| Project/Area Number |
17K14139
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Multi-year Fund |
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| Research Field |
Quantum beam science
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| Research Institution | National Institutes for Quantum and Radiological Science and Technology |
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Principal Investigator |
Katagiri Ken 国立研究開発法人量子科学技術研究開発機構, 放射線医学総合研究所 加速器工学部, 主任研究員(定常) (90510868)
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| Research Collaborator |
Nagatsu Kotaro
Koba Yusuke
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| Project Period (FY) |
2017-04-01 – 2019-03-31
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| Project Status |
Completed (Fiscal Year 2018)
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| Budget Amount *help |
¥4,420,000 (Direct Cost: ¥3,400,000、Indirect Cost: ¥1,020,000)
Fiscal Year 2018: ¥260,000 (Direct Cost: ¥200,000、Indirect Cost: ¥60,000)
Fiscal Year 2017: ¥4,160,000 (Direct Cost: ¥3,200,000、Indirect Cost: ¥960,000)
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| Keywords | ISOL / イオン源 / 重粒子線がん治療 / RIビーム |
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| Outline of Final Research Achievements |
The purpose of this study is to investigate the feasibility of the production of pulsed C-11 ions for heavy-ion cancer therapy by the on-line 11C+ ion production experiment. We carried out the improvement/optimization and the performance investigation of the 11C molecule production/separation system (CMPS) and singly-charged ion source (SCIS). We also carried out the development a target box for proton irradiation and a new water-cooled gas-less beam window for the proton irradiation. Moreover, a safety interlock and control system have been constructed for procedures in C-11 ion production. The construction of the 11C+ ion production system including these modules has been finally finished, the on-line experiment is scheduled to be started in the first half year of 2019.
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| Academic Significance and Societal Importance of the Research Achievements |
本技術が実現し，11Cイオンビームによる治療が可能となれば，重粒子線治療の際に体内の照射位置/線量分布をリアルタイムに検証することが可能となる．この情報を用いれば，例えば患者の呼吸と共に移動する臓器に合わせてビームの照射位置を動的に制御することができ，さらに高い精度で照射を行うことが可能となる．したがって，この画期的な技術が実現すれば，身体的負担をさらに減らす事ができ，患者のQOLはさらに向上する．
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