| Budget Amount *help |
¥4,160,000 (Direct Cost: ¥3,200,000、Indirect Cost: ¥960,000)
Fiscal Year 2020: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2019: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2018: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2017: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
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| Outline of Final Research Achievements |
A cell sheets were prepared from cardiomyocytes differentiated from human iPS cells and transplanted on the subcutaneous tissues of animals. And we successfully cultured human iPS myocardial tissue in vivo. First, in order to eliminate the effects of anesthesia and surgical invasion on myocardial tissue, we developed a system that can continuously measure the surface potential of human iPS myocardial tissue even when the animal is awake. Electrical activities of human iPS myocardial tissue were recorded over time with this system. Results were that the surface potential waveform of myocardial tissue became stable as the culture period became longer.
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