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Learning Dementia Prevention Measures from Northern Thailand, Where There Are Few Dementia Cases: Based on the Relationship Between Cerebral Blood Flow and Lifestyle

Research Project

Project/Area Number 17K12534
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeMulti-year Fund
Section一般
Research Field Community health nursing
Research InstitutionToyama Prefectural University (2021-2023)
Ishikawa Prefectural Nursing University (2017-2020)

Principal Investigator

Shimizu Nobuko  富山県立大学, 看護学部, 准教授 (20722622)

Co-Investigator(Kenkyū-buntansha) 松永 昌宏  愛知医科大学, 医学部, 准教授 (00533960)
長谷川 昇  同志社女子大学, 看護学部, 特任教授 (10156317)
梅村 朋弘  愛知医科大学, 医学部, 講師 (10401960)
山田 恭子  佛教大学, 保健医療技術学部, 教授 (20191314)
望月 美也子  京都文教短期大学, 食物栄養学科, 准教授 (20367858)
加藤 真弓  愛知医療学院短期大学, 理学療法学専攻, 教授 (90512856)
Project Period (FY) 2017-04-01 – 2024-03-31
Project Status Completed (Fiscal Year 2023)
Budget Amount *help
¥4,810,000 (Direct Cost: ¥3,700,000、Indirect Cost: ¥1,110,000)
Fiscal Year 2020: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Fiscal Year 2019: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Fiscal Year 2018: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000)
Fiscal Year 2017: ¥2,730,000 (Direct Cost: ¥2,100,000、Indirect Cost: ¥630,000)
Keywordsタイ人高齢者 / 日本人高齢者 / 近赤外分光法(NIRS) / 二重課題 / WHO-QOL / 認知機能評価 / 社会的孤立感 / 老年期抑うつ尺度 / タイ高齢者 / 高齢者サロン / 認知機能低下予防 / 近赤外分光法 / 背外側前頭前野部位 / 社会的孤立 / LSNS-6 / 国際共同研究 / 認知機能 / 脳血流量測定 / ビタミンD / 生活習慣 / 栄養摂取状況 / 体組成 / 国際比較 / 認知機能測定評価 / 身体機能測定評価 / Web会議システム / オンライン測定法 / ミニメンタルステートテスト(MMSE) / モントリオール認知評価(MoCA) / 信仰心 / 前頭前野血流量 / 遠隔操作測定法 / 簡易認知機能評価法 / タイ / 近赤外線光脳機能イメージング装 / 認知機能面 / 宗教 / DASC-21 / ソーシャルキャピタル度 / 社会的役割 / 軽度認知症高齢者 / 前頭葉機能 / 近赤外線光脳機能イメージング装置 / タイ王国 / タイ版質問式簡易栄養摂取調査表 / バランステスト / 認知機能検査 / 脳血流量 / 認知症予防対策 / 地域高齢者
Outline of Final Research Achievements

The subjects were older adults attending senior salons in Thailand and Japan. The study was approved by the University Ethics Review Committee of the researcher's university.Multiple regression analysis of the results of 144 senior subjects (57 in Thailand and 87 in Japan), with cognitive function (MMSE, MoCA) as the dependent variable, showed that the combined Thai and Japanese senior had better GDS test scores (β=-.211, P=.015), higher Social-WHOQOL (β=. 209, P=.016), and better MMSE (β=-.209, P=.016), there was also an association between the LSNS-6 and MMSE values (β=.306, P=.021) among Thai seniors. Blood flow in the dorsolateral prefrontal cortex during word fluency and motor task performance (DT) was significantly associated (β=.412, P=.001) in the left dorsolateral prefrontal region in both countries.

