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Life course research on maxillofacial morphology from fetal period to adulthood

Research Project

Project/Area Number 17K17697
Research Category

Grant-in-Aid for Young Scientists (B)

Allocation TypeMulti-year Fund
Research Field Orthodontics/Pediatric dentistry
Childhood science (childhood environment science)
Research InstitutionTokyo Medical and Dental University

Principal Investigator

Yasuda Yuko  東京医科歯科大学, 大学院医歯学総合研究科, 非常勤講師 (20707476)

Project Period (FY) 2017-04-01 – 2022-03-31
Project Status Completed (Fiscal Year 2021)
Budget Amount *help
¥4,290,000 (Direct Cost: ¥3,300,000、Indirect Cost: ¥990,000)
Fiscal Year 2019: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000)
Fiscal Year 2018: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2017: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
Keywords不正咬合 / 出生コホート / 喫煙 / モンゴロイド / 出生コホート研究 / 顎顔面形態 / ライフコースアプローチ / 口腔関連QoL / 顎関節症
Outline of Final Research Achievements

To clarify the effects of social and environmental factors during pregnancy and childhood on the onset of malocclusion and the influence of malocclusion on physical and mental health, we conducted a survey of all students (age, 12-15 years) enrolled in every junior high school (schools N = 5) in Koshu City. Koshu City is the field study area for Project Koshu, an ongoing prospective birth cohort study.
As a result, a longitudinal population-based study revealed an association between maternal smoking habits and the development of permanent tooth defects in their children. These results provide fundamental data for elucidating the mechanisms by which maternal smoking influences permanent tooth loss in children.

Academic Significance and Societal Importance of the Research Achievements

本研究にて明らかとなった不正咬合の発症要因、および不正咬合が健康状態に与える影響は、今後の不正咬合の予防・治療の政策を立案する上で重要な論理的基盤となり、結果として子どもの健康状態を改善することが可能となる。さらに本研究は自治体が主体で行っているため、学校や社会への還元が行いやすい環境にある。よって、不正咬合の予防政策の立案及び実施のモデルとなる可能性が期待できる。

Report

(6 results)
  • 2021 Annual Research Report   Final Research Report ( PDF )
  • 2020 Research-status Report
  • 2019 Research-status Report
  • 2018 Research-status Report
  • 2017 Research-status Report
  • Research Products

    (27 results)

All 2021 2020 2019 2018 2017

All Journal Article (6 results) (of which Int'l Joint Research: 3 results,  Peer Reviewed: 6 results,  Open Access: 5 results,  Acknowledgement Compliant: 1 results) Presentation (21 results) (of which Int'l Joint Research: 8 results)

  • [Journal Article] Association Between Malocclusion and Academic Performance Among Mongolian Adolescents2021

    • Author(s)
      Badrakhkhuu Nomin、Matsuyama Yusuke、Araki Miyu Yoshizawa、Yasuda Yuko Unnai、Ogawa Takuya、Tumurkhuu Tsasan、Ganburged Ganjargal、Bazar Amarsaikhan、Fujiwara Takeo、Moriyama Keiji
    • Journal Title

      Frontiers in Dental Medicine

      Volume: 1 Pages: 1-7

    • DOI

      10.3389/fdmed.2020.623768

    • Related Report
      2021 Annual Research Report 2020 Research-status Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Association between Smoking during Pregnancy and Short Root Anomaly in Offspring2021

    • Author(s)
      Sagawa Yuki、Ogawa Takuya、Matsuyama Yusuke、Nakagawa Kang Junka、Yoshizawa Araki Miyu、Unnai Yasuda Yuko、Tumurkhuu Tsasan、Ganburged Ganjargal、Bazar Amarsaikhan、Tanaka Toshihiro、Fujiwara Takeo、Moriyama Keiji
    • Journal Title

      International Journal of Environmental Research and Public Health

      Volume: 18 Issue: 21 Pages: 11662-11662

    • DOI

      10.3390/ijerph182111662

    • Related Report
      2021 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Association between Maternal Smoking during Pregnancy and Missing Teeth in Adolescents2019

    • Author(s)
      Nakagawa Kang Junka、Unnai Yasuda Yuko、Ogawa Takuya、Sato Miri、Yamagata Zentaro、Fujiwara Takeo、Moriyama Keiji
    • Journal Title

      International Journal of Environmental Research and Public Health

      Volume: 16 Issue: 22 Pages: 4536-4536

    • DOI

      10.3390/ijerph16224536

    • Related Report
      2019 Research-status Report
    • Peer Reviewed / Open Access
  • [Journal Article] Examination of craniofacial morphology in Japanese patients with congenitally missing teeth: a cross-sectional study2018

    • Author(s)
      Takahashi Yuki、Higashihori Norihisa、Yasuda Yuko、Takada Jun-ichi、Moriyama Keiji
    • Journal Title

      Progress in Orthodontics

      Volume: 19 Issue: 1 Pages: 38-38

    • DOI

      10.1186/s40510-018-0238-9

    • Related Report
      2018 Research-status Report
    • Peer Reviewed / Open Access
  • [Journal Article] Associations between Malocclusion and Oral Health-Related Quality of Life among Mongolian Adolescents2017

    • Author(s)
      Araki Miyu、Yasuda Yuko、Ogawa Takuya、Tumurkhuu Tsasan、Ganburged Ganjargal、Bazar Amarsaikhan、Fujiwara Takeo、Moriyama Keiji
    • Journal Title

      International Journal of Environmental Research and Public Health

      Volume: 14 Issue: 8 Pages: 902-902

    • DOI

      10.3390/ijerph14080902

    • Related Report
      2017 Research-status Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Trajectory of social inequalities in the treatment of dental caries among preschool children in Japan2017

    • Author(s)
      Aida, J., Matsuