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Quantitative evaluation of vestibulo-ocular reflex in stroke patients and elucidation of brain activity during vestibular stimulation

Research Project

Project/Area Number 17K13055
Research Category

Grant-in-Aid for Young Scientists (B)

Allocation TypeMulti-year Fund
Research Field Rehabilitation science/Welfare engineering
Research InstitutionFukuoka International University of Health and Welfare (2019)
Saga University (2017-2018)

Principal Investigator

Mitsutake Tsubasa  福岡国際医療福祉大学, 医療学部, 講師 (00779712)

Project Period (FY) 2017-04-01 – 2020-03-31
Project Status Completed (Fiscal Year 2019)
Budget Amount *help
¥4,160,000 (Direct Cost: ¥3,200,000、Indirect Cost: ¥960,000)
Fiscal Year 2019: ¥260,000 (Direct Cost: ¥200,000、Indirect Cost: ¥60,000)
Fiscal Year 2018: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2017: ¥2,340,000 (Direct Cost: ¥1,800,000、Indirect Cost: ¥540,000)
Keywords脳卒中 / 前庭眼反射 / 歩行能力 / 姿勢制御 / 姿勢安定性 / 前庭脊髄反射 / 前庭リハビリテーション / 脳機能 / 前庭覚 / 加齢 / リハビリテーション / 脳神経疾患 / 神経科学
Outline of Final Research Achievements

The purpose of our study was to investigate the relationship between reflex function related to vestibular system and gait performance among patients with a post-stroke hemiparesis. As a result, a decrease in vestibulo-ocular reflex function post-stroke has an effect on gait performance in response to changing task demands. Regarding to rehabilitation tools, vestibular information focus on training could improve both the vestibulo-ocular reflex and gait performance in post-stroke patients. On the other hand, motor dysfunction of the hemiplegic lower extremity might lead to inhibition of normal standing postural stability. Decreased reflex function related to vestibular system could directly cause stranding postural instability during vestibular stimulation.

Academic Significance and Societal Importance of the Research Achievements

本研究は,末梢前庭障害患者や眩暈症状がなくても中枢神経障害によって前庭覚が関わる反射機能及び姿勢安定性が低下することを明らかにした.さらに,前庭覚に焦点を当てたトレーニングは前庭反射機能や応用的な歩行能力を改善する可能性を示した.これは転倒危険性が高い脳卒中患者に対して,前庭覚に着目した反射機能および身体機能評価の重要性を示すとともに,前庭リハビリテーションが転倒を予防するための一助となり得る可能性を明らかにした.

Report

(4 results)
  • 2019 Annual Research Report   Final Research Report ( PDF )
  • 2018 Research-status Report
  • 2017 Research-status Report
  • Research Products

    (23 results)

All 2019 2018 2017

All Journal Article (13 results) (of which Peer Reviewed: 13 results,  Open Access: 2 results) Presentation (10 results) (of which Invited: 4 results)

  • [Journal Article] Standing postural stability during galvanic vestibular stimulation is associated with the motor function of the hemiplegic lower extremity post-stroke2019

    • Author(s)
      Mitsutake Tsubasa、Sakamoto Maiko、Ueta Kozo、Horikawa Etsuo
    • Journal Title

      Topics in Stroke Rehabilitation

      Volume: 27 Issue: 2 Pages: 110-117

    • DOI

      10.1080/10749357.2019.1667662

    • Related Report
      2019 Annual Research Report
    • Peer Reviewed
  • [Journal Article] The effects of electromyography-triggered neuromuscular electrical stimulation plus tilt sensor functional electrical stimulation training on gait performance in patients with subacute stroke2019

    • Author(s)
      Mitsutake Tsubasa、Sakamoto Maiko、Horikawa Etsuo
    • Journal Title

      International Journal of Rehabilitation Research

      Volume: 42 Issue: 4 Pages: 358-364

    • DOI

      10.1097/mrr.0000000000000371

    • Related Report
      2019 Annual Research Report
    • Peer Reviewed
  • [Journal Article] <b>The relationship between modified clinical test of sensory interaction </b><b>and balance and galvanic body sway test </b>2018

