| Budget Amount *help |
¥4,160,000 (Direct Cost: ¥3,200,000、Indirect Cost: ¥960,000)
Fiscal Year 2019: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2018: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2017: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
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| Outline of Final Research Achievements |
We identified the bacteria responsible for equol production in soybean miso, and it was a bacterium of the genus Pediococcus. We identified the equol producing gene possessed by this bacteria, but we could not confirmed equol production by the enzyme isolated from this bacteria. In addition, equol prevented the development of bladder dysfunction in rats with bladder outlet obstruction. It was suggested that the mechanism involves not only an antioxidative effect but also a neuroprotective effect.
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