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Integrated database of tumor and radiation dose information for building big data in cancer treatment

Research Project

Project/Area Number 17K15817
Research Category

Grant-in-Aid for Young Scientists (B)

Allocation TypeMulti-year Fund
Research Field Medical Physics and Radiological Technology
Research InstitutionOsaka International Cancer Institute

Principal Investigator

Ueda Yoshihiro  地方独立行政法人大阪府立病院機構大阪国際がんセンター(研究所), その他部局等, 放射線腫瘍科技師 (80643486)

Project Period (FY) 2017-04-01 – 2021-03-31
Project Status Completed (Fiscal Year 2020)
Budget Amount *help
¥3,900,000 (Direct Cost: ¥3,000,000、Indirect Cost: ¥900,000)
Fiscal Year 2019: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000)
Fiscal Year 2018: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000)
Fiscal Year 2017: ¥2,340,000 (Direct Cost: ¥1,800,000、Indirect Cost: ¥540,000)
KeywordsData base / Big data / Dose volume histogram / Treatment Planning / NTCP / TCP / Treatment planning / RapidPlan / VMAT / Knowledge-based planning / 高精度放射線治療 / 人工知能 / Knoweldge-based planning / data base / dose volume histogram / Organ Dose / DVH / ビッグデータ / 腫瘍 / 患者情報 / データベース
Outline of Final Research Achievements

We built a database to store dose information, stored dose information for clinical plans, which enabled us to analyze a lot of information at once. By comparing the dose information, we constructed a model to calculate the cardiac dose of breast tangential irradiation from the irradiation image. We also evaluated the optimal dose division for irradiation of stage III non-small cell lung cancer. Furthermore, for the probability of treatment planning method using artificial intelligence technology, a system for analyzing dose information was utilized.

Academic Significance and Societal Importance of the Research Achievements

臨床データを格納するデータベースは現場で臨床応用されているが、線量・腫瘍情報を格納できるデータベースシステムは発展途上である。本研究ではこれらの情報を臨床データと結び付けることで、有効であることを証明できた。さらに今後医療業界で発展が期待される人工知能を用いた治療システムを用いた手法を確立するためにも本データベースは力を発揮した。本研究成果は今後の放射線治療の発展のために不可欠である。

Report

(5 results)
  • 2020 Annual Research Report   Final Research Report ( PDF )
  • 2019 Research-status Report
  • 2018 Research-status Report
  • 2017 Research-status Report
  • Research Products

    (16 results)

All 2020 2019 2018 2017 Other

All Int'l Joint Research (1 results) Journal Article (8 results) (of which Int'l Joint Research: 1 results,  Peer Reviewed: 6 results,  Open Access: 4 results) Presentation (7 results) (of which Int'l Joint Research: 3 results)

  • [Int'l Joint Research] NYU Health & Laura and Isaac PCC(米国)

    • Related Report
      2018 Research-status Report
  • [Journal Article] Novel strategy with the automatic non-coplanar volumetric-modulated arc therapy for angiosarcoma of the scalp2020

    • Author(s)
      Inui Shoki、Ueda Yoshihiro、Ohira Shingo、Tsuru Haruhi、Isono Masaru、Miyazaki Masayoshi、Koizumi Masahiko、Teshima Teruki
    • Journal Title

      Radiation Oncology

      Volume: 15 Issue: 1 Pages: 175-175

    • DOI

      10.1186/s13014-020-01614-3

    • Related Report
      2020 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Characterization of knowledge-based volumetric modulated arc therapy plans created by three different institutions' models for prostate cancer2020

    • Author(s)
      Yoshihiro Ueda, Hajime Monzen, Jun-Ichi Fukunaga, Shingo Ohira, Mikoto Tamura, Osamu Suzuki, Shoki Inui, Masaru Isono, Masayoshi Miyazaki, Iori Sumida, Kazuhiko Ogawa, Teruki Teshima
    • Journal Title

      Reports of Practical Oncology and Radiotherapy

      Volume: 25(6) Issue: 6 Pages: 1023-1028

    • DOI

      10.1016/j.rpor.2020.08.011

    • Related Report
      2020 Annual Research Report
    • Peer Reviewed
  • [Journal Article] The Promising Treatment Schedule of Concurrent Chemoradiotherapy for Stage III Non-small Cell Lung Cancer: Alternative for Conventional Fractionation Using Mathematical Analysis2020

    • Author(s)
      Ueda Y, Suzuki O, Ohira S, Yagi M, Sumida I, Wada K, Inui S, Isono M, Miyazaki M, Ogawa K and Teshima T
    • Journal Title

      Anticancer Res

      Volume: 40 Issue: 7 Pages: 4095-4104

    • DOI

      10.21873/anticanres.14408

    • Related Report
      2020 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Knowledge-based planning for oesophageal cancers using a model trained with plans from a different treatment planning system2019

    • Author(s)
      Ueda Yoshihiro、Miyazaki Masayoshi、Sumida Iori、Ohira Shingo、Tamura Mikoto、Monzen Hajime、Tsuru Haruhi、Inui Shoki、Isono Masaru、Ogawa Kazuhiko、Teshima Teruki
    • Journal Title

      Acta Oncologica

      Volume: 59 Issue: 3 Pages: 274-283

    • DOI

      10.1080/0284186x.2019.1691257

    • Related Report
      2019 Research-status Report
    • Peer Reviewed
  • [Journal Article] Questionnaire survey on treatment planning techniques for lung stereotactic body radiotherapy in Japan2019

