| Budget Amount *help |
¥4,420,000 (Direct Cost: ¥3,400,000、Indirect Cost: ¥1,020,000)
Fiscal Year 2019: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2018: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2017: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
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| Outline of Final Research Achievements |
Vertebrate rod and cone photoreceptors are responsible for scotopic and photopic vision, respectively. The light sensitivity and kinetics of there photoreceptors differ depending on their vison. The relationship between photoresponse properties and the phototransduction pathways and morphology in both photoreceptor cells remains unclear. To clarify this, we have created mouse models in which phototransduction molecules in rods are replaced with red cone opsin. In addition, the spatial model of photoreceptor cells revealed that the differences in photoreceptor morphology are involved in the photoresponse characteristics.
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