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Investigation of cut-off value for pediatric obesity index based on evidence

Research Project

Project/Area Number 17K16291
Research Category

Grant-in-Aid for Young Scientists (B)

Allocation TypeMulti-year Fund
Research Field Pediatrics
Research InstitutionNational Center for Child Health and Development

Principal Investigator

Okubo Yusuke  国立研究開発法人国立成育医療研究センター, 社会医学研究部, リサーチアソシエイト (10795991)

Project Period (FY) 2017-04-01 – 2020-03-31
Project Status Completed (Fiscal Year 2019)
Budget Amount *help
¥3,900,000 (Direct Cost: ¥3,000,000、Indirect Cost: ¥900,000)
Fiscal Year 2018: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
Fiscal Year 2017: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
Keywords小児肥満 / 疫学 / 感染症 / 急性疾患 / BPA / カットオフ / 臨床 / 入院患者 / DPCデータベース / Kids Inpatient Database
Outline of Final Research Achievements

We investigated the impacts of pediatric obesity on acute infectious illness among children hospitalized with asthma, acute lower respiratory infection, urinary tract infection, and influenza pneumonia. We observed pediatric obesity had effects on elevated risk of illness severity, increased healthcare costs and duration of hospitalization, and elevated rates of repeated admission.
For this study, we utilized obesity index referred to WHO definition, but it predicted these risk factors well.

Academic Significance and Societal Importance of the Research Achievements

小児の肥満において、乳幼児期から急性疾患に影響を示している。これは、乳幼児期においても、肥満は公衆衛生上の問題となりえ、さらに予防することで、感染症の重症化や再入院率を下げる等の効果が示唆される内容であった。
また、日本は肥満の指標として、ローレル指数、カウプ指数、肥満度などを使用してきたが、WHOの推奨するweight-for-length/heightを用いた場合、重症化の予測としては優れていた。

Report

(4 results)
  • 2019 Annual Research Report   Final Research Report ( PDF )
  • 2018 Research-status Report
  • 2017 Research-status Report
  • Research Products

    (7 results)

All 2019 2018 2017 Other

All Int'l Joint Research (1 results) Journal Article (6 results) (of which Int'l Joint Research: 5 results,  Peer Reviewed: 6 results)

  • [Int'l Joint Research] Harvard School of Public Health/UCLA Fielding School of Public Health(米国)

    • Related Report
      2017 Research-status Report
  • [Journal Article] Serial cross‐sectional study for the association between urinary bisphenol A and paediatric obesity: Recent updates using NHANES 2003‐20142019

    • Author(s)
      Okubo Yusuke、Handa Atsuhiko、Belin Thomas
    • Journal Title

      Pediatric Obesity

      Volume: 14 Issue: 12

    • DOI

      10.1111/ijpo.12566

    • Related Report
      2019 Annual Research Report
    • Peer Reviewed / Int'l Joint Research
  • [Journal Article] Dose-dependent relationships between weight status and clinical outcomes among infants hospitalized with respiratory syncytial virus infections2018

    • Author(s)
      Okubo Yusuke、Morisaki Naho、Michihata Nobuaki、Matsui Hiroki、Fushimi Kiyohide、Yasunaga Hideo
    • Journal Title

      Pediatric Pulmonology

      Volume: 53 Issue: 4 Pages: 461-466

    • DOI

      10.1002/ppul.23949

    • Related Report
      2018 Research-status Report 2017 Research-status Report
    • Peer Reviewed
  • [Journal Article] The impact of obesity on pediatric inpatients with urinary tract infections in the United States.2017

    • Author(s)
      Yusuke Okubo
    • Journal Title

      J Pediatr Urol.

      Volume: 13 Issue: 5 Pages: 455-455

    • DOI

      10.1016/j.jpurol.2017.03.038

    • Related Report
      2017 Research-status Report
    • Peer Reviewed / Int'l Joint Research
  • [Journal Article] The impact of pediatric obesity on hospitalized children with lower respiratory tract infections in the United States2017

    • Author(s)
      Okubo Yusuke、Nochioka Kotaro、Testa Marcia A.
    • Journal Title

      The Clinical Respiratory Journal

      Volume: 12 Issue: 4 Pages: 1479-1484

    • DOI

      10.1111/crj.12694

    • Related Report
      2017 Research-status Report
    • Peer Reviewed / Int'l Joint Research
  • [Journal Article] Impact of pediatric obesity on acute asthma exacerbation in Japan2017

    • Author(s)
      Okubo Yusuke、Michihata Nobuaki、Yoshida Koichi、Morisaki Naho、Matsui Hiroki、Fushimi Kiyohide、Yasunaga Hideo
    • Journal Title

      Pediatric Allergy and Immunology

      Volume: 28 Issue: 8 Pages: 763-767

    • DOI

      10.1111/pai.12801

    • Related Report
      2017 Research-status Report
    • Peer Reviewed / Int'l Joint Research
  • [Journal Article] Dose-response relationship between weight status and clinical outcomes in pediatric influenza-related respiratory infections2017

    • Author(s)
      Okubo Yusuke、Michihata Nobuaki、Uda Kazuhiro、Morisaki Naho、Miyairi Isao、Matsui Hiroki、Fushimi Kiyohide、Yasunaga Hideo
    • Journal Title

      Pediatric Pulmonology

      Volume: 53 Issue: 2 Pages: 218-223

    • DOI

      10.1002/ppul.23927

    • Related Report
      2017 Research-status Report
    • Peer Reviewed / Int'l Joint Research

URL: 

Published: 2017-04-28   Modified: 2022-02-21  

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