    • Author(s)
      光武 翼、岡 真一郎、坂本 麻衣子、森田 義満、沖田 光紀、堀川 悦夫
    • Journal Title

      JAPANESE JOURNAL OF PHYSICAL THERAPY FUNDAMENTALS

      Volume: 21 Issue: 1 Pages: 95-100

    • DOI

      10.24780/jptf.21.1_95

    • NAID

      130007543819

    • ISSN
      2186-0742, 2434-0731
    • Year and Date
      2018-12-18
    • Related Report
      2018 Research-status Report
    • Peer Reviewed / Open Access
  • [Journal Article] Effects of the combination therapy of tilt sensor functional electrical stimulation and integrated volitional control electrical stimulation on brain activity during the subacute phase following stroke: a feasibility study2018

    • Author(s)
      Mitsutake Tsubasa、Sakamoto Maiko、Koyama Soichiro、Matsuda Kensuke、Okita Mitsunori、Horikawa Etsuo
    • Journal Title

      Journal of Physical Therapy Science

      Volume: 30 Issue: 12 Pages: 1412-1416

    • DOI

      10.1589/jpts.30.1412

    • NAID

      130007520372

    • ISSN
      0915-5287, 2187-5626
    • Related Report
      2018 Research-status Report
    • Peer Reviewed / Open Access
  • [Journal Article] A Trial Early Mobilization Program for Abdominal Aortic Aneurysm Replacement Surgery: Retrospective Study of Independent Ambulation, Complications and Hospital Days after Early Ambulation2018

    • Author(s)
      MORITA Yoshimitsu、KANEKO Hideo、MORITA Yuka、HIRATA Hirokatsu、MITSUTAKE Tsubasa、YOSHIMURA Kazuyo
    • Journal Title

      Rigakuryoho Kagaku

      Volume: 33 Issue: 4 Pages: 683-687

    • DOI

      10.1589/rika.33.683

    • NAID

      130007437483

    • ISSN
      1341-1667, 2434-2807
    • Related Report
      2018 Research-status Report
    • Peer Reviewed
  • [Journal Article] 右頭頂葉に対する経頭蓋直流電流刺激が立位姿勢調節に及ぼす影響2018

    • Author(s)
      岡真一郎,池田拓郎,後藤和彦,近藤遥奈,吉田誠也,光武翼,後藤純信
    • Journal Title

      理学療法科学

      Volume: ―

    • NAID

      130006727819

    • Related Report
      2017 Research-status Report
    • Peer Reviewed
  • [Journal Article] 女性前期高齢者におけるプレフレイルの関連要因の検討2018

    • Author(s)
      松田 憲亮, 池田 翔, 鶴 大輔, 永井 良治, 中原 雅美, 池田 拓郎, 光武 翼
    • Journal Title

      理学療法科学

      Volume: 33 Pages: 159-163

    • NAID

      130006415562

    • Related Report
      2017 Research-status Report
    • Peer Reviewed
  • [Journal Article] Transient Effects of Gaze Stability Exercises on Postural Stability in Patients With Posterior Circulation Stroke2017

    • Author(s)
      Mitsutake Tsubasa、Sakamoto Maiko、Ueta Kozo、Horikawa Etsuo
    • Journal Title

      J Mot Behav

      Volume: 21 Issue: 4 Pages: 1-6

    • DOI

      10.1080/00222895.2017.1367639

    • Related Report
      2017 Research-status Report
    • Peer Reviewed
  • [Journal Article] Poor gait performance is influenced with decreased vestibulo-ocular reflex in poststroke patients2017

    • Author(s)
      Mitsutake Tsubasa、Sakamoto Maiko、Ueta Kozo、Oka Shinichiro、Horikawa Etsuo
    • Journal Title

      Neuroreport

      Volume: 16;28(12) Issue: 12 Pages: 745-748

    • DOI

      10.1097/wnr.0000000000000841

    • Related Report
      2017 Research-status Report
    • Peer Reviewed
  • [Journal Article] Effects of vestibular rehabilitation on gait performance in poststroke patients: a pilot randomized controlled trial2017

    • Author(s)
      Mitsutake Tsubasa、Sakamoto Maiko、Ueta Kozo、Oka Shinichiro、Horikawa Etsuo
    • Journal Title

      Int J Rehabil Res

      Volume: 40(3) Issue: 3 Pages: 240-245

    • DOI

      10.1097/mrr.0000000000000234

    • Related Report
      2017 Research-status Report
    • Peer Reviewed
  • [Journal Article] 健常成人男性の胸背部に対する持続的圧迫刺激が軟部組織硬度,自律神経活動および手指皮膚温に与える影響2017

