Improvement of physical function by water exercise and its effect on salivary aging markers
| Project/Area Number |
17K12055
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Social dentistry
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| Research Institution | Meikai University |
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Principal Investigator |
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| Co-Investigator(Kenkyū-buntansha) |
鈴木 龍一郎 城西大学, 薬学部, 准教授 (20415201)
竹島 浩 明海大学, 歯学部, 教授 (90216888)
白瀧 義明 城西大学, 薬学部, 教授 (60077980)
坂上 宏 明海大学, 歯学部, 教授 (50138484)
増田 宜子 松本歯科大学, 歯学部, 教授 (10297038)
杉本 昌弘 東京医科大学, 医学部, 教授 (30458963)
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| Project Period (FY) |
2017-04-01 – 2020-03-31
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| Project Status |
Completed (Fiscal Year 2019)
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| Budget Amount *help |
¥4,550,000 (Direct Cost: ¥3,500,000、Indirect Cost: ¥1,050,000)
Fiscal Year 2019: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2018: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2017: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
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| Keywords | 老化マーカー / 唾液 / 水中運動 / 身体機能改善 / メタボローム解析 / 老化 / 歯学 / 運動 / 長寿命化 |
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| Outline of Final Research Achievements |
Although the menu and the degree of improvement in motor function (rehabilitation effect) differ depending on the individual who exercises in the water, "saliva" was used as a marker that serves as a simple index. So far, it has been clarified that the amounts of glycine and proline in saliva amino acids increase with aging (Sakagami et al.). As a result of research paying attention to these, it was found that there was a downward trend of these amino acids with water exercise. Also, substances in urine related to diseases and aging tended to decrease. Furthermore, there were clear differences in the 15 substances in saliva before and after exercises.
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| Academic Significance and Societal Importance of the Research Achievements |
老化予防や運動機能維持向上ならびに身体機能改善を目的とした「水中運動」は水の浮力と浮力による体重負荷の軽減、水の抵抗を利用した運動量の調節、努力性呼吸による心肺機能の向上などが期待でき、効率のよい運動条件を備えていると言われている。身体機能のリハビリや老化の予防に対する水中運動の必要量や効果判定を個人別に定量化でき、超高齢社会の福祉に大きく貢献できるものと考えられた。
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Report
(4 results)
Research Products
(25 results)
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[Journal Article] Protection of differentiating neuronal cells from amyloid β peptide-induced injury by alkaline extract of leaves of Sasa senanensis Rehder.2018
Author(s)
Sakagami H, Tsuji M,Tomomura M, Masuda Y, Iwama S, Nakagawa M, Suzuki H, Tanaka K, Abe T,Tamura N, Tomomura A, Yokose S, Takeshima H, Natori T,Horiuchi M, Fujisawa T, Kiuchi Y, Oguchi K, Yasui Y, Oizumi H and Oizumi T.
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Journal Title
In Vivo
Volume: 32
Issue: 2
Pages: 231-239
DOI
Related Report
Peer Reviewed / Open Access
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[Journal Article] Perioperative Management of a Patient with Middle Cranial Fossa Arachnoid Cysts2018
Author(s)
Toru TAKUSAGAWA, Shoko KAWAGUCHI, Masahiko KOBAYASHI, Takuya SONOKAWA, Victor Jose KITANO FLORES, Shumei YOSHIKAWA, Nobuaki TAMURA, Tsuneyasu TATSUTA, Akemi KAWAJIRI, Yuichiro OTSUKA, Mikiko MANO, Naoto SUDA, Hiroshi TAKESHIMA, ,Jun SHIMADA
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Journal Title
The Journal of Meikai Dental Medicine
Volume: 47
Pages: 105-111
NAID
Related Report
Peer Reviewed
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[Presentation] X線照射誘導性細胞傷害に対する抗酸化剤の保護効果の測定法の検討2019
Author(s)
坂上宏, 中谷儀一郎, 小川由香里, 白戸亮吉, 上田大輔, 延澤忠真, 中谷祥恵, 古旗賢二, 松田玲於奈, 田村暢章, 竹島浩
Organizer
第140回日本薬理学会関東部会
Related Report
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[Presentation] X線照射誘発性PC12神経細胞傷害に及ぼすNGFの保護効果2019
Author(s)
坂上宏, 中谷儀一郎, 小川由香里, 白戸亮吉, 上田大輔, 延澤忠真, 中谷祥恵, 古旗賢二, 松田玲於奈, 田村暢章, 刀祢重信, 坂東健二郎, 友村美根子, 友村明人, 竹島浩, 鬼頭 慎司
Organizer
第141回日本薬理学会関東部会
Related Report
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