| Budget Amount *help |
¥4,290,000 (Direct Cost: ¥3,300,000、Indirect Cost: ¥990,000)
Fiscal Year 2019: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2018: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2017: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
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| Outline of Final Research Achievements |
(1) A single-step synthesis of azosulfone from primary aromatic amines was developed with the combined use of dirhodium(II) complex catalysts and iminoiodinane. The obtained azosulfones were successfully demonstrated to serve as potent stable surrogates for diazonium salts in aromatic C-N bond transformations.
(2) 2-Aminophenylboronates were found to generate benzynes under the above described conditions using Rh(II)-nitrene.
(3) Using N,N-dialkylanilines as the substrate, aromatic C-H amination with Rh(II)-nitrene species was developed. The reaction selectively proceeded at the ortho position of extremely bulky dialkylamino group.
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