Investigation of mechanism for radiation induced brain tumor stem cell migration
| Project/Area Number |
17K16668
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Multi-year Fund |
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| Research Field |
Neurosurgery
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| Research Institution | National Institute of Advanced Industrial Science and Technology (2019)
University of Tsukuba (2017-2018) |
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Principal Investigator |
Sun Lue 国立研究開発法人産業技術総合研究所, 生命工学領域, 研究員 (40757704)
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| Project Period (FY) |
2017-04-01 – 2020-03-31
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| Project Status |
Completed (Fiscal Year 2019)
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| Budget Amount *help |
¥4,030,000 (Direct Cost: ¥3,100,000、Indirect Cost: ¥930,000)
Fiscal Year 2019: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2018: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2017: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
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| Keywords | 放射線治療 / 脳腫瘍幹細胞 / 転移 / 浸潤 / 放射線 / 脳腫瘍 / がん幹細胞 / 代謝 / ミトコンドリア / レドックス |
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| Outline of Final Research Achievements |
We investigated mechanism for radiation induced brain tumor stem cell migration using we established brain tumor stem like cell line.
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| Academic Significance and Societal Importance of the Research Achievements |
本研究は、放射線照射後の細胞の遊走浸潤という独自の視点から、脳腫瘍幹細胞様細胞の新たな放射線抵抗性メカニズムを解明しようと試みるものである。研究の成果は、遊走阻止効果を期待した薬剤併用療法に関して、理論的根拠を導くことができる。
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Report
(4 results)
Research Products
(7 results)