Academic Significance and Societal Importance of the Research Achievements

本研究の結果から、タイと日本の高齢者において、うつ病と社会的QOLが認知機能に影響を及ぼすこと、また、タイの高齢者では、日本よりも社会的孤立が認知機能に悪影響を及ぼすことが示された。特に、高齢者のうつ病と社会的孤立を早期に発見し、予防的介入を行うことが認知機能低下の予防に有効である。本研究は、二重課題実施中の背外側前頭前皮質活動の低下が、両国において将来の認知機能低下を予測する可能性を示唆していた。

Report

(8 results)
  • 2023 Annual Research Report   Final Research Report ( PDF )
  • 2022 Research-status Report
  • 2021 Research-status Report
  • 2020 Research-status Report
  • 2019 Research-status Report
  • 2018 Research-status Report
  • 2017 Research-status Report
  • Research Products

    (37 results)

All 2023 2022 2021 2020 2019 Other

All Int'l Joint Research (7 results) Journal Article (12 results) (of which Int'l Joint Research: 4 results,  Peer Reviewed: 9 results,  Open Access: 8 results) Presentation (17 results) (of which Int'l Joint Research: 9 results) Remarks (1 results)

  • [Int'l Joint Research] 国立チェンマイ大学看護学部(タイ)

    • Related Report
      2023 Annual Research Report
  • [Int'l Joint Research] 国立チェンマイ大学看護学部(タイ)

    • Related Report
      2022 Research-status Report
  • [Int'l Joint Research] 国立チェンマイ大学看護学部(タイ)

    • Related Report
      2021 Research-status Report
  • [Int'l Joint Research] Chiang Mai University/Faculty of Nursing(タイ)

    • Related Report
      2020 Research-status Report
  • [Int'l Joint Research] Chiang Mai University Faculty of Nursing(タイ)

    • Related Report
      2019 Research-status Report
  • [Int'l Joint Research] 国立チェンマイ大学/看護学部(タイ)

    • Related Report
      2018 Research-status Report
  • [Int'l Joint Research] 国立チェンマイ大学/看護学部(タイ)

    • Related Report
      2017 Research-status Report
  • [Journal Article] Prediction of Serum Vitamin D Levels in Japanese Older Adults Using XGBoost Algorithm and Logistic Regression2023

    • Author(s)
      oboru Hasegawa Seiji Tsuchiya Minatsu Kobayashi Nobuko Shimizu Yoshihito Tsubouchi Takako Yamada Mayumi Kato Miyako Mochizuki Hunsa Sethabouppha Nattaya Suwankruhasn Chalinee Suvanayos
    • Journal Title

      International Journal of Nursing & Clinical Practices

      Volume: 10 Pages: 1-3

    • Related Report
      2023 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Prediction of Serum Vitamin D Levels in Japanese Older Adults Using XGBoost Algorithm and Logistic Regression2023

    • Author(s)
      Noboru Hasegawa, Seiji Tsuchiya, Minatsu Kobayashi, Nobuko Shimizu, Yoshihito Tsubouchi, Takako Yamada, Mayumi Kato, Miyako Mochizuki, Hunsa Sethabouppha, Nattaya Suwankruhasn and Chalinee Suvanayos
    • Journal Title

      International Journal of Nursing & Clinical Practices

      Volume: 10 Pages: 1-3

    • Related Report
      2022 Research-status Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Qualitative Study on Important Elements of Life for Japanese and Thai Older Adults2023

    • Author(s)
      Nobuko Shimizu,Takako Yamada,Nobuyuki Honda,Miyako Mochizuki,Mayumi Kato, Noboru Hasegawa, Hunsa Sethabouppha, Nattaya Suwankruhasn,Chalinee Suvanayos
    • Journal Title

      Journal of Ageing and Longevity

      Volume: 3(1) Issue: 1 Pages: 11-32

    • DOI

      10.3390/jal3010002

    • Related Report
      2022 Research-status Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] 音楽運動療法とパルス温熱療法の併用が高齢者の 認知機能に与える影響2023

