Development of artificial enamel with controllable mechanical properties

• Project/Area Number: 17K17185
• Research Category: Grant-in-Aid for Young Scientists (B)
• Allocation Type: Multi-year Fund
• Research Field: Prosthodontics/ Dental materials science and
• Research Institution: Kyushu Dental College
• Principal Investigator: Ikeda Hiroshi 九州歯科大学, 歯学部, 助教 (80621599)
• Project Period (FY): 2017-04-01 – 2020-03-31
• Project Status: Completed (Fiscal Year 2019)
• Budget Amount: ¥4,160,000 (Direct Cost: ¥3,200,000、Indirect Cost: ¥960,000); Fiscal Year 2019: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000); Fiscal Year 2018: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000); Fiscal Year 2017: ¥2,340,000 (Direct Cost: ¥1,800,000、Indirect Cost: ¥540,000)
• Keywords: コンポジット / エナメル質 / 歯冠修復物 / 複合材料 / 生体材料

Outline of Final Research Achievements

Mechanical properties such as hardness and elastic modulus are important for a crown restorative material. However, there is no practical materials with mechanical compatibility to human enamel. Purpose of this study is to fabricate organic-inorganic composite mimicking mechanical properties of human enamel. An SiO2-PMMA composite was synthesised via polymer infiltration process. The resultant composite has nano-dual network structure composed of SiO2 skeleton and infiltrated PMMA phase. Mechanical properties of this composite was close to those of human enamel.

Academic Significance and Societal Importance of the Research Achievements

人工エナメル質は、数センチのブロック状の塊として得られるため、CAD/CAMシステムなどの機械加工によって歯冠形状に成型・加工できる。実用に耐えうる強度と審美性が得られれば、天然エナメル質と同等の機械的性質と審美性を併せもつ歯冠修復物が実現できる。

Research Products

• [Journal Article] Correlation between microstructure of CAD/CAM composites and the silanization effect on adhesive bonding (2020)
  • Author(s): Yano Haruka Takesue、Ikeda Hiroshi、Nagamatsu Yuki、Masaki Chihiro、Hosokawa Ryuji、Shimizu Hiroshi
  • Journal Title: Journal of the Mechanical Behavior of Biomedical Materials Volume: 101 Pages: 103441-103441
  • DOI: 10.1016/j.jmbbm.2019.103441
  • Peer Reviewed / Open Access
• [Journal Article] Preparation of silica?poly(methyl methacrylate) composite with a nanoscale dual-network structure and hardness comparable to human enamel (2019)
  • Author(s): Ikeda Hiroshi、Nagamatsu Yuki、Shimizu Hiroshi
  • Journal Title: Dental Materials Volume: 35 Issue: 6 Pages: 893-899
  • DOI: 10.1016/j.dental.2019.03.006
  • Peer Reviewed
• [Journal Article] Data on changes in flexural strength and elastic modulus of dental CAD/CAM composites after deterioration tests (2019)
  • Author(s): Ikeda Hiroshi、Nagamatsu Yuki、Shimizu Hiroshi
  • Journal Title: Data in Brief Volume: 24 Pages: 103889-103889
  • DOI: 10.1016/j.dib.2019.103889
  • Peer Reviewed / Open Access
• [Journal Article] CAD/CAM用コンポジットレジンの微細構造と機械的性質 (2017)
  • Author(s): 池田弘, 永松有紀, 清水博史
  • Journal Title: 九州歯科学会雑誌 Volume: 71 Pages: 52-59
  • Peer Reviewed
• [Presentation] Preparation and characterization of silica based nanocomposite with compatible hardness to human enamel (2019)
  • Author(s): Ikeda H, Nagamatsu Y, Shimizu H
  • Organizer: 7th Asian Pacific International Conference
  • Int'l Joint Research
• [Presentation] Preparation of SiO2-PMMA composite with a nanoscale dual-network structure (2019)
  • Author(s): Ikeda H, Nagamatsu Y, Shimizu H
  • Organizer: 97th General Session & Exhibition of the IADR
  • Int'l Joint Research
• [Presentation] Preparation and Characterization of polymer-infiltrated-ceramic with hardness comparable to human-enamel. (2019)
  • Author(s): Ikeda H, Nagamatsu Y, Shimizu H
  • Organizer: 4th meeting of the IADR Asia Pacific Region 2019
  • Int'l Joint Research
• [Presentation] 孤立シラノール基の制御とナノ共連続構造体の曲げ強さ (2019)
  • Author(s): 池田弘，永松有紀，清水博史
  • Organizer: 第73回日本歯科理工学会
• [Presentation] CAD/CAM用コンポジットレジンの機械的性質と接着特性 (2019)
  • Author(s): 池田弘，永松有紀，清水博史
  • Organizer: 日本歯科理工学会九州地方会夏期セミナー
• [Presentation] Microstructure and Mechanical properties of CAD/CAM composites (2019)
  • Author(s): Ikeda H
  • Organizer: 7th Biennial Joint Congress of KAP-CPS-JPS
  • Int'l Joint Research / Invited
• [Presentation] SiO2-PMMA ナノ共連続構造体の機械的性質 (2018)
  • Author(s): 池田弘, 永松有紀, 清水博史
  • Organizer: 第71回日本歯科理工学会春期学術講演会
• [Presentation] ナノ共連続構造をもつ歯冠修復用複合材料の開発 (2018)
  • Author(s): 池田弘, 永松有紀, 清水博史
  • Organizer: 平成30年度日本歯科理工学会九州地方会夏期セミナー
• [Presentation] 有機-無機ナノ共連続構造体の作製工程へのシラン処理の導入とその効果 (2018)
  • Author(s): 池田弘, 永松有紀, 清水博史
  • Organizer: 第72回日本歯科理工学会春期学術講演会
• [Presentation] Polymer infiltrated SiO2-PMMA composite with compatible hardness to enamel (2018)
  • Author(s): Ikeda H, Nagamatsu Y, Shimizu H
  • Organizer: 2018 IADR/PER Genetral Session & Exhibition
  • Int'l Joint Research
• [Presentation] CAD/CAM用コンポジットレジンの現状と将来展望 (2018)
  • Author(s): 池田 弘
  • Organizer: 第77回九州歯科学会
  • Invited
• [Presentation] 新規な共連続ナノ構造をもつ複合材料の開発 (2018)
  • Author(s): 池田 弘，永松有紀，清水博史
  • Organizer: 日本歯科理工学会九州地方会
• [Presentation] ヒトエナメル質と同等の硬さを持つCAD/CAM用新素材の開発 (2018)
  • Author(s): 池田 弘，永松有紀，清水博史
  • Organizer: 日本補綴歯科学会九州支部学術大会
• [Presentation] ヒトエナメル質と同等の硬さを持つ歯冠修復複合材料の開発 (2018)
  • Author(s): 池田 弘，永松有紀，清水博史
  • Organizer: 第70回日本歯科理工学会
• [Presentation] 高接着性を目指した新規歯冠修復用複合材料の開発 (2018)
  • Author(s): 池田 弘，永松有紀，川口智弘，髙橋 裕，清水博史
  • Organizer: 第36回日本接着歯学会