| Budget Amount *help |
¥4,160,000 (Direct Cost: ¥3,200,000、Indirect Cost: ¥960,000)
Fiscal Year 2019: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2018: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2017: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
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| Outline of Final Research Achievements |
Abnormalities in autophagy have been shown to be involved in the pathogenesis of a variety of diseases. We have found that Vsp34 (a class III PI3-kinase)-deficient mouse epidermis developed lesions similar to those in psoriasis vulgaris. In psoriasis, the epidermis is abnormally thickened, suggesting a relationship with stem cells. As part of our stem cell research,we have also found that the transcription factor Sox13 could serve as a novel marker for hair follicle stem cells.
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