    • Author(s)
      松永 昌宏, 清水 暢子, 梅村 朋弘, 冨成 祐介, 山田 恭子, 坪内 善仁, 本多 伸行, 長谷川 昇, 加藤 真弓, 望月 美也子, 石井 敬子, 堀 礼子, 若山 怜, 成定 明彦, 坪井 宏仁, 鈴木 孝太
    • Journal Title

      BIO Clinica

      Volume: 38(5) Pages: 69-72

    • Related Report
      2022 Research-status Report
  • [Journal Article] アクティブシニアの健康増進・フレイル対策における血清ビタミンDの役割2022

    • Author(s)
      長谷川昇 , 山田恭子 , 清水暢子 , 坪内善仁 , 望月美也子
    • Journal Title

      Geriatric Medicine

      Volume: 61(3) Pages: 207-210

    • Related Report
      2022 Research-status Report
  • [Journal Article] 音楽運動療法と局所的・遠隔的虚血コンディショニングの併用が高齢者の認知機能に与える影響2022

    • Author(s)
      松永 昌宏 , 清水 暢子 , 梅村 朋弘 , 冨成 祐介 , 石井 敬子 , 堀 礼子 , 若山 怜 , 成定 明彦 , 坪井宏仁 , 鈴木 孝太
    • Journal Title

      Precision Medicine

      Volume: 5(13) Pages: 1120-1123

    • Related Report
      2022 Research-status Report
  • [Journal Article] Association between Serum Vitamin D Levels and Muscle Weight of Adult Day-Care Center Clients in Three Different Latitude Areas of Japan2022

    • Author(s)
      Noboru Hasegawa, Nobuko Shimizu, Takako Yamada, Yoshihito Tsubouchi, Miyako Mochizuki, Mayumi Kato, Masashi Yoshitake, Ayako Yokota
    • Journal Title

      International Journal of Nursing & Clinical Practices

      Volume: 9 Pages: 1-5

    • Related Report
      2022 Research-status Report
    • Peer Reviewed / Open Access
  • [Journal Article] A Novel Method to Predict Cognitive and Physical Function, Muscle Weight and Quality of Life in Japanese Elderly Using Deep Learning2022

    • Author(s)
      Noboru Hasegawa, Seiji Tsuchiya,Yoshihito Tsubouchi,Takako Yamada, Nobuko Shimizu, Mayumi Kato,Miyako Mochizuk
    • Journal Title

      International Journal of Nursing & Clinical Practices

      Volume: 9(366) Pages: 1-4

    • Related Report
      2022 Research-status Report
    • Peer Reviewed / Open Access
  • [Journal Article] 地域における健康高齢者の重要な生活行為―SCATによる分析2022

    • Author(s)
      山田恭子 , 清水暢子 , 長谷川昇 , 望月美也子 , 坪内善仁
    • Journal Title

      保健医療技術学部論集

      Volume: 16 Pages: 53-68

    • Related Report
      2022 Research-status Report
    • Peer Reviewed
  • [Journal Article] Association between Serum Vitamin D Levels and Muscle Weight of Adult Day-Care Center Clients in Three Different Latitude Areas of Japan2022

    • Author(s)
      Noboru Hasegawa, Nobuko Shimizu, Takako Yamada, Yoshihito Tsubouchi, Miyako Mochizuki, Mayumi Kato, Masashi Yoshitake, Ayako Yokota
    • Journal Title

      International Journal of Nursing & Clinical Practices

      Volume: 9

    • Related Report
      2021 Research-status Report
    • Peer Reviewed / Open Access
  • [Journal Article] 地域における健康高齢者の重要な生活行為 : SCAT による分析2022

    • Author(s)
      山田恭子,清水暢子,長谷川昇,望月美也子,坪内善仁
    • Journal Title

      保健医療技術学部論集 / 佛教大学保健医療技術学部

      Volume: 16 Pages: 53-68

    • Related Report
      2021 Research-status Report
    • Peer Reviewed / Open Access
  • [Journal Article] Cognitive and Physical Assessment in the Elderly while Maintaining Social Distance Using A Web Conference System: A Pilot Study2021

