| Budget Amount *help |
¥4,290,000 (Direct Cost: ¥3,300,000、Indirect Cost: ¥990,000)
Fiscal Year 2019: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2018: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2017: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
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| Outline of Final Research Achievements |
A conventional taste sensor is a measurement system that detects the interaction between taste substances and lipid polymer membranes by a batch method. In this study, we developed a flow-injection type taste sensor to add time resolution for interaction detection. Furthermore, the interaction between lipids used in lipid polymer membranes and taste substances was investigated by molecular simulation, and the relationship with the sensor response was discussed. It was shown that the fabricated flow-injection taste sensor can measure the time-dependent change in the membrane potential for a taste substance with high hydrophobicity and is capable of measuring the time-dependent change in the interaction. In addition, there is a possibility that the interaction between lipids and taste substances can be predicted by molecular simulation, and further improvement of taste sensors can be expected.
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