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Assessment system of swallowing function in Parkinson's disease

Research Project

Project/Area Number 17K17167
Research Category

Grant-in-Aid for Young Scientists (B)

Allocation TypeMulti-year Fund
Research Field Prosthodontics/ Dental materials science and
Research InstitutionOsaka University

Principal Investigator

Minagi Yoshitomo  大阪大学, 歯学研究科, 招へい教員 (30755351)

Project Period (FY) 2017-04-01 – 2020-03-31
Project Status Completed (Fiscal Year 2019)
Budget Amount *help
¥4,160,000 (Direct Cost: ¥3,200,000、Indirect Cost: ¥960,000)
Fiscal Year 2018: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
Fiscal Year 2017: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
Keywords摂食嚥下リハビリテーション / 舌圧 / パーキンソン病 / 舌機能 / 顎口腔機能 / 摂食嚥下障害 / 歯学 / リハビリテーション / 脳神経疾患
Outline of Final Research Achievements

The purpose of this project is to make research the specificity of Parkinson disease(PD) under swallowing by measuring tongue pressure which generates when tongue comes in contact with hard palate.
Our results indicated that the magnitude of tongue pressure decreased in PD patients with or without dysphagia. Moreover the decreased tongue pressure made bad influence on oral and pharyngeal stage of swallowing. These results indicate the possibility that measuring tongue pressure becomes an new diagnosis tool for dysphagic PD patients and contributes on making clinical strategies for dysphagia.

Academic Significance and Societal Importance of the Research Achievements

申請者は,嚥下時の舌と口蓋の接触圧,すなわち「舌圧」に着目し,パーキンソン病における口腔期から咽頭期までの一連の嚥下動態についての疾患特異性を明らかにすることを目的として研究を進めてきた.
計測結果より,パーキンソン病患者においては嚥下障害の有無にかかわらず嚥下時舌圧が低下することがわかった.また,嚥下時舌圧の低下が口腔期だけでなく咽頭期にも影響を及ぼす可能性が示唆された.これらのことは舌圧計測がパーキンソン病嚥下障害患者の新たな診断ツールとなり,パーキンソン病患者の嚥下障害の診断・治療に貢献する可能性を示したといえる.

Report

(4 results)
  • 2019 Annual Research Report   Final Research Report ( PDF )
  • 2018 Research-status Report
  • 2017 Research-status Report
  • Research Products

    (9 results)

All 2020 2019 2018 2017

All Journal Article (5 results) (of which Peer Reviewed: 4 results,  Open Access: 3 results) Presentation (4 results) (of which Invited: 2 results)

  • [Journal Article] Coordination of tongue pressure production, hyoid movement, and suprahyoid muscle activity during squeezing of gels2020

    • Author(s)
      Murakami Kazuhiro、Hori Kazuhiro、Minagi Yoshitomo、Uehara Fumiko、Salazar Simonne E.、Ishihara Sayaka、Nakauma Makoto、Funami Takahiro、Ikebe Kazunori、Maeda Yoshinobu、Ono Takahiro
    • Journal Title

      Archives of Oral Biology

      Volume: 111 Pages: 104631-104631

    • DOI

      10.1016/j.archoralbio.2019.104631

    • Related Report
      2019 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Evaluation of hyoid movement during swallowing using a bend sensor2019

    • Author(s)
      Murakami Kazuhiro、Minagi Yoshitomo、Hori Kazuhiro、Uehara Fumiko、Salazar Simonne E.、Inoue Makoto、Maeda Yoshinobu、Ikebe Kazunori、Ono Takahiro
    • Journal Title

      Journal of Oral Rehabilitation

      Volume: 47 Issue: 3 Pages: 339-345

    • DOI

      10.1111/joor.12906

    • Related Report
      2019 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Relationships between dysphagia and tongue pressure during swallowing in Parkinson's disease patients.2018

    • Author(s)
      Minagi Y, Ono T, Hori K, Fujiwara S, Tokuda Y, Murakami K, Maeda Y, Sakoda S, Yokoe M, Mihara M, Mochizuki H.
    • Journal Title

      Journal of oral rehabilitation

      Volume: in press Issue: 6 Pages: 459-466

    • DOI

      10.1111/joor.12626

    • Related Report
      2018 Research-status Report 2017 Research-status Report
    • Peer Reviewed / Open Access
  • [Journal Article] 摂食嚥下リハビリテーションに おける嚥下時舌圧測定の有用性2017

    • Author(s)
      小野高裕 ,堀 一浩, 藤原茂弘, 皆木祥伴,村上和裕
    • Journal Title

      リハビリテーション医学

      Volume: 54 Pages: 666-671

    • NAID

      130006192294

    • Related Report
      2017 Research-status Report
    • Open Access
  • [Journal Article] The biomechanical coordination during oropharyngeal swallowing: an evaluation with a non-invasive sensing system.2017

    • Author(s)
      Li Q, Minagi Y, Ono T, Chen Y, Hori K, Fujiwara S, Maeda Y.
    • Journal Title

      Scientific reports

      Volume: 7 Issue: 1 Pages: 15243-6

    • DOI

      10.1038/s41598-017-15243-6

    • Related Report
      2017 Research-status Report
    • Peer Reviewed / Open Access
  • [Presentation] 舌の硬さとスクイージング機能の関係2019

    • Author(s)
      笠川尚彦,皆木祥伴,村上和裕,堀一浩,小野高裕,池邉一典
    • Organizer
      日本顎口腔機能学会第62回学術大会
    • Related Report
      2019 Annual Research Report
  • [Presentation] 嚥下時舌圧測定を用いた口腔期嚥下障害の評価と舌接触補助床(PAP)製作における勘所2018

    • Author(s)
      皆木祥伴
    • Organizer
      摂食嚥下リハビリテーション学会
    • Related Report
      2018 Research-status Report
    • Invited
  • [Presentation] ゼリーの舌押し潰し嚥下時における舌圧発現と舌骨移動2017

    • Author(s)
      村上和裕,堀一浩,皆木祥伴,藤原茂弘,徳田佳嗣, Simonne E. Salazar,上原文子,井上誠,小野高裕,前田芳信
    • Organizer
      日本顎口腔機能学会
    • Related Report
      2017 Research-status Report
  • [Presentation] 臨床に活きる「義歯」のお話 ~発話へのアプローチを中心に~2017

    • Author(s)
      皆木祥伴
    • Organizer
      大阪府言語聴覚士会 構音障害分科会
    • Related Report
      2017 Research-status Report
    • Invited

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Published: 2017-04-28   Modified: 2021-02-19  

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