| Budget Amount *help |
¥4,420,000 (Direct Cost: ¥3,400,000、Indirect Cost: ¥1,020,000)
Fiscal Year 2019: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2018: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
Fiscal Year 2017: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
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| Outline of Final Research Achievements |
I analyzed the physiological functions of neuropeptides or neurotransmitters released from terminal nerve gonadotropin-releasing hormone 3 (TN-GnRH3) neurons, which play an important role in sensory recognition and behaviors. To examine firing activities and neuropeptide/neurotransmitter release, I recorded activities of GFP-labeled TN-GnRH3 neurons in medaka by whole cell patch clamp and Ca2+ imaging. My results suggested that synaptic inputs of glutamate induce neuropeptide release from TN-GnRH3 neurons. In addition, behavioral analyses demonstrated that biomolecules released from TN-GnRH3 neurons modulate animal behaviors.
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