The process of hybridization and its consequence on phenotypic diversity in primates

• Project/Area Number: 17K15195
• Research Category: Grant-in-Aid for Young Scientists (B)
• Allocation Type: Multi-year Fund
• Research Field: Ecology/Environment
• Research Institution: Kyoto University
• Principal Investigator: Ito Tsuyoshi 京都大学, 霊長類研究所, 助教 (20711485)
• Research Collaborator: MALAIVIJITNOND Suchinda ; KANTHASWAMY Sreetharan ; BUNLUNGSUP Srichan ; OLDT Robert ; HAMADA Yuzuru
• Project Period (FY): 2017-04-01 – 2019-03-31
• Project Status: Completed (Fiscal Year 2018)
• Budget Amount: ¥4,550,000 (Direct Cost: ¥3,500,000、Indirect Cost: ¥1,050,000); Fiscal Year 2018: ¥2,340,000 (Direct Cost: ¥1,800,000、Indirect Cost: ¥540,000); Fiscal Year 2017: ¥2,210,000 (Direct Cost: ¥1,700,000、Indirect Cost: ¥510,000)
• Keywords: 遺伝子浸透 / マカクザル / 形態 / 東南アジア / 生殖隔離 / 交雑帯 / RAD-Seq / エコゲノミクス

Outline of Final Research Achievements

This study performed population genomics to estimate when and how the hybrid zone between rhesus and long-tailed macaques has been formed in Southeast Asia. Results suggest that the two species recently contacted to each other and formed hybrid zone, after long-time isolation. Some loci, particularly on X-chromosome, show abrupt change in allele frequency at the traditionally recognized species boundary. In contrast, in a handful of loci, rhesus macaque-type alleles were likely introgressed widely into the long-tailed macaque populations across the Isthmus of Kra possibly because of natural selection.

Academic Significance and Societal Importance of the Research Achievements

交雑帯の多地域のサンプルを対象にゲノムレベルでの解析を達成した本研究は、従来研究よりも詳細にアカゲザルとカニクイザルの交雑過程と遺伝子浸透のパターンを推定することができた。この成果は、ヒトを含めた霊長類の交雑とその帰結、生殖隔離と種分化のメカニズムを理解する上で役に立つと期待される。また、本研究で明らかにしたインドシナ半島の地域集団の集団構造と遺伝的多様性は、それらの保全の上でも重要な情報となる。

Research Products

• [Int'l Joint Research] Chulalongkorn University(タイ)
• [Int'l Joint Research] Arizona State University(米国)
• [Int'l Joint Research] Chulalongkorn University(タイ)
• [Int'l Joint Research] Arizona State University(米国)
• [Journal Article] Biogeographic variation in skull morphology across the Kra Isthmus in dusky leaf monkeys (2018)
  • Author(s): Ito T, Koyabu D（印刷中）
  • Journal Title: Journal of Zoological Systematics and Evolutionary Research Volume: －
  • NAID: 120006715529
  • Peer Reviewed
• [Presentation] Incongruence between nuclear genome phylogeny and morphological diversity in Japanese macaques (2019)
  • Author(s): Ito T, Hayakawa T, Suzuki-Hashido N, Hamada Y, Kurihara Y, Hanya G, Kaneko A, Natsume T, Aisu S, Honda T, Yachimori S, Anezaki T, Shintaku Y, Omi T, Hayama S, Imai H, Wakamori H, Tanaka M, Kawamoto Y
  • Organizer: The 63rd Primates Conference