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Development of flexible localization system designed to optimize patient positioning reproducibility in radiotherapy

Research Project

Project/Area Number 17K15803
Research Category

Grant-in-Aid for Young Scientists (B)

Allocation TypeMulti-year Fund
Research Field Medical Physics and Radiological Technology
Research InstitutionKobe University

Principal Investigator

Uehara Kazuyuki  神戸大学, 医学研究科, 医学研究員 (80582006)

Project Period (FY) 2017-04-01 – 2019-03-31
Project Status Completed (Fiscal Year 2018)
Budget Amount *help
¥2,210,000 (Direct Cost: ¥1,700,000、Indirect Cost: ¥510,000)
Fiscal Year 2018: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2017: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Keywords放射線治療 / 画像誘導放射線治療 / 位置照合 / 距離画像 / RGB画像
Outline of Final Research Achievements

The purpose of this study was to develop a flexible patient setup system for the improving of patient positioning reproducibility, imaging dose, and setup time in image-guided radiation therapy. We analyzed the residual setup error in the existing method and clarified the impacts on the radiation dose distribution.The feasibility of our system was evaluated by the patient positioning unit prototyped using commercial immobilization devices. The results in this study has found additional challenges to make the device more flexible.

Academic Significance and Societal Importance of the Research Achievements

本研究において現状実施されている皮膚マーキングとレーザー照合機による体軸補正、それに続けて一回から複数回のX線画像による照合で再現される体位において補正しきれていない残余誤差について評価した。またその残余誤差が線量分布、特にリスク臓器に及ぼす影響について評価した。この結果が本研究の開発要素が目指すべき基準となると考えられる。フレキシブルな患者位置照合システムの開発では体位の側屈に対する補正についての構造的課題や専用のコンプレッサの必要性が認められた。これらの課題をクリアすることで画像誘導放射線治療において患者被ばく線量の低減や照合時間の短縮が可能となると考えられる。

Report

(3 results)
  • 2018 Annual Research Report   Final Research Report ( PDF )
  • 2017 Research-status Report
  • Research Products

    (4 results)

All 2019 2018 2017

All Journal Article (2 results) (of which Int'l Joint Research: 1 results,  Peer Reviewed: 2 results,  Open Access: 1 results) Presentation (2 results) (of which Int'l Joint Research: 1 results)

  • [Journal Article] Clinical log data analysis for assessing the accuracy of the CyberKnife fiducial-free lung tumor tracking system2018

    • Author(s)
      Nakayama Masao、Nishimura Hideki、Mayahara Hiroshi、Nakamura Masaki、Uehara Kazuyuki、Tsudou Shinji、Harada Aya、Akasaka Hiroaki、Sasaki Ryohei
    • Journal Title

      Practical Radiation Oncology

      Volume: 8 Issue: 2 Pages: 63-70

    • DOI

      10.1016/j.prro.2017.10.014

    • NAID

      120006873065

    • Related Report
      2017 Research-status Report
    • Peer Reviewed / Open Access
  • [Journal Article] Identification of the suitable leaf margin for liver stereotactic body radiotherapy with flattening filter-free beams2017

    • Author(s)
      Ogata T, Nishimura H, Mayahara H, Uehara K, Okayama T.
    • Journal Title

      Medical dosimetry

      Volume: 42 Issue: 4 Pages: 268-272

    • DOI

      10.1016/j.meddos.2017.06.002

    • Related Report
      2017 Research-status Report
    • Peer Reviewed / Int'l Joint Research
  • [Presentation] ヘリカル式強度変調放射線治療におけるMLC latencyモデルの評価手法の検討2019

    • Author(s)
      上原和之、溝延数房、沖裕也、王天縁、西村英輝、馬屋原博、原田文、門脇伸行、佐々木良平
    • Organizer
      第32回高精度放射線外部照射部会学術大会
    • Related Report
      2018 Annual Research Report
  • [Presentation] Assessment of Clinical Accuracy of the CyberKnife Fiducial-Free Lung Tumor Tracking System2017

    • Author(s)
      M Nakayama, K Uehara , S Tsudou , S Tamura , H Nishimura , H Mayahara , R Sasaki
    • Organizer
      American Association of Physicists in Medicine 59th Annual Meeting & Exhibition
    • Related Report
      2017 Research-status Report
    • Int'l Joint Research

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Published: 2017-04-28   Modified: 2020-03-30  

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