| Budget Amount *help |
¥4,160,000 (Direct Cost: ¥3,200,000、Indirect Cost: ¥960,000)
Fiscal Year 2019: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2018: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2017: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
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| Outline of Final Research Achievements |
During emergency laparotomy in human neonates, we were able to investigate the differences in gene expression between diseases with strong inflammation (necrotizing enteritis) and those without strong inflammation (such as localized bowel perforation). In terms of gene expression, we looked at about 10,000 cells per case in each of the intestinal tracts, so we can assess what cells specifically were showing abnormal responses. To date, there have been no reports of such gene expression analysis on a cell-by-cell basis. Further research could lead to the development of novel treatments and prevention of diseases such as necrotizing enteritis.
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