Diagnostic biomarkers for Acute encephalopathy with biphasic seizures and reduced diffusion using integrated cerebral function analysis
| Project/Area Number |
17K16271
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Multi-year Fund |
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| Research Field |
Pediatrics
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| Research Institution | Kyushu University |
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Principal Investigator |
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| Project Period (FY) |
2017-04-01 – 2021-03-31
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| Project Status |
Completed (Fiscal Year 2020)
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| Budget Amount *help |
¥4,160,000 (Direct Cost: ¥3,200,000、Indirect Cost: ¥960,000)
Fiscal Year 2019: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2018: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2017: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
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| Keywords | 小児急性脳症 / 急性期脳波 / NIRS / 症候性てんかん / AESD / けいれん重積 / 脳波 / けいれん重積型脳症 / 脳波周波数解析 / 神経科学 |
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| Outline of Final Research Achievements |
We reported acute through convalescent phase factors to predict the development and outcomes of post-encephalopathic epilepsy with acute encephalopathy with biphasic seizures and late reduced diffusion.
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| Academic Significance and Societal Importance of the Research Achievements |
急性脳症の国内発症数は年間推定400～700名、この中でAESDは最も頻度が高く、年間100～200人であり、小児神経学領域で最重要課題である。また本疾患については本邦からの報告がほとんどである。本研究ではAESD病変のMRI定量的解析を行い、急性期病変が広く萎縮が強い症例ほど遠隔期にてんかん発症しやすい傾向があることを明らかにした。
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Report
(5 results)
Research Products
(4 results)
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[Journal Article] Predictive indicators for the development of epilepsy after acute encephalopathy with biphasic seizures and late reduced diffusion2018
Author(s)
Yuko Ichimiya, Noriyuki Kaku, Masafumi Sanefuji, Michiko Torio, Soichi Mizuguchi, Yoshitomo Motomura, Mamoru Muraoka, Sooyoung Lee, Haruhisa Baba, Yuri Sonoda, Yoshito Ishizaki, Momoko Sasazuki, Yasunari Sakai, Yoshihiko Maehara, Shouichi Ohga
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Journal Title
Epilepsy Research
Volume: 143
Pages: 70-74
Related Report
Peer Reviewed / Open Access
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