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Analysis of Biological Response of Elderly to Post-Scaling Bacteremia and Establishment of Prophylaxis by Phototherapy

Research Project

Project/Area Number 17K11984
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeMulti-year Fund
Section一般
Research Field Periodontology
Research InstitutionKanagawa Dental College (2018-2022)
Niigata University (2017)

Principal Investigator

Morozumi Toshiya  神奈川歯科大学, 歯学部, 准教授 (20444151)

Co-Investigator(Kenkyū-buntansha) 高橋 直紀  新潟大学, 医歯学系, 准教授 (80722842)
小松 康高  新潟大学, 医歯学総合病院, 助教 (40422597)
保苅 崇大  新潟大学, 医歯学総合病院, 医員 (30827621)
宮沢 春菜  新潟大学, 医歯学総合病院, 特任助教 (50733721)
Project Period (FY) 2017-04-01 – 2023-03-31
Project Status Completed (Fiscal Year 2022)
Budget Amount *help
¥4,680,000 (Direct Cost: ¥3,600,000、Indirect Cost: ¥1,080,000)
Fiscal Year 2019: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2018: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
Fiscal Year 2017: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Keywords生体応答 / ストレス / 生体侵襲 / スケーリング / エルビウムヤグレーザー / 生理指標 / ストレスマーカー / 炎症性サイトカイン / 光治療 / 高齢者 / 菌血症
Outline of Final Research Achievements

Nonsurgical periodontal treatment, including scaling and root planing (SRP), acts as a strong inflammatory stimulus and may affect biological responses and autonomic nervous system activity. In this study, we investigated the effects of subgingival scaling with an erbium YAG (Er: YAG) laser on physiological parameters and blood stress markers, in contrast to SRP with a conventional hand scaler. The results suggest that the use of the Er: YAG laser has a smaller stress load on patients.

Academic Significance and Societal Importance of the Research Achievements

観血的歯周治療の後には,菌血症によりエンドトキシンや炎症性サイトカインが全身に広がり,軽度の急性期反応を示す。また,侵襲下の生体では神経・内分泌系,免疫系,代謝系,循環器系を中心に種々の変動が見られる。これらはお互い独立したものではなく,神経・内分泌系を介して生体反応を抑制するフィードバック機構が作動し,生体の恒常性を維持している。本研究では各系統のストレスマーカーを網羅し,侵襲の種類や程度によるストレス応答の変化を解析した。本研究の結果は,歯周治療の直後に全身に起きている生体変化を多角的に解析した初めての研究であり,その学術的および社会的意義は極めて高い。

Report

(7 results)
  • 2022 Annual Research Report   Final Research Report ( PDF )
  • 2021 Research-status Report
  • 2020 Research-status Report
  • 2019 Research-status Report
  • 2018 Research-status Report
  • 2017 Research-status Report
  • Research Products

    (61 results)

All 2023 2022 2021 2020 2019 2018 2017

All Journal Article (25 results) (of which Int'l Joint Research: 4 results,  Peer Reviewed: 25 results,  Open Access: 20 results) Presentation (30 results) (of which Int'l Joint Research: 7 results,  Invited: 1 results) Book (6 results)

  • [Journal Article] Educational Effectiveness of Instruction Using Video Teaching Materials to Impart Initial Periodontal Therapy Techniques2023

    • Author(s)
      杉原 俊太郎、両角 俊哉、渕田 慎也、清水 統太、井上 允、琢磨 遼、門田 大地、櫻井 孝、小牧 基浩
    • Journal Title

      The Japanese Journal of Conservative Dentistry

      Volume: 66 Issue: 1 Pages: 26-34

    • DOI

      10.11471/shikahozon.66.26

    • ISSN
      0387-2343, 2188-0808
    • Year and Date
      2023-02-28
    • Related Report
      2022 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Association between Non-Alcoholic Steatohepatitis-Related Hepatocellular Carcinoma and Periodontopathic Bacteria: A Cross-Sectional Pilot Study2023

    • Author(s)
      Takuma Ryo、Morozumi Toshiya、Yamamoto Yuko、Kobayashi Takashi、Matsui Takaaki、Yoneda Masato、Kessoku Takaomi、Nogami Asako、Tamura Muneaki、Kamata Yohei、Sugihara Shuntaro、Nomura Yoshiaki、To Masahiro、Minabe Masato、Mitsudo Kenji、Nakajima Atsushi、Komaki Motohiro
    • Journal Title

      Applied Sciences

      Volume: 13 Issue: 6 Pages: 3893-3893

    • DOI

      10.3390/app13063893

    • Related Report
      2022 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Effect of Locally Delivered Minocycline on the Profile of Subgingival Bacterial Genera in Patients with Periodontitis: A Prospective Pilot Study2022

    • Author(s)
      Morozumi Toshiya、Nakayama Yohei、Shirakawa Satoshi、Imamura Kentaro、Nohno Kaname、Nagano Takatoshi、Miyazawa Haruna、Hokari Takahiro、Takuma Ryo、Sugihara Shuntaro、Gomi Kazuhiro、Saito Atsushi、Ogata Yorimasa、Komaki Motohiro
    • Journal Title

      Biomolecules

      Volume: 12 Issue: 5 Pages: 719-719

    • DOI

      10.3390/biom12050719

    • Related Report
      2022 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] A cross-sectional study assessing the relationship between non-alcoholic fatty liver disease and periodontal disease2022

    • Author(s)
      Sato Satsuki、Kamata Yohei、Kessoku Takaomi、Shimizu Tomoko、Kobayashi Takashi、Kurihashi Takeo、Takashiba Shogo、Hatanaka Kazu、Hamada Nobushiro、Kodama Toshiro、Higurashi Takuma、Taguri Masataka、Yoneda Masato、Usuda Haruki、Wada Koichiro、Nakajima Atsushi、Morozumi Toshiya、Minabe Masato
    • Journal Title

      Scientific Reports

      Volume: 12 Issue: 1 Pages: 13621-13621

    • DOI

      10.1038/s41598-022-17917-2

    • Related Report
      2022 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Periodontal Treatment and Usual Care for Nonalcoholic Fatty Liver Disease: A Multicenter, Randomized Controlled Trial2022

    • Author(s)
      Kamata Yohei、Kessoku Takaomi、Shimizu Tomoko、Sato Satsuki、Kobayashi Takashi、Kurihashi Takeo、Morozumi Toshiya、Iwasaki Tomoyuki、Takashiba Shogo、Hatanaka Kazu、Hamada Nobushiro、Kodama Toshiro、Higurashi Takuma、Taguri Masataka、Yoneda Masato、Usuda Haruki、Wada Koichiro、Nakajima Atsushi、Minabe Masato
    • Journal Title

      Clinical and Translational Gastroenterology

      Volume: 13 Issue: 11 Pages: e00520-e00520

    • DOI

      10.14309/ctg.0000000000000520

    • Related Report
      2022 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Effect of High Fat and Fructo-Oligosaccharide Consumption on Immunoglobulin A in Saliva and Salivary Glands in Rats2021

    • Author(s)
      Yamamoto Yuko、Morozumi Toshiya、Takahashi Toru、Saruta Juri、Sakaguchi Wakako、To Masahiro、Kubota Nobuhisa、Shimizu Tomoko、Kamata Yohei、Kawata Akira、Tsukinoki Keiichi
    • Journal Title

      Nutrients

      Volume: 13 Issue: 4 Pages: 1252-1252

    • DOI

      10.3390/nu13041252

    • Related Report
      2021 Research-status Report
    • Peer Reviewed / Open Access
  • [Journal Article] Estimation of the Periodontal Inflamed Surface Area by Simple Oral Examination2021

    • Author(s)
      Nomura Y, Morozumi T*, Numabe Y, Ogata Y, Nakayama Y, Sugaya T, Nakamura T, Sato S, Takashiba S, Sekino S, Yoshinari N, Hanada N, Sugano N, Fukuda M, Minabe M, Umeda M, Tabeta K, Takahashi K, Noguchi K, Kobayashi H, Takai H, Nishimura F, Suzuki F, Kakuta E, Yoshimura A, Saito A, Nakagawa T
    • Journal Title

      Journal of Clinical Medicine

      Volume: 10 Issue: 4 Pages: 723-723

    • DOI

      10.3390/jcm10040723

    • Related Report
      2020 Research-status Report
    • Peer Reviewed / Open Access
  • [Journal Article] Prospective Longitudinal Changes in the Periodontal Inflamed Surface Area Following Active Periodontal Treatment for Chronic Periodontitis2021

    • Author(s)
      Nomura Y, Morozumi T*, Saito A, Yoshimura A, Kakuta E, Suzuki F, Nishimura F, Takai H, Kobayashi H, Noguchi K, Takahashi K, Tabeta K, Umeda M, Minabe M, Fukuda M, Sugano N, Hanada N, Yoshinari N, Sekino S, Takashiba S, Sato S, Nakamura T, Sugaya T, Nakayama Y, Ogata Y, Numabe Y, Nakagawa T
    • Journal Title

      Journal of Clinical Medicine

      Volume: 10 Issue: 6 Pages: 1165-1165

    • DOI

      10.3390/jcm10061165

    • Related Report
      2020 Research-status Report
    • Peer Reviewed / Open Access
  • [Journal Article] Faster Short-Chain Fatty Acid Absorption from the Cecum Following Polydextrose Ingestion Increases the Salivary Immunoglobulin A Flow Rate in Rats2020

    • Author(s)
      Yamamoto Yuko、Morozumi Toshiya、Takahashi Toru、Saruta Juri、To Masahiro、Sakaguchi Wakako、Shimizu Tomoko、Kubota Nobuhisa、Tsukinoki Keiichi
    • Journal Title

      Nutrients

      Volume: 12 Issue: 6 Pages: 1745-1745

    • DOI

      10.3390/nu12061745

    • Related Report
      2020 Research-status Report
    • Peer Reviewed / Open Access
  • [Journal Article] Inhibitory effect of omega-3 fatty acids on alveolar bone resorption and osteoclast differentiation2020

    • Author(s)
      Ozaki Yu、Morozumi Toshiya、Watanabe Kiyoko、Toyama Toshizo、Sasaki Haruka、Sato Takenori、Yamamoto Yuko、To Masahiro、Inaba Keitaro、Tsukinoki Keiichi、Hamada Nobushiro、Minabe Masato
    • Journal Title

      Journal of Oral Science

      Volume: 62 Issue: 3 Pages: 298-302

    • DOI

      10.2334/josnusd.19-0267

    • NAID

      130007863825

    • ISSN
      1343-4934, 1880-4926
    • Related Report
      2020 Research-status Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Effect of Periodontal Disease on Diabetic Retinopathy in Type 2 Diabetic Patients: A Cross-Sectional Pilot Study2020

    • Author(s)
      Yamamoto Yuko、Morozumi Toshiya、Hirata Takahisa、Takahashi Toru、Fuchida Shinya、Toyoda Masami、Nakajima Shigeru、Minabe Masato
    • Journal Title

      Journal of Clinical Medicine

      Volume: 9 Issue: 10 Pages: 3234-3234

    • DOI

      10.3390/jcm9103234

    • Related Report
      2020 Research-status Report
    • Peer Reviewed / Open Access
  • [Journal Article] Optimal Examination Sites for Periodontal Disease Evaluation: Applying the Item Response Theory Graded Response Model2020

    • Author(s)
      Nomura Y, Morozumi T*, Fukuda M, Hanada N, Kakuta E, Kobayashi H, Minabe M, Nakamura T, Nakayama Y, Nishimura F, Noguchi K, Numabe Y, Ogata Y, Saito A, Sato S, Sekino S, Sugano N, Sugaya T, Suzuki F, Takahashi K, Takai H, Takashiba S, Umeda M, Yoshie H, Yoshimura A, Yoshinari N, Nakagawa T
    • Journal Title

      Journal of Clinical Medicine

      Volume: 9 Issue: 11 Pages: 3754-3754

    • DOI

      10.3390/jcm9113754

    • Related Report
      2020 Research-status Report
    • Peer Reviewed / Open Access
  • [Journal Article] Inhibitory effect of omega-3 fatty acids on alveolar bone resorption and osteoclast differentiation2020

    • Author(s)
      Ozaki Y, Morozumi T*, Watanabe K, Toyama T, Sasaki H, Sato T, Yamamoto Y, To M, Inaba K, Tsukinoki K, Hamada N, Minabe M
    • Journal Title

      Journal of Oral Science

      Volume: in press

    • NAID

      130007863825

    • Related Report
      2019 Research-status Report
    • Peer Reviewed
  • [Journal Article] Effect of Ingesting Yogurt Fermented With Lactobacillus Delbrueckii Ssp. bulgaricus OLL1073R-1 on Influenza Virus-Bound Salivary IgA in Elderly Residents of Nursing Homes: A Randomized Controlled Trial2019

    • Author(s)
      Yamamoto Y, Saruta J, Takahashi T, To M, Shimizu T, Hayashi T, Morozumi T, Kubota N, Kamata Y, Makino S, Kano H, Hemmi J, Asami Y, Nagai T, Misawa K, Kato S, Tsukinoki K.
    • Journal Title

      Acta Odontologica Scandinavica

      Volume: 77(7) Issue: 7 Pages: 517-524

    • DOI

      10.1080/00016357.2019.1609697

    • Related Report
      2019 Research-status Report
    • Peer Reviewed / Open Access
  • [Journal Article] Biological responses following one‐stage full‐mouth scaling and root planing with and without azithromycin: Multicenter randomized trial2019

    • Author(s)
      Yashima Akihiro、Morozumi Toshiya、Yoshie Hiromasa、Hokari Takahiro、Izumi Yuichi、Akizuki Tatsuya、Mizutani Koji、Takamatsu Hideyuki、Minabe Masato、Miyauchi Satomi、Yoshino Toshiaki、Tanaka Maki、Tanaka Yoshie、Gomi Kazuhiro
    • Journal Title

      Journal of Periodontal Research

      Volume: 54 Issue: 6 Pages: 709-719

    • DOI

      10.1111/jre.12680

    • Related Report
      2019 Research-status Report
    • Peer Reviewed / Open Access
  • [Journal Article] Smoking and periodontal microorganisms2019

    • Author(s)
      Hanioka T, Morita M, Yamamoto T, Inagaki K, Wang P-L, Ito H, Morozumi T, Takeshita T, Suzuki N, Shigeishi H, Sugiyama M, Ohta K, Nagao T, Hanada N, Ojima M, Ogawa H
    • Journal Title

      The Japanese Dental Science Review

      Volume: 55 Issue: 1 Pages: 88-94

    • DOI

      10.1016/j.jdsr.2019.03.002

    • NAID

      50014414225

    • Related Report
      2018 Research-status Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Effect of ingesting yogurt fermented with Lactobacillus delbrueckii ssp. bulgaricus OLL1073R-1 on influenza virus-bound salivary IgA in elderly residents of nursing homes: A randomized controlled trial2019

    • Author(s)
      Yamamoto Y, Saruta J, Takahashi T, To M, Shimizu T, Hayashi T, Morozumi T, Kubota N, Kamata Y, Makino S, Kano H, Hemmi J, Asami Y, Nagai T, Misawa K, Kato S, Tsukinoki K
    • Journal Title

      Acta Odontologica Scandinavica

      Volume: 印刷中

    • Related Report
      2018 Research-status Report
    • Peer Reviewed
  • [Journal Article] Effects of antimicrobial photodynamic therapy and local administration of minocycline on clinical, microbiological, and inflammatory markers of periodontal pockets: A pilot study2018

    • Author(s)
      Hokari T, Morozumi T, Komatsu Y, Shimizu T, Yoshino T, Tanaka M, Tanaka Y, Nohno K, Kubota T, Yoshie H
    • Journal Title

      International Journal of Dentistry

      Volume: - Pages: 1-9

    • DOI

      10.1155/2018/1748584

    • Related Report
      2018 Research-status Report 2017 Research-status Report
    • Peer Reviewed / Open Access
  • [Journal Article] Clinical and cone-beam CT evaluation of combinational periodontal regenerative therapies using enamel matrix derivative and deproteinized bovine bone mineral with or without collagen membrane2018

    • Author(s)
      Nemoto Y, Kubota T, Nohno K, Nezu A, Morozumi T, Yoshie H
    • Journal Title

      International Journal of Periodontics & Restorative Dentistry

      Volume: 印刷中 Issue: 3 Pages: 373-381

    • DOI

      10.11607/prd.3288

    • Related Report
      2018 Research-status Report 2017 Research-status Report
    • Peer Reviewed
  • [Journal Article] Increased systemic levels of inflammatory mediators following one-stage full-mouth scaling and root planing2018

    • Author(s)
      Morozumi T, Yashima A, Gomi K, Ujiie Y, Izumi Y, Akizuki T, Mizutani K, Takamatsu H, Minabe M, Miyauchi S, Yoshino T, Tanaka M, Tanaka Y, Hokari T, Yoshie H
    • Journal Title

      Journal of Periodontal Research

      Volume: 印刷中 Issue: 4 Pages: 536-544

    • DOI

      10.1111/jre.12543

    • Related Report
      2018 Research-status Report 2017 Research-status Report
    • Peer Reviewed
  • [Journal Article] A comparable study of combinational regenerative therapies comprising enamel matrix derivative plus deproteinized bovine bone mineral with or without collagen membrane in periodontitis patients with intrabony defects2018

    • Author(s)
      Kubota T, Nemoto Y, Nohno K, Nezu A, Morozumi T, Yoshie H
    • Journal Title

      Open Journal of Stomatology

      Volume: 8 Issue: 09 Pages: 277-286

    • DOI

      10.4236/ojst.2018.89026

    • Related Report
      2018 Research-status Report
    • Peer Reviewed / Open Access
  • [Journal Article] Assessing the progression of chronic periodontitis using subgingival pathogen levels: a 24-month prospective multicenter cohort study.2017

    • Author(s)
      Kakuta E, Nomura Y, Morozumi T, et al.
    • Journal Title

      BMC Oral Health.

      Volume: 17 Issue: 1 Pages: 46-46

    • DOI

      10.1186/s12903-017-0337-x

    • Related Report
      2017 Research-status Report
    • Peer Reviewed / Open Access
  • [Journal Article] Expression of neprilysin in periodontitis-affected gingival tissues.2017

    • Author(s)
      Nezu A, Kubota T, Maruyama S, Nagata M, Nohno K, Morizumi T, Yoshie H.
    • Journal Title

      Arch Oral Biol.

      Volume: 79 Pages: 35-41

    • DOI

      10.1016/j.archoralbio.2017.03.003

    • Related Report
      2017 Research-status Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Application of Er:YAG Laser in Periodontal Therapy and Its Possibility for Novel Prophylactic Method against Transient Bacteremia2017

    • Author(s)
      小松康高、両角俊哉、吉江弘正
    • Journal Title

      Nippon Laser Igakkaishi

      Volume: 38 Issue: 2 Pages: 158-166

    • DOI

      10.2530/jslsm.jslsm-38_0024

    • NAID

      130006163797

    • ISSN
      0288-6200, 1881-1639
    • Related Report
      2017 Research-status Report
    • Peer Reviewed
  • [Journal Article] Site-level progression of periodontal disease during a follow-up period2017

    • Author(s)
      Nomura Yoshiaki、Yoshimura Atsutoshi、Hara Yoshitaka、Nakamura Toshiaki、Noguchi Kazuyuki、Kakuta Erika、Hanada Nobuhiro、Takashiba Shogo、Amitani Yasuharu、Yoshie Hiromasa、他
    • Journal Title

      PLOS ONE

      Volume: 12 Issue: 12 Pages: e0188670-e0188670

    • DOI

      10.1371/journal.pone.0188670

    • Related Report
      2017 Research-status Report
    • Peer Reviewed / Open Access
  • [Presentation] 糖尿病モデルラットにおける顎下腺組織IgA濃度とplgR発現量の解析2022

    • Author(s)
      山本裕子,猿田樹理,坂口和歌子,窪田展久,東 雅啓,清水智子,両角俊哉,高橋 徹,高垣裕子,槻木恵一
    • Organizer
      第76回日本栄養・食糧学会大会
    • Related Report
      2022 Annual Research Report
  • [Presentation] 歯周基本治療手技における動画教材の有効性検討2022

    • Author(s)
      両角俊哉, 渕田慎也, 櫻井 孝
    • Organizer
      第41回日本歯科医学教育学会総会および学術大会
    • Related Report
      2022 Annual Research Report
  • [Presentation] 全身性疾患への影響を考慮した新たな歯周病重症度検査項目の策定~学会主導型多施設臨床研究~2022

    • Author(s)
      松田真司,菅谷 勉,加藤幸紀,根本英二,竹内康雄,喜田大智,沼部幸博,西田哲也, 小方賴昌,申 基喆,長野孝俊,両角俊哉,小松康高,出分菜々衣,神谷洋介,北村正博,田口洋一郎,高柴正悟,湯本浩通,山下明子,吉永泰周,吉村篤利,河口浩之
    • Organizer
      第65回秋季日本歯周病学会学術大会
    • Related Report
      2022 Annual Research Report
  • [Presentation] 非アルコール性脂肪性肝炎由来肝細胞がんにおける歯周病の関与2022

    • Author(s)
      琢磨 遼,両角俊哉,松井嵩昌,山本裕子,結束貴臣,米田正人,野上麻子,小林 貴,杉原俊太郎,鎌田要平,田村宗明,光藤健司,中島 淳,三邉正人,小牧基浩
    • Organizer
      第65回秋季日本歯周病学会学術大会
    • Related Report
      2022 Annual Research Report
  • [Presentation] ラード摂取量の違いがラット唾液中IgAレベルに与える影響の検討2022

