The large-scale cohort study on life-style related risk factors for CKD
Project/Area Number |
17K15850
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Research Category |
Grant-in-Aid for Young Scientists (B)
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Allocation Type | Multi-year Fund |
Research Field |
Hygiene and public health
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Research Institution | Niigata University |
Principal Investigator |
Kabasawa Keiko 新潟大学, 医歯学総合研究科, 特任助教 (70529726)
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Project Period (FY) |
2018-02-28 – 2022-03-31
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Project Status |
Completed (Fiscal Year 2021)
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Budget Amount *help |
¥4,550,000 (Direct Cost: ¥3,500,000、Indirect Cost: ¥1,050,000)
Fiscal Year 2020: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Fiscal Year 2019: ¥390,000 (Direct Cost: ¥300,000、Indirect Cost: ¥90,000)
Fiscal Year 2018: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2017: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
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Keywords | 慢性腎臓病 / コホート研究 / 生活習慣 |
Outline of Final Research Achievements |
Using the framework of an ongoing large-scale prospective cohort study (the Uonuma cohort study, 40 years and older, N = 39,764), this study aimed to collect the case of chronic kidney disease (CKD) and identify its lifestyle-related risk factors. Among respondents to the 5-year follow-up survey (n = 30,495), 2.8% self-reported new onset of CKD during the 5-year follow-up period. Using the baseline data, we found the associations of dietary acid load and sodium-to-potassium ratio with albuminuria, and muscle strength (grip strength) with kidney function.
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Academic Significance and Societal Importance of the Research Achievements |
CKDは糖尿病や高血圧などの生活習慣病が主なリスク因子であり、進行すると末期腎不全だけでなく、心血管病の発症リスクを高める。本研究では、大規模な一般地域住民コホートを用い、5年後追跡調査を完了するとともに、ベースライン調査からCKDの生活習慣関連因子を明らかにすることができた。本研究から発信されるエビデンスは日本人のCKD一次予防戦略のための基礎資料となる。
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Report
(5 results)
Research Products
(8 results)
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[Journal Article] Study Design and Baseline Profiles of Participants in the Uonuma CKD Cohort Study in Niigata, Japan2020
Author(s)
Kabasawa K, Tanaka J, Nakamura K, Ito Y, Yoshida K, Takachi R, Sawada N, Tsugane S, Narita I
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Journal Title
Journal of Epidemiology
Volume: 30
Issue: 4
Pages: 170-176
DOI
NAID
ISSN
0917-5040, 1349-9092
Year and Date
2020-04-05
Related Report
Peer Reviewed / Open Access
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