinetics and Apical Pressure During Laser-Activated Irrigation Using Er:YAG Laser2020

    • Author(s)
      Kouno Akira、Watanabe Satoshi、Hongo Tomoyuki、Yao Kanako、Satake Kazuhisa、Okiji Takashi
    • Journal Title

      Photobiomodulation, Photomedicine, and Laser Surgery

      Volume: 38 Issue: 7 Pages: 431-437

    • DOI

      10.1089/photob.2019.4739

    • Related Report
      2020 Annual Research Report 2019 Research-status Report
    • Peer Reviewed
  • [Journal Article] Fluid Movement in the Apical Area Beyond the Ledge During Er:YAG Laser-Activated Irrigation: A Particle Image Velocimetry Analysis2020

    • Author(s)
      Aung NyeinPyaeSone、Watanabe Satoshi、Kouno Akira、Hongo Tomoyuki、Yao Kanako、Satake Kazuhisa、Okiji Takashi
    • Journal Title

      Photobiomodulation, Photomedicine, and Laser Surgery

      Volume: 38 Issue: 7 Pages: 438-443

    • DOI

      10.1089/photob.2019.4758

    • Related Report
      2020 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Evaluation of apical pressure during root canal irrigant activation using a diode laser with an optothermal converter-coated tip2019

    • Author(s)
      Hongo T, Watanabe S, Kouno A, Yamauchi S, Hoshinara Y, Yao K, Satake K and Okiji T.
    • Journal Title

      日本歯科保存学会雑誌

      Volume: 6 Pages: 304-310

    • NAID

      130007783228

    • Related Report
      2019 Research-status Report
    • Peer Reviewed
  • [Journal Article] Hongo T, Watanabe S, Yao K, Satake K, Okiji T. Evaluation of cleaning efficacy-related properties of root canal irrigant activation using a computer-controlled hot tippowered with a diode laser2019

    • Author(s)
      Hongo T, Watanabe S, Yao K, Satake K, Okiji T. Evaluation of cleaning efficacy-related properties of root canal irrigant activation using a computer-controlled hot tippowered with a diode laser
    • Journal Title

      Asian Pacific Journal of Dentistry

      Volume: 19 Pages: 9-15

    • Related Report
      2019 Research-status Report
    • Peer Reviewed
  • [Journal Article] Evaluation of cleaning efficacy-related properties of root canal irrigant activation using a computer-controllde hot tip powered with diode laser2019

    • Author(s)
      Hongo T, Watanabe S, Yao K, Satake K, Okiji T
    • Journal Title

      Asian Pac J Dent

      Volume: 19 Pages: 9-15

    • Related Report
      2018 Research-status Report
    • Peer Reviewed / Int'l Joint Research
  • [Journal Article] A Review of LLLT in Dentistry:2018

    • Author(s)
      渡辺 聡, 高野 晃, 本郷 智之, 八尾 香奈子, 興地 隆史
    • Journal Title

      Journal of Japanese Society for Laser Dentistry

      Volume: 29 Issue: 1 Pages: 10-25

    • DOI

      10.5984/jjpnsoclaserdent.29.10

    • NAID

      130007590581

    • ISSN
      0917-7450, 2185-6702
    • Related Report
      2018 Research-status Report
    • Peer Reviewed / Int'l Joint Research
  • [Journal Article] Apical Extrusion of Irrigating Solution during Root Canal Irrigation Activated by Er:YAG Laser : Effect of Tip Insertion Depth2017

    • Author(s)
      渡辺聡,高野晃,本郷智之,佐竹和久,井手彩集,八尾香奈子,興地隆史.
    • Journal Title

      Journal of Japanese Society for Laser Dentistry

      Volume: 28 Issue: 2+3 Pages: 31-35

    • DOI

      10.5984/jjpnsoclaserdent.28.31

    • NAID

      130006351379

    • ISSN
      0917-7450, 2185-6702
    • Related Report
      2017 Research-status Report
    • Peer Reviewed
  • [Journal Article] Effect of laser energy and tip insertion depth on the pressure generated outside the apical foramen during Er:YAG laser-activated root canal irrigation2017

    • Author(s)
      Yao K, Satake K, Watanabe S, Ebihara A, Kobayashi C, Okiji T.
    • Journal Title

      Photomedicine and Laser Surgery

      Volume: 35 Issue: 12 Pages: 682-687

    • DOI

      10.1089/pho.2017.4268

    • Related Report
      2017 Research-status Report
    • Peer Reviewed / Int'l Joint Research
  • [Presentation] 加熱によるペーストタイプシーラーの理工学的特性の影響.2020