    • Author(s)
      山本裕子,井出 桃,両角俊哉,猿田樹理,坂口和歌子,東 雅啓,清水智子,槻木恵一
    • Organizer
      日本歯科衛生学会 第17回学術大会
    • Related Report
      2022 Annual Research Report
  • [Presentation] 短鎖脂肪酸経口摂取がラット唾液中IgA分泌速度に与える影響の検討2022

    • Author(s)
      山本裕子,高橋 徹,猿田樹理,坂口和歌子,両角俊哉,東 雅啓,槻木恵一
    • Organizer
      第1回日本唾液ケア研究会学術集会
    • Related Report
      2022 Annual Research Report
  • [Presentation] 医科歯科連携による歯周病と糖尿病のスクリーニング検査及びその有用性の検討2021

    • Author(s)
      平田貴久, 両角俊哉, 青木一孝, 三邉正人
    • Organizer
      第64回日本糖尿病学会年次学術集会
    • Related Report
      2021 Research-status Report
  • [Presentation] 糖尿病専門クリニックに通院 中の糖尿病患者における糖尿病と歯周病の病態の関連性2021

    • Author(s)
      山本裕子, 両角俊哉, 平田貴久,渕田慎也, 琢磨 遼, 三邉正人
    • Organizer
      第64回春季日本歯周病学会学術 大会
    • Related Report
      2021 Research-status Report
  • [Presentation] 歯周病評価における最適検査部位の選定 ―項目反応理論 Graded response modelの応用―2021

    • Author(s)
      両角俊哉, 野村義明, 福田光男, 花田信弘, 角田衣理加, 小林宏明, 三邉正人, 中村利明, 中 山洋平, 西村英紀, 野口和行, 沼部幸博, 小方頼昌, 齋藤 淳, 佐藤 聡, 関野 諭, 菅野直之, 菅谷 勉, 鈴木史彦, 多部田康一, 高橋慶壮, 高井英樹, 高柴正悟, 梅田 誠, 吉江弘正, 吉村 篤利, 吉成伸夫, 中川種昭
    • Organizer
      第64回春季日本歯周病学会学術大会
    • Related Report
      2021 Research-status Report
  • [Presentation] トモシンセシス法を用いたパノラマX線画像における歯周組織所見の主観的および物理学的画質評価2021

    • Author(s)
      杉原俊太郎, 両角俊哉, 三邉正人
    • Organizer
      日本歯科保存学会2021年度春季学術大会(第154回)
    • Related Report
      2021 Research-status Report
  • [Presentation] 歯周病のポケット選定における代表歯・部位の選定2021

    • Author(s)
      両角俊哉, 高柴正悟, 三邉正人, 野村義明, 福田光男, 花田信弘, 角田衣理加, 小林宏明,中 村利明, 中山洋平, 西村英紀, 野口和行, 沼部幸博, 小方頼昌, 齋藤 淳, 佐藤 聡, 関野 諭, 菅野直之, 菅谷 勉, 鈴木史彦, 多部田康一, 高橋慶壮, 高井英樹,梅田 誠, 吉江弘正, 吉村 篤利, 吉成伸夫, 中川種昭
    • Organizer
      第14回 日本口腔検査学会総会・学術大会
    • Related Report
      2021 Research-status Report
  • [Presentation] トモシンセシス法を用いたパノラマX線画像における硬組織所見の主観的および物理学的画質評価2021

    • Author(s)
      杉原俊太郎, 両角俊哉, 香西雄介, 印南 永
    • Organizer
      第56回神奈川歯科大学学会総会
    • Related Report
      2021 Research-status Report
  • [Presentation] 医科歯科連携による歯周病、糖尿病のスクリーニング検査とその有用性の検討2021

    • Author(s)
      平田貴久, 両角俊哉, 杉原俊太郎, 門田大地, 青木一孝
    • Organizer
      第56回神奈川歯科大学学会総会
    • Related Report
      2021 Research-status Report
  • [Presentation] 歯周病ポケット検査における代表歯・部位の選定2021

    • Author(s)
      両角俊哉, 野村義明, 中川種昭, 沼部幸博, 菅谷 勉, 佐藤 聡, 野口和行, 吉成伸夫, 吉村 篤利, 西村英紀, 齋藤 淳, 福田光男, 小林宏明, 菅野直之, 多部田康一, 高橋慶壮, 梅田 誠, 高柴正悟, 三邉正人, 小方賴昌
    • Organizer
      第56回神奈川歯科大学学会総会
    • Related Report
      2021 Research-status Report
  • [Presentation] 歯周基本治療講義における動画教材の有効性検討2021