    • Author(s)
      Noboru Hasegawa, Takako Yamada, Miyako Mochizuki, Yoshihito Tsubouchi, Nobuyuki Honda and Nobuko Shimizu
    • Journal Title

      International Journal of Nursing & Clinical Practices

      Volume: 8 Issue: 1 Pages: 1-5

    • DOI

      10.15344/2394-4978/2021/340

    • Related Report
      2021 Research-status Report 2020 Research-status Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Presentation] Exploration of Evidence for the Early Intervention of Cognitive Decline in Asia2023

    • Author(s)
      Shimizu N, Yamada T, Kobayashi M, Matsunaga M, Umemura T, Kato M, Hasegawa N, Sethabouppha,H, Suwankruhasn,N, Suvanayos,C
    • Organizer
      27th East Asia Forum of Nursing Scholars
    • Related Report
      2023 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Development of high-level evidence for early detection of cognitive decline by conducting and using near-infrared spectroscopy2022

    • Author(s)
      Shimizu N , Yamada T , Tsubouchi Y , Honda N , Matsunaga M , Umemura T , Mochizuki M , Kato M , Hasegawa N
    • Organizer
      26th East Asia Forum of Nursing Scholars (EAFONS2023)
    • Related Report
      2022 Research-status Report
    • Int'l Joint Research
  • [Presentation] Effects of Activity Restriction during a Pandemic on Flailing in the Older Adults Community After One Year2022

    • Author(s)
      Shimizu N , Koshida M , Saeki K , Ishimaru T
    • Organizer
      26th East Asia Forum of Nursing Scholars (EAFONS2023)
    • Related Report
      2022 Research-status Report
    • Int'l Joint Research
  • [Presentation] Qualitative study on important elements of life for Japanese and Thai older adults2022

    • Author(s)
      Shimizu N , Yamada T , Tsubouchi Y , Honda N , Matsunaga M , Umemura T , Mochizuki M , Kato M , Hasegawa N
    • Organizer
      25th East Asia Forum of Nursing Scholars (EAFONS2023)
    • Related Report
      2022 Research-status Report
    • Int'l Joint Research
  • [Presentation] 通いの場に参加する後期高齢者の介護度重症化予防のためのフレイル因子の検討2022

    • Author(s)
      清水暢子 , 越田美穂子 , 石丸敏子 , 佐伯和子
    • Organizer
      第11回日本公衆衛生看護学会学術集会
    • Related Report
      2022 Research-status Report
  • [Presentation] 高齢者の保健事業と介護予防の一体的実施に関するポピュレーションアプローチ事業の評価検討2022

    • Author(s)
      清水暢子 , 越田美穂子 , 石丸敏子 , 佐伯和子
    • Organizer
      日本地域看護学会第25回学術集会
    • Related Report
      2022 Research-status Report
  • [Presentation] 非対面による認知機能および身体機能評価の有効性の検討(パイロットスタディ)2022

    • Author(s)
      望月美也子,長谷川 昇,山田 恭子,坪内 善仁, 本多 伸行, 清水 暢子
    • Organizer
      第64回日本老年医学会学術集会
    • Related Report
      2022 Research-status Report
  • [Presentation] Relationship Between Cognitive Function and QOL in Community-dwelling Elderly: Focusing on Social Frailty2021

    • Author(s)
      Nobuyuki Honda,Noboru Hasegawa,Takako Yamada, Nobuko Shimizu, Miyako Mochizuki, Mayumi Kato
    • Organizer
      Malaysian Occupational Therapists National Conference
    • Related Report
      2021 Research-status Report
    • Int'l Joint Research
  • [Presentation] 非対面による認知機能および身体機能評価の有効性の検討(パイロットス タディ)2021