    • Author(s)
      高野晃,渡辺聡,山内慎也,興地隆史.
    • Organizer
      日本歯科保存学会2020年度秋季学術大会(第153回)
    • Related Report
      2020 Annual Research Report
  • [Presentation] Er:YAGレーザーを用いた根管洗浄における破折器具根尖側での根管内蒸気泡の挙動. 第41回日本歯内療法学会学術大会2020

    • Author(s)
      劉嘉懿,渡辺聡,高野晃,八尾香奈子,佐竹和久,興地隆史.
    • Organizer
      第41回日本歯内療法学会学術大会
    • Related Report
      2020 Annual Research Report
  • [Presentation] レッジを伴う根管における各種根管洗浄法の根尖部清掃効果.2020

    • Author(s)
      Nyein Pyae Sone Aung, 渡辺聡, 高野晃,八尾香奈子,佐竹和久, 興地隆史.
    • Organizer
      第41回日本歯内療法学会学術大会
    • Related Report
      2020 Annual Research Report
  • [Presentation] Cleaning potential beyond the ledge using Er:YAG Laser-activated irrigation A particle image velocimetry analysis2019

    • Author(s)
      Aung S, Watanabe S, Kouno A, Hongo T, Yao K, Satake K, Okiji T
    • Organizer
      10th Mandalay Dental Conference
    • Related Report
      2019 Research-status Report
    • Int'l Joint Research
  • [Presentation] コーンビームCTを用いた上顎小臼歯の新分類に基づく根管形態評価2019

    • Author(s)
      薮本園子,渡辺聡,高野晃,本郷智之,八尾香奈子,佐竹和久,興地隆史
    • Organizer
      第40回日本歯内療法学会
    • Related Report
      2019 Research-status Report
  • [Presentation] 唇顎口蓋裂患者の侵襲性歯頸部吸収 レビューと矯正歯科的対応を含む症例2019

    • Author(s)
      毛利環,渡辺敦,八巻正樹,渡辺聡,興地隆史
    • Organizer
      第78回東京歯科矯正学会
    • Related Report
      2019 Research-status Report
  • [Presentation] 加熱によるケイ酸カルシウム系シーラーの理工学的性質への影響2019

    • Author(s)
      山内慎也,渡辺聡,興地隆史
    • Organizer
      第84回口腔病学会
    • Related Report
      2019 Research-status Report
  • [Presentation] Er:YAG laser activated root canal irrigation: Efficacy in cleaning lateral canals2019

    • Author(s)
      星原康宏,渡辺聡,高野晃,本郷智之,八尾香奈子,佐竹和久,興地隆史
    • Organizer
      第84回口腔病学会
    • Related Report
      2019 Research-status Report
  • [Presentation] 唇顎口蓋裂症例に発症した侵襲性歯頚部吸収(ECR) -歯内/修復治療と矯正歯科的対応-2019

    • Author(s)
      毛利環,渡辺敦,八巻正樹,山縣憲司,相原有希子,渡辺聡,興地隆史
    • Organizer
      栃木県歯科医師会
    • Related Report
      2019 Research-status Report
  • [Presentation] コーンビームCTを用いた下顎小臼歯の根管形態評価2019

    • Author(s)
      二階堂七実,渡辺聡,高野晃,本郷智之,八尾香奈子,佐竹和久,興地隆史
    • Organizer
      日本歯科保存学会2019年度秋季学術大会(第151回)
    • Related Report
      2019 Research-status Report
  • [Presentation] Er:YAG レーザーを用いた根管洗浄時に生じる蒸気泡の挙動-チップ直径および照射エネルギーによる影響-.2018

    • Author(s)
      12)高野晃,渡辺聡,本郷智之,八尾香奈子,井手彩集,佐竹和久,興地隆史.
    • Organizer
      日本歯科保存学会2018 年度春季学術大会(第148 回)
    • Related Report
      2018 Research-status Report
  • [Presentation] Er:YAG レーザーを用いた根管洗浄時に生じる根尖孔外の圧力および根管内蒸気泡の挙動-チップ直径およびチップ形態による影響-.2018

    • Author(s)
      37)高野晃,渡辺聡,本郷智之,八尾香奈子,佐竹和久,興地隆史.
    • Organizer
      第30 回日本レーザー歯学会
    • Related Report
      2018 Research-status Report
  • [Presentation] Er:YAG レーザーを用いた根管洗浄時に生じる根尖孔外の圧力および根管内蒸気泡の挙動-照射エネルギーによる影響-.2018

    • Author(s)
      42)高野晃,渡辺聡,本郷智之,八尾香奈子,佐竹和久,興地隆史.
    • Organizer
      日本歯科保存学会2018 年度秋季学術大会(第149 回)
    • Related Report
      2018 Research-status Report
  • [Presentation] Cleaning the apical area beyond the ledge using Er:YAG laser-activated irrigation: A particle image velocimetry analysis.2018

