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The invention of transcranial direct current stimulation using homeostatic plasticity

Research Project

Project/Area Number 17K13073
Research Category

Grant-in-Aid for Young Scientists (B)

Allocation TypeMulti-year Fund
Research Field Rehabilitation science/Welfare engineering
Research InstitutionNiigata University of Health and Welfare

Principal Investigator

Miyaguchi Shota  新潟医療福祉大学, リハビリテーション学部, 助教 (60780343)

Project Period (FY) 2017-04-01 – 2019-03-31
Project Status Completed (Fiscal Year 2018)
Budget Amount *help
¥4,160,000 (Direct Cost: ¥3,200,000、Indirect Cost: ¥960,000)
Fiscal Year 2018: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Fiscal Year 2017: ¥2,470,000 (Direct Cost: ¥1,900,000、Indirect Cost: ¥570,000)
Keywords軽負荷反復運動 / 経頭蓋交流電流刺激 / 運動パフォーマンス / 一次運動野 / 小脳 / 基礎実験 / リハビリテーション / 神経科学 / 小脳半球 / 視覚追従課題 / 経頭蓋直流電流刺激 / Homeostatic plasticity / 経頭蓋磁気刺激 / 運動後抑制
Outline of Final Research Achievements

The purpose of this study was to examine whether or not the intervention effect that enhances the excitability of the primary motor area is enhanced during the excitability reduction period of the primary motor area that occurs after repetitive finger movement. As a result, when the peripheral nerve electrical stimulation to enhance the excitability of the primary motor area was applied after repetitive exercise, the excitability enhancing effect was lost. Next, we examined the optimal stimulation method for transcranial alternating current stimulation. As a result, it was revealed that stimulation to the primary motor area and cerebellum hemisphere (1 mA, 70 Hz, antiphase) improves motor performance. In the future, it is necessary to verify the combined effect with the repetitive exercise task using the stimulation method that was clarified this time.

Academic Significance and Societal Importance of the Research Achievements

本研究課題では,軽負荷の反復運動と電気刺激法の併用効果や,経頭蓋交流電流刺激による運動パフォーマンスへの効果が明らかになった.これらの研究成果は,一次運動野の可塑的変化および運動パフォーマンスの向上を促す最適な介入方法を明らかにするための基礎的な知見となり得る.

Report

(3 results)
  • 2018 Annual Research Report   Final Research Report ( PDF )
  • 2017 Research-status Report
  • Research Products

    (7 results)

All 2019 2018 2017

All Journal Article (3 results) (of which Peer Reviewed: 3 results,  Open Access: 1 results) Presentation (4 results)

  • [Journal Article] Gamma tACS over M1 and cerebellar hemisphere improves motor performance in a phase-specific manner2019

    • Author(s)
      Miyaguchi Shota、Otsuru Naofumi、Kojima Sho、Yokota Hirotake、Saito Kei、Inukai Yasuto、Onishi Hideaki
    • Journal Title

      Neuroscience Letters

      Volume: 694 Pages: 64-68

    • DOI

      10.1016/j.neulet.2018.11.015

    • Related Report
      2018 Annual Research Report
    • Peer Reviewed
  • [Journal Article] The effect of gamma tACS over the M1 region and cerebellar hemisphere does not depend on current intensity2019

    • Author(s)
      Miyaguchi Shota、Otsuru Naofumi、Kojima Sho、Yokota Hirotake、Saito Kei、Inukai Yasuto、Onishi Hideaki
    • Journal Title

      Journal of Clinical Neuroscience

      Volume: - Pages: 54-58

    • DOI

      10.1016/j.jocn.2019.03.045

    • Related Report
      2018 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Transcranial Alternating Current Stimulation With Gamma Oscillations Over the Primary Motor Cortex and Cerebellar Hemisphere Improved Visuomotor Performance2018

    • Author(s)
      Miyaguchi Shota、Otsuru Naofumi、Kojima Sho、Saito Kei、Inukai Yasuto、Masaki Mitsuhiro、Onishi Hideaki
    • Journal Title

      Frontiers in Behavioral Neuroscience

      Volume: 12 Pages: 132-132

    • DOI

      10.3389/fnbeh.2018.00132

    • Related Report
      2018 Annual Research Report
    • Peer Reviewed / Open Access
  • [Presentation] 経頭蓋交流電流刺激介入中の運動遂行機能の変化‐位相特異性の検証‐2018

    • Author(s)
      124.宮口翔太,小島 翔,齊藤 慧,横田裕丈,犬飼康人,大鶴直史,大西秀明.
    • Organizer
      第48回日本臨床神経生理学会
    • Related Report
      2018 Annual Research Report
  • [Presentation] M1および小脳への経頭蓋交流電流刺激中の運動遂行能力の変化‐電流強度の検討‐2018

    • Author(s)
      宮口翔太
    • Organizer
      第23回日本基礎理学療法学会学術大会
    • Related Report
      2018 Annual Research Report
  • [Presentation] 経頭蓋交流電流刺激介入中の運動遂行機能の変化2017

    • Author(s)
      宮口翔太、小島 翔、立木翔太、齊藤 慧、犬飼康人、正木光裕、大鶴直史、大西秀明
    • Organizer
      第47回日本臨床神経生理学会
    • Related Report
      2017 Research-status Report
  • [Presentation] 経頭蓋交流電流刺激を用いた皮質間ネットワークの強化が運動遂行能力に与える効果2017

    • Author(s)
      宮口翔太、小島 翔、立木翔太、齊藤 慧、犬飼康人、正木光裕、大鶴直史、大西秀明
    • Organizer
      第17回新潟医療福祉学会
    • Related Report
      2017 Research-status Report

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Published: 2017-04-28   Modified: 2020-03-30  

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