    • Author(s)
      望月美也子,長谷川昇,加藤真弓, 山田恭子, 清水暢子,
    • Organizer
      第64回日本老年医学会学術集会
    • Related Report
      2021 Research-status Report
  • [Presentation] Qualitative study on important elements of life for Japanese and Thai older adults2021

    • Author(s)
      Nobuko Shimizu, Nobuyuki Honda,Noboru Hasegawa,Takako Yamada, Miyako Mochizuki, Mayumi Kato
    • Organizer
      25th East Asia Forum of Nursing Scholars (EAFONS) Conference
    • Related Report
      2021 Research-status Report
    • Int'l Joint Research
  • [Presentation] 地域における健康高齢者の重要な生活行為 SCAT分析から 第2報2021

    • Author(s)
      山田恭子,坪内善仁・清水暢子・長谷川昇
    • Organizer
      第41回 近畿作業療法学会
    • Related Report
      2020 Research-status Report
  • [Presentation] 地域在住高齢者の血清ビタミンD濃度とQOLが 運動機能に及ぼす影響2021

    • Author(s)
      望月 美也子,長谷川 昇,加藤 真弓,清水 暢子,山田 恭子,本間 文子,吉武 将司,本多 伸行
    • Organizer
      第75回日本体力医学会大会
    • Related Report
      2020 Research-status Report
  • [Presentation] Relationship Between Cognitive Function and QOL in Communitydwelling Elderly: Focusing on Social Frailty2020

    • Author(s)
      Nobuyuki Honda, Noboru Hasegawa, Takako Yamada, Nobuko Shimizu, Miyako Mochizuki, Mayumi Kato
    • Organizer
      Malaysian Occupational Therapists National Conference 2021
    • Related Report
      2020 Research-status Report
    • Int'l Joint Research
  • [Presentation] タイ高齢者に学ぶ“老いることへの意味”についての研究 Study on " meaning to getting older " to learn from Thai elderly people2019

    • Author(s)
      清水暢子, 長谷川昇, 望月美也子, 加藤真弓, 山田恭子, Hunsa Sethabouppha, Chalinee Suwannanyos,
    • Organizer
      日本国際看護学会 第3回学術集会
    • Related Report
      2019 Research-status Report
  • [Presentation] Development of dementia predictor using near infrared spectroscopy-relationship between cerebral blood flow and cognitive function during dual-task.2019

    • Author(s)
      Nobuko Shimizu,Noboru Hasegawa,Miyako Mochizuki, Takako Yamada, Mayumi Kato, Masahiro Matsunaga, Tomohiro Umemura, Hunsa Sethabouppha, Nattaya Suwankruhasn, Chalinee Suvanayos, Duangruedee Lasuka
    • Organizer
      The 23rd East Asian Forum of Nursing Scholars (EAFONS) conference
    • Related Report
      2019 Research-status Report
    • Int'l Joint Research
  • [Presentation] 地域における健康高齢者の 重要な生活行為 SCAT分析 から ; パイロットスタデイ2019

    • Author(s)
      山田恭子,清水暢子,長谷川昇, 望月美也子, 加藤真弓
    • Organizer
      第7回 京都府作業療法学会
    • Related Report
      2019 Research-status Report
  • [Presentation] Relationship Between Cognitive Function And QOL In Community-dwelling Elderly: Focusing On Social Frailty2019

    • Author(s)
      Nobuyuki Honda, Noboru Hasegawa, Takako Yamada, Nobuko Shimizu, Miyako Motizuki, Myumi Katou
    • Organizer
      Malaysia OT national conference
    • Related Report
      2019 Research-status Report
    • Int'l Joint Research
  • [Remarks] Research Wisdom, Volume 7, April 2020

    • URL

      http://mis.nurse.cmu.ac.th/FlipPDF/ResearchWisdom_April2020/

    • Related Report
      2019 Research-status Report

URL: 

Published: 2017-04-28   Modified: 2025-01-30  

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