    • Author(s)
      45)AUNG Nyein Pyae Sone, 渡辺聡,高野晃,本郷智之,八尾香奈子,佐竹和久,興地隆史.
    • Organizer
      日本歯科保存学会2018年度秋季学術大会(第149回)
    • Related Report
      2018 Research-status Report
  • [Presentation] TMDU 歯髄生物学分野」興地教室のフィロソフィー 変わらないものと変えていくもの—2017

    • Author(s)
      興地隆史,渡辺 聡,砂川光宏,池田英治,海老原新,川島伸之,和達礼子,金子友厚,河村隼,小松恵.
    • Organizer
      平成28年度東京医科歯科大学同窓会C.D.E
    • Related Report
      2017 Research-status Report
  • [Presentation] Er:YAGレーザーを用いた根管洗浄時に生じる根尖孔外の圧力および蒸気泡の挙動-パルス数およびチップ形態による影響-2017

    • Author(s)
      高野晃,本郷智之,八尾香奈子,佐竹和久,渡辺聡,興地隆史.
    • Organizer
      日本歯科保存学会2017年度春季学術大会(第146 回)
    • Related Report
      2017 Research-status Report
  • [Presentation] Er:YAG レーザーを用いた根管内MTA充填材の除去可能性の検討.2017

    • Author(s)
      山内慎也,星原康宏,本郷智之,八尾香奈子,渡辺聡,興地隆史.
    • Organizer
      日本歯科保存学会2017年度春季学術大会(第146回)
    • Related Report
      2017 Research-status Report
  • [Presentation] 歯科領域におけるエビデンス.2017

    • Author(s)
      渡辺聡.
    • Organizer
      第29回日本レーザー治療学会
    • Related Report
      2017 Research-status Report
  • [Presentation] Er:YAGレーザーを用いた根管洗浄時に生じる蒸気泡の挙動-チップ形態による影響-2017

    • Author(s)
      高野晃,渡辺聡,本郷智之,八尾香奈子,佐竹和久,興地隆史.
    • Organizer
      第38回日本歯内療法学会学術大会
    • Related Report
      2017 Research-status Report
  • [Presentation] r:YAGレーザーを利用した根管洗浄:離れた位置における清掃効果.2017

    • Author(s)
      星原康宏,渡辺聡,高野晃,本郷智之,八尾香奈子,井手彩集,佐竹和久,興地隆史
    • Organizer
      日本歯科保存学会2017年度秋季学術大会(第147回)
    • Related Report
      2017 Research-status Report
  • [Book] エンドエキスパートが伝授する歯内療法の極意.2021

    • Author(s)
      渡辺 聡、興地隆史
    • Total Pages
      151
    • Publisher
      デンタルダイヤモンド社
    • ISBN
      9784885104886
    • Related Report
      2020 Annual Research Report
  • [Book] 治癒に導くエンドの秘訣2020

    • Author(s)
      渡辺 聡、興地隆史
    • Total Pages
      208
    • Publisher
      ヒョーロン・パブリッシャーズ
    • ISBN
      9784864320573
    • Related Report
      2020 Annual Research Report
  • [Book] 外部吸収(ECR)の外科的修復 マストオブ・エンドドンティックサージャリー2019

    • Author(s)
      渡辺聡,興地隆史
    • Total Pages
      184
    • Publisher
      デンタルダイヤモンド社
    • ISBN
      9784885104404
    • Related Report
      2019 Research-status Report
  • [Book] MUST OF INITIAL TREATMENT2018

    • Author(s)
      渡辺 聡、興地 隆史
    • Total Pages
      152
    • Publisher
      デンタルダイヤモンド社
    • ISBN
      9784885104145
    • Related Report
      2018 Research-status Report
  • [Book] 今こそ学ぼうCBCT 読像診断のマスターガイド.2018

    • Author(s)
      渡辺 聡、興地 隆史
    • Total Pages
      172
    • Publisher
      デンタルダイヤモンド社
    • ISBN
      9784885104008
    • Related Report
      2018 Research-status Report
  • [Book] 器材・材料からみる歯内療法のすぐれモノ2018

    • Author(s)
      渡辺 聡、興地 隆史
    • Total Pages
      196
    • Publisher
      デンタルダイヤモンド社
    • Related Report
      2018 Research-status Report
  • [Book] 大臼歯根管の解剖学的形態の特徴2017

    • Author(s)
      渡辺聡
    • Total Pages
      173
    • Publisher
      クインテッセンス出版
    • ISBN
      4781205364
    • Related Report
      2017 Research-status Report

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Published: 2017-04-28   Modified: 2022-01-27  

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