| Budget Amount *help |
¥3,900,000 (Direct Cost: ¥3,000,000、Indirect Cost: ¥900,000)
Fiscal Year 2019: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2018: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2017: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
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| Outline of Final Research Achievements |
To explore neonatal circadian rhythms, we observed and analyzed urinary cortisol and urinary 6-sulfatoxymelatonin in newborns over time. In addition, we aimed to evaluate the accuracy of sleep-wake detection by actigraphy. No rhythm was observed in urinary 6-sulfatoxymelatonin. Urinary cortisol in preterm infants who were born more than 30 days later showed a bimodal rhythm rising in the morning and evening. There was no apparent relationship between the two parameters. Actigraphy was able to determine sleep-wake with an accuracy of about 87% when the activity score was 124.
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