    • Author(s)
      Ueda Yoshihiro、Takakura Toru、Ota Seiichi、Kito Satoshi、Sasaki Koji、Shimizu Hidetoshi、Tatsumi Daisaku、Yano Shinsuke、Nakamura Mitsuhiro
    • Journal Title

      Journal of Radiation Research

      Volume: 61 Issue: 1 Pages: 104-116

    • DOI

      10.1093/jrr/rrz081

    • Related Report
      2019 Research-status Report
  • [Journal Article] Comparison of interfractional setup reproducibility between two types of patient immobilization devices in image-guided radiation therapy for prostate cancer2018

    • Author(s)
      Ueda Yoshihiro、Inui Shoki、Ohira Shingo、Isono Masaru、Masaoka Akira、Murata Seiya、Nitta Yuya、Karino Tsukasa、Miyazaki Masayoshi、Teshima Teruki
    • Journal Title

      Journal of Medical Physics

      Volume: 43 Issue: 4 Pages: 230-230

    • DOI

      10.4103/jmp.jmp_20_18

    • Related Report
      2018 Research-status Report
    • Peer Reviewed / Open Access
  • [Journal Article] Evaluation of multiple institutions’ models for knowledge-based planning of volumetric modulated arc therapy (VMAT) for prostate cancer2018

    • Author(s)
      Ueda Yoshihiro、Fukunaga Jun-ichi、Kamima Tatsuya、Adachi Yumiko、Nakamatsu Kiyoshi、Monzen Hajime
    • Journal Title

      Radiation Oncology

      Volume: 13 Issue: 1 Pages: 1-11

    • DOI

      10.1186/s13014-018-0994-1

    • Related Report
      2018 Research-status Report 2017 Research-status Report
    • Peer Reviewed / Open Access
  • [Journal Article] Model-based cardiac dose estimation in radiation treatment of left breast cancer2018

    • Author(s)
      Ueda Yoshihiro、Gerber Naamit K、Das Indra J
    • Journal Title

      The British Journal of Radiology

      Volume: 91 Issue: 1090 Pages: 1-10

    • DOI

      10.1259/bjr.20180287

    • Related Report
      2018 Research-status Report
    • Int'l Joint Research
  • [Presentation] Knowledge-based volume modulated arc therapy planning for esophageal cancers using a model trained with plans optimized by RayStation2019

    • Author(s)
      Ueda Yoshihiro、Miyazaki Masayoshi、Ohira Shingo、Tamura Mikoto、Monzen Hajime、Tsuru Haruhi、Inui Shoki、Isono Masaru、Teshima Teruki
    • Organizer
      Engineering and Physical Sciences in Medicine Conference and Asia-Oceania Congress of Medical Physics 2019
    • Related Report
      2019 Research-status Report
    • Int'l Joint Research
  • [Presentation] TCP/NTCPを用いたIII期非小細胞肺がんに対する 化学放射線治療の照射スケジュールの検討2018

    • Author(s)
      上田悦弘 鈴木修 八木雅史 大平新吾 五十野優 乾翔輝 和田健太郎 宮崎正義 隅田伊織 小川和彦 手島昭樹
    • Organizer
      高精度放射線外部照射部会学術大会
    • Related Report
      2018 Research-status Report
  • [Presentation] TCP/NTCPを用いたIII期非小細胞肺がんに対する 化学放射線治療の照射スケジュールの検討2018

    • Author(s)
      上田悦弘、鈴木修、八木雅史、大平新吾、五十野優、乾翔輝、和田健太郎、宮崎正義、隅田伊織、小川和彦、手島昭樹
    • Organizer
      第31回高精度放射線外部照射部会学術大会
    • Related Report
      2017 Research-status Report
  • [Presentation] Evaluation for knowledge based planning of volumetric modulated arc therapy (VMAT) for prostate cancer in multi-institution2018

    • Author(s)
      Yoshihiro Ueda, Jun-ichi Fukunaga, Tatsuya Kamima, Yumiko Adachi, Kiyoshi Nakamatsu, Hajime Monzen
    • Organizer
      第115回日本医学物理学会学術学会
    • Related Report
      2017 Research-status Report
  • [Presentation] Multi-institutional analysis for knowledge based planning of volumetric modulated arc therapy for prostate cancer2018

    • Author(s)
      Yoshihiro Ueda, Jun-ichi Fukunaga, Tatsuya Kamima, Yumiko Adachi, Kiyoshi Nakamatsu, Hajime Monzen
    • Organizer
      World Congress on Medical Physics & Biomedical Engeineering
    • Related Report
      2017 Research-status Report
    • Int'l Joint Research
  • [Presentation] The simulation of the tumor control and the normal tissue complications in accelerated radiotherapy for stage III non-small cell lung cancer2017

    • Author(s)
      Yoshihiro Ueda, Osamu Suzuki, Masashi Yagi, Kentaro Wada, Shingo Oohira, Shoki Inui, Yusuke Anetai, Iori Sumida, Masayoshi Miyazaki, Kazuhiko Ogawa, Teruki Teshima,
    • Organizer
      American Society for Radiation Oncology
    • Related Report
      2017 Research-status Report
    • Int'l Joint Research
  • [Presentation] TCP・NTCPを用いたIII期非小細胞肺癌に対する 最適な線量分割の検討2017

    • Author(s)
      上田悦弘、鈴木修、八木雅史、大平新吾、五十野優、乾翔輝、和田健太郎、宮崎正義、隅田伊織、小川和彦、手島昭樹
    • Organizer
      日本放射線腫瘍学会
    • Related Report
      2017 Research-status Report

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Published: 2017-04-28   Modified: 2022-01-27  

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