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Understanding of NTM dynamics in environments

Research Project

Project/Area Number 17K15490
Research Category

Grant-in-Aid for Young Scientists (B)

Allocation TypeMulti-year Fund
Research Field Environmental and hygienic pharmacy
Research InstitutionOsaka Shoin Women's University (2019)
Osaka University (2017-2018)

Principal Investigator

Ichijo Tomoaki  大阪樟蔭女子大学, 健康栄養学部, 准教授 (20513899)

Project Period (FY) 2017-04-01 – 2020-03-31
Project Status Completed (Fiscal Year 2019)
Budget Amount *help
¥4,160,000 (Direct Cost: ¥3,200,000、Indirect Cost: ¥960,000)
Fiscal Year 2018: ¥2,600,000 (Direct Cost: ¥2,000,000、Indirect Cost: ¥600,000)
Fiscal Year 2017: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Keywords環境微生物 / 環境疾患 / 非結核性抗酸菌
Outline of Final Research Achievements

In order to prevent the nontuberculous mycobacterial diseases originated from environments, clarification of the dynamics of nontuberculous mycobacteria in the environment is indispensable. In this study, we focused on the soil considered as one of infectious sources, and clarified the mycobacterial abundance and community structure using gene-targeting methods.
We found that there were various species of nontuberculous mycobacteria in the environment. Among these, focusing on Mycobacterium avium, it was found that it existed widely in the soil analyzed in this study, and it might dominate in the environment that repeats drying and wetting like flower pots.
These results became the fundamental knowledge for understanding the dynamics of nontuberculous mycobacteria in the environment, and we can contribute to prevent the nontuberculous mycobacterial diseases from the viewpoint of environmental microbiology.

Academic Significance and Societal Importance of the Research Achievements

得られた結果は、環境における非結核性抗酸菌の動態を理解するための基盤的知見となり、環境微生物学の観点から非結核性抗酸菌症の予防への貢献が可能となる。

Report

(4 results)
  • 2019 Annual Research Report   Final Research Report ( PDF )
  • 2018 Research-status Report
  • 2017 Research-status Report
  • Research Products

    (1 results)

All 2019

All Journal Article (1 results) (of which Int'l Joint Research: 1 results,  Peer Reviewed: 1 results,  Open Access: 1 results)

  • [Journal Article] Genetic relatedness of Mycobacterium avium subsp. hominissuis isolates from bathrooms of healthy volunteers, rivers, and soils in Japan with human clinical isolates from different geographical areas2019

    • Author(s)
      Arikawa Kentaro、Ichijo Tomoaki、Nakajima Satomi、Nishiuchi Yukiko、Yano Hirokazu、Tamaru Aki、Yoshida Shiomi、Maruyama Fumito、Ota Atsushi、Nasu Masao、Starkova Daria A.、Mokrousov Igor、Narvskaya Olga V.、Iwamoto Tomotada
    • Journal Title

      Infection, Genetics and Evolution

      Volume: 74 Pages: 103923-103923

    • DOI

      10.1016/j.meegid.2019.103923

    • Related Report
      2019 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research

URL: 

Published: 2017-04-28   Modified: 2021-02-19  

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