    • Author(s)
      両角俊哉, 杉原俊太郎, 渕田慎也, 清水統太, 井上 允, 小牧基浩
    • Organizer
      神奈川歯科大学学会第167回例会
    • Related Report
      2021 Research-status Report
  • [Presentation] 糖尿病専門クリニックに通 院中の糖尿病患者における糖尿病と歯周病の病態の関連性 第3報2019

    • Author(s)
      山本裕子, 両角俊哉, 青山典生, 平田貴久, 渕田愼也, 三辺正人
    • Organizer
      第62回春季日本歯周 病学会学術大会
    • Related Report
      2019 Research-status Report
  • [Presentation] Effect of Ingesting Yogurt Fermented with Lactobacillus delbrueckii ssp. bulgaricus OLL1073R-1 on Influenza Virus-Bound Salivary IgA in Elderly People2019

    • Author(s)
      Yamamoto Y, Saruta J, Takahashi T, To M, Shimizu T, Morozumi T, Kubota N, Makino S, Kano H, Tsukinoki K
    • Organizer
      13th International Scientific Conference on Probiotics, Prebiotics, Gut Microbiota and Health
    • Related Report
      2019 Research-status Report
    • Int'l Joint Research
  • [Presentation] Smoking status and social nicotine dependence among members in Japanese Society of Periodontology2019

    • Author(s)
      Inagaki K, Oh H, Hanioka T, Fujii T, Morozumi T, Ito H, Yamamoto T, Morita M
    • Organizer
      Tobacco Induced Diseases 15th Annual Conference
    • Related Report
      2019 Research-status Report
    • Int'l Joint Research
  • [Presentation] 広汎型重度慢性歯周炎患者において歯周組織再生療法と局所矯正治療により改善を認 めた一症例2018

    • Author(s)
      両角俊哉,保苅崇大,野村 隆,久保田健彦,小松康高,高橋直紀,奥田一博,三辺正人,吉江弘 正
    • Organizer
      第61回春季日本歯周病学会学術大会
    • Related Report
      2018 Research-status Report
  • [Presentation] 歯周病模型に対する従来法印象とデジタル印象法の再現性についての評価2018

    • Author(s)
      杉原俊太郎, 大野晃教, 井上絵理香, 清宮一秀, 丸尾勝一郎, 星 憲幸, 両角俊哉, 木本克彦, 三辺正人
    • Organizer
      第 61回秋季日本歯周病学会学術大会
    • Related Report
      2018 Research-status Report
  • [Presentation] Biological response and clinical effect following one-stage full-mouth scaling and root planing2018

    • Author(s)
      Toshiya Morozumi
    • Organizer
      104TH Annual Meeting of the American Academy of Periodontology
    • Related Report
      2018 Research-status Report
    • Int'l Joint Research / Invited
  • [Presentation] Expression of neprilysin in periodontitis-affected gingival tissues2017

    • Author(s)
      Nezu A, Kubota T, Maruyama S, Nagata M, Horimizu M, Nohno K, Hokari T, Morozumi T, Yoshie H
    • Organizer
      16th International Congress of Periodontology of the International Academy of Periodontology
    • Related Report
      2017 Research-status Report
    • Int'l Joint Research
  • [Presentation] Effectiveness of periodontal regenerative therapy using enamel matrix derivative, deproteinised bovine bone mineral with or without collagen membrane2017

    • Author(s)
      Kubota T, Nemoto Y, Nohno K, Morozumi T, Horimizu M, Yoshie H
    • Organizer
      16th International Congress of Periodontology of the International Academy of Periodontology
    • Related Report
      2017 Research-status Report
    • Int'l Joint Research
  • [Presentation] 歯肉縁下細菌と血清抗体価を用いた慢性歯周炎進行の評価:24ヵ月多施設前向きコホート研究2017

    • Author(s)
      両角俊哉、角田衣理加、野村義明、中川種昭、野口和行、原 宜興、西村英紀、梅田 誠、 野口俊英、吉成伸夫、沼部幸博、伊藤公一、和泉雄一、小方頼昌、三邉正人、齋藤 淳、佐藤 聡、高橋慶壮、川浪雅光、花田信弘、高柴正悟、吉江弘正
    • Organizer
      第60回春季日本歯周病学会学術大会
    • Related Report
      2017 Research-status Report
  • [Presentation] 広汎型重度慢性歯周炎患者において歯周基本治療と根分岐部病変治療(トンネリング)により改善を認めた一症例2017

    • Author(s)
      両角俊哉,保苅崇大,小松康高,久保田健彦,奥田一博,吉江弘正
    • Organizer
      第60回春季日本歯周病学会学術大会
    • Related Report
      2017 Research-status Report
  • [Presentation] Clinical and three-dimensiona evaluation of combinational periodontal regenerative therapy using enamel matrix derivative, deproteinized bovine bone mineral with or without collagen membrane2017

    • Author(s)
      Kubota T, Nemoto Y, Nohno K, Nezu A, Horimizu M, Morozumi T, Yoshie H
    • Organizer
      National Symposium OSTEOLOGY JAPAN
    • Related Report
      2017 Research-status Report
    • Int'l Joint Research
  • [Presentation] 歯肉縁下細菌と血清抗体価による慢性歯周炎進行の予知判定:24ヵ月多施設前向きコホート研究2017

    • Author(s)
      両角俊哉,中川種昭,野口和行,原 宜興,西村英紀,梅田 誠,野口俊英,吉成伸夫,沼部幸博, 伊藤公一,和泉雄一,小方頼昌,三邉正人,齋藤 淳,佐藤 聡,高橋慶壮,川浪雅光,花田信弘, 高柴正悟,吉江弘正
    • Organizer
      日本歯科保存学会2017年度春季学術大会
    • Related Report
      2017 Research-status Report
  • [Presentation] 慢性歯周炎に対する抗菌的光線力学療法と局所薬物配送システムの臨床および微生物学的効果2017

    • Author(s)
      保苅崇大,両角俊哉,小松康高,久保田健彦,吉江弘正
    • Organizer
      日本歯科保存学会2017年度春季学術大会
    • Related Report
      2017 Research-status Report
  • [Presentation] 慢性歯周炎に対する抗菌的光線力学療法と局所薬物配送システムの臨床および生物学的効果2017

    • Author(s)
      保苅崇大,両角俊哉,小松康高,清水太郎,吉野敏明,田中真喜,田中良枝,久保田健彦,吉江 弘正
    • Organizer
      平成29年度新潟歯学会第1回例会
    • Related Report
      2017 Research-status Report
  • [Presentation] Systemic and local biological response following one-stage full-mouth scaling and root planning2017

    • Author(s)
      Morozumi1 T, Yashima A, Gomi K, Ujiie Y, Izumi Y, Akizuki T, Mizutani K, Takamatsu H, Minabe M, Miyauchi S, Yoshino T, Tanaka M, Tanaka Y, Hokari T, Yoshie H
    • Organizer
      12th Asian Pacific Society of Periodontology
    • Related Report
      2017 Research-status Report
    • Int'l Joint Research
  • [Book] エキスパートが初めて明かす技のバイブル! インプラント周囲炎はEr:YAG Laserでこう治す!2022

    • Author(s)
      山本敦彦、両角俊哉、久保田健彦、浦野 智、猪子光晴、藤田 亨、富塚佳史、中西真大、小野晴彦
    • Total Pages
      108
    • Publisher
      クインテッセンス出版
    • ISBN
      9784781209074
    • Related Report
      2022 Annual Research Report
  • [Book] 歯周治療のガイドライン 20222022

    • Author(s)
      両角俊哉,他(特定非営利活動法人 日本歯周病学会 編)
    • Total Pages
      93
    • Publisher
      医歯薬出版
    • Related Report
      2021 Research-status Report
  • [Book] 第3版臨床 歯周病学2020

    • Author(s)
      三辺正人,両角俊哉
    • Total Pages
      416
    • Publisher
      医歯薬出版
    • ISBN
      9784263458440
    • Related Report
      2019 Research-status Report
  • [Book] 日本歯科評論別冊2019 歯科診療の幅を広げる医科との連携-保険算定要件から治療対応のポイントまで2019

    • Author(s)
      三辺正人,山本裕子,両角俊哉
    • Total Pages
      144
    • Publisher
      ヒョーロン・パブリッシャーズ
    • Related Report
      2019 Research-status Report
  • [Book] 歯科衛生学辞典2019

    • Author(s)
      両角俊哉
    • Total Pages
      480
    • Publisher
      永末書店
    • ISBN
      9784816013683
    • Related Report
      2019 Research-status Report
  • [Book] 患者さんのエイジングに備える 高齢者への歯周治療と口腔管理2018

    • Author(s)
      吉江弘正、両角俊哉(吉江弘正、吉成伸夫、米山武義 編)
    • Total Pages
      283
    • Publisher
      インターアクション
    • Related Report
      2017 Research-status Report

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Published: 2017-04-28   Modified: 2024-01-30  

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