Physical activity and the risk of stroke recurrence in patients with a history of minor ischemic stroke in Japan

• Project/Area Number: 17K17442
• Research Category: Grant-in-Aid for Young Scientists (B)
• Allocation Type: Multi-year Fund
• Research Field: Clinical nursing
• Research Institution: Fukuoka jogakuin Nursing College (2020-2023); Kyushu University (2017-2019)
• Principal Investigator: USHIO Miyuki 福岡女学院看護大学, 看護学部, 講師 (40622113)
• Project Period (FY): 2017-04-01 – 2024-03-31
• Project Status: Completed (Fiscal Year 2023)
• Budget Amount: ¥4,290,000 (Direct Cost: ¥3,300,000、Indirect Cost: ¥990,000); Fiscal Year 2020: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000); Fiscal Year 2019: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000); Fiscal Year 2018: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000); Fiscal Year 2017: ¥2,340,000 (Direct Cost: ¥1,800,000、Indirect Cost: ¥540,000)
• Keywords: Stroke / Phyisical Activity / 脳梗塞 / 身体活動 / QOL / 身体活動量 / 活動調査票 / 軽症脳梗塞 / 再発予防 / 再発

Outline of Final Research Achievements

A total of 45 outpatients (mean age 67.1 ± 10.2 years) who had previously experienced a transient ischemic attack or a minor non-cardioembolic ischemic stroke at a single hospital in Japan. RIS occurred in 9 patients; they had significantly higher visceral fat level (p = 0.007) and %body fat (p = 0.007) values and lower MVPA (p = 0.011) values than patients without recurrence. A multivariate analysis of these factors indicated that age, visceral fat level and MVPA were significant independent predictors of RIS.

Academic Significance and Societal Importance of the Research Achievements

TIAおよび非心原性の軽症脳梗塞の再発を経験した患者は中強度以上の身体活動量が低く、内臓脂肪レベルが高かった。低い中強度以上の身体活動量と内臓脂肪型肥満の保有は脳梗塞再発リスクの指標となる可能性が指摘された。このことは脳梗塞再発のリスク評価においては、BMIや体脂肪よりもVFLの精度が高い可能性を示している。BI法は侵襲がない簡便な測定用具であり、臨床の様々な診療科で使用されている。今後は軽症脳梗塞患者の再発予防においても、BI法の有用性を検討していく必要がある。

Research Products

• [Journal Article] Moderate-to-vigorous physical activity and the risk of stroke recurrence in patients with a history of minor ischemic stroke in Japan: a retrospective analysis (2018)
  • Author(s): Miyuki Ushio, Maki Kanaoka, Yumiko Kinoshita, Satoko Maeno, Kimie Fujita
  • Journal Title: Topics in Stroke Rehabilitation Volume: 12 Issue: 8 Pages: 591-598
  • DOI: 10.1080/10749357.2018.1507309
  • Peer Reviewed / Open Access