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Investigation of the clinical condition of pusher behavior after stroke and the effect of galvanic vestibular stimulation

Research Project

Project/Area Number 17K13081
Research Category

Grant-in-Aid for Young Scientists (B)

Allocation TypeMulti-year Fund
Research Field Rehabilitation science/Welfare engineering
Research InstitutionKio University

Principal Investigator

Nakamura Junji  畿央大学, 健康科学部, 研究員 (30793723)

Project Period (FY) 2017-04-01 – 2020-03-31
Project Status Completed (Fiscal Year 2019)
Budget Amount *help
¥3,380,000 (Direct Cost: ¥2,600,000、Indirect Cost: ¥780,000)
Fiscal Year 2019: ¥390,000 (Direct Cost: ¥300,000、Indirect Cost: ¥90,000)
Fiscal Year 2018: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Fiscal Year 2017: ¥2,340,000 (Direct Cost: ¥1,800,000、Indirect Cost: ¥540,000)
KeywordsPusher現象 / 脳卒中 / リハビリテーション / 電気刺激 / 前庭機能 / 前庭脊髄路 / 前提機能
Outline of Final Research Achievements

The purpose of this study were to investigate the relationship between the Pushing Behavior(PB) and the vestibulospinal tract, and the immediate effect of the GVS on the PB. In addition, we also investigated the reliability and validity of the assessment for vestibulospinal tract function using the H-reflex, and the characteristics of subjective postural vertical(SPV) used for assessment of PB. The assessment of vestibulospinal tract function showed sufficient reliability and validity in healthy subjects. The characteristics of SPV showed that the somatosensory information from the seat plays an important role. In PB patients, there were cases in which abnormal vestibulospinal tract function was suspected. In some cases, GVS caused immediate improvement of the PB. It was suggested that GVS could be an intervention tool for PB.

Academic Significance and Societal Importance of the Research Achievements

本研究では、直流前庭電気刺激(GVS)を用いた前庭脊髄路機能評価の妥当性、再現性を明らかにし、PBの検査で用いられるSPVの測定特性を明らかにすることができた。これらは、国内外初の知見であり、前庭脊髄路機能評価の臨床応用やPBの病態を明らかにする上で、その意義は大きい。PBにおいて前庭脊髄路機能の異常やGVSによるPBの即時的改善が一部の症例でみられた。これらはPBの病態解明および治療手段の開発のために重要な知見であると考えられる。

Report

(4 results)
  • 2019 Annual Research Report   Final Research Report ( PDF )
  • 2018 Research-status Report
  • 2017 Research-status Report
  • Research Products

    (7 results)

All 2019 2018

All Journal Article (2 results) (of which Peer Reviewed: 2 results) Presentation (5 results)

  • [Journal Article] Role of somatosensory and/or vestibular sensory information in subjective postural vertical in healthy adults2019

    • Author(s)
      Nakamura J, Shiozaki T, Tsujimoto N, Ikuno K, Okada Y, Shomoto K
    • Journal Title

      Neurosci Lett

      Volume: 714 Pages: 134598-134598

    • DOI

      10.1016/j.neulet.2019.134598

    • Related Report
      2019 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Influence of the intensity of galvanic vestibular stimulation and cutaneous stimulation on the soleus H-reflex in healthy individuals.2018

    • Author(s)
      Okada Y, Shiozaki T, Nakamura J, Azumi Y, Inazato M, Ono M, Kondo H, Sugitani M, Matsugi A.
    • Journal Title

      Neuroreport

      Volume: 5 Issue: 13 Pages: 1135-1139

    • DOI

      10.1097/wnr.0000000000001086

    • Related Report
      2018 Research-status Report
    • Peer Reviewed
  • [Presentation] 直流前庭電気刺激を利用した前庭脊髄路の機能評価の再現性と左右差の検証2019

    • Author(s)
      中村潤二, 塩崎智之, 田中宏明, 植田耕造, 生野公貴, 岡田洋平
    • Organizer
      第17回日本神経理学療法学会学術大会
    • Related Report
      2019 Annual Research Report
  • [Presentation] 直流前庭電気刺激を利用した前庭脊髄路の機能評価の左右差と利き足の影響の検証2019

    • Author(s)
      中村潤二, 塩崎智之, 田中宏明, 植田耕造, 生野公貴, 岡田洋平, 庄本康治
    • Organizer
      第27回日本物理療法学会学術大会
    • Related Report
      2019 Annual Research Report
  • [Presentation] 体性感覚情報や前庭感覚情報の変調 が主観的身体垂直に与える影響2018

    • Author(s)
      中村潤二, 辻本直秀, 藤井慎太郎, 塩崎智之, 生野公貴, 岡田 洋平, 庄本 康治
    • Organizer
      第26回日本物理療法学会学術大会
    • Related Report
      2018 Research-status Report
  • [Presentation] 座面からの体性感覚情報の違いが主観的身体垂直に及ぼす影響2018

    • Author(s)
      中村潤二, 辻本直秀, 藤井慎太郎, 塩崎智之, 生野公貴
    • Organizer
      第16回日本神経理学療法学会学術大会
    • Related Report
      2018 Research-status Report
  • [Presentation] 体性感覚情報や前庭感覚情報の変調が主観的身体垂直に与える影響2018

    • Author(s)
      中村潤二, 辻本直秀, 藤井慎太郎, 塩崎智之, 岡田洋平, 庄本康治
    • Organizer
      第1回リハビリテーションのための姿勢運動制御研究会
    • Related Report
      2018 Research-status Report

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Published: 2017-04-28   Modified: 2021-02-19  

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