    • Author(s)
      岡真一郎,中元唯,池田拓郎,光武翼,濱地望
    • Journal Title

      徒手理学療法

      Volume: 17 Pages: 45-49

    • Related Report
      2017 Research-status Report
    • Peer Reviewed
  • [Journal Article] 入院期の心疾患患者における至適運動負荷量と左室拡張能および足関節上腕血圧比との関連2017

    • Author(s)
      森田義満,金子秀雄,岡真一郎,森田由佳,吉村和代,平田大勝,光武翼,井上健,横田大樹,稲毛智仁
    • Journal Title

      理学療法科学

      Volume: 32 Pages: 577-581

    • NAID

      130005988455

    • Related Report
      2017 Research-status Report
    • Peer Reviewed
  • [Journal Article] 動作分析の学生指導に関する臨床実習教育者の認識―計量テキスト分析を用いて―2017

    • Author(s)
      吉塚久記,玉利誠,本多裕一,光武翼,江越正次朗,大古場良太,浅見豊子
    • Journal Title

      理学療法科学

      Volume: 32 Pages: 497-501

    • NAID

      130005988475

    • Related Report
      2017 Research-status Report
    • Peer Reviewed
  • [Presentation] 前庭直流電気刺激時の脳活動領域とmodified Clinical Test of Sensory Interaction and Balanceの関連性 ~GVS-fMRI研究~2019

    • Author(s)
      光武翼、岡真一郎、平田大勝、堀川悦夫
    • Organizer
      第27回日本物理療法学会学術大会
    • Related Report
      2019 Annual Research Report
  • [Presentation] 物理療法機器を用いた歩行再学習2019

    • Author(s)
      光武翼
    • Organizer
      日本神経理学療法学会 第13回サテライトカンファレンス広島
    • Related Report
      2018 Research-status Report
    • Invited
  • [Presentation] 理学療法における運動療法と電気刺激療法の臨床応用2019

    • Author(s)
      光武翼
    • Organizer
      第17回島根県理学療法士学会
    • Related Report
      2018 Research-status Report
    • Invited
  • [Presentation] 左視床出血患者に対する随意運動介助型FESと傾斜センサ内蔵型FESの併用による脳活動領域の変化2018

    • Author(s)
      光武翼,小山総市朗,一ノ瀬和洋,中田祐治,沖田光紀,堀川悦夫
    • Organizer
      九州理学療法士・作業療法士合同学会2018 in 沖縄
    • Related Report
      2018 Research-status Report
  • [Presentation] 姿勢の違いが下肢への認知課題実施時の脳活動に及ぼす影響―座位・立位におけるfNIRSを用いた検証―2018

    • Author(s)
      一ノ瀬和洋、光武翼、中尾真理、黒木浩之
    • Organizer
      九州理学療法士・作業療法士合同学会2018 in 沖縄
    • Related Report
      2018 Research-status Report
  • [Presentation] 左片麻痺患者に対する経頭蓋直流電気刺激と機能的電気刺激の併用が歩行能力に及ぼす影響2018

    • Author(s)
      中田祐治、光武翼
    • Organizer
      九州理学療法士・作業療法士合同学会2018 in 沖縄
    • Related Report
      2018 Research-status Report
  • [Presentation] 脳画像の診方2018

    • Author(s)
      光武翼
    • Organizer
      佐賀県理学療法士協会主催 神経理学療法研修会
    • Related Report
      2018 Research-status Report
    • Invited
  • [Presentation] 脳卒中患者の前庭動眼反射と姿勢制御機能2018

    • Author(s)
      光武翼
    • Organizer
      第1回リハビリテーションのための姿勢運動制御研究会
    • Related Report
      2018 Research-status Report
    • Invited
  • [Presentation] 重度脳卒中片麻痺患者に対する後方からの歩行介助時の身体動揺―理学療法士と理学療法学科学生との比較検証―2017

    • Author(s)
      光武翼,中田祐治,岡真一郎,平田大勝,堀川悦夫
    • Organizer
      第52回日本理学療法学術大会
    • Related Report
      2017 Research-status Report
  • [Presentation] 脳卒中片麻痺患者の脳活動領域と歩行安定性に対する機能的電気刺激装置の併用による相乗効果―随意運動介助型電気刺激と傾斜センサ内蔵型電気刺激を用いた検証―2017

    • Author(s)
      光武翼,一ノ瀬和洋,小山総市朗,植田耕造,沖田光紀,堀川悦夫
    • Organizer
      第25回日本物理療法学会
    • Related Report
      2017 Research-status Report

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Published: 2017-04-28   Modified: 2021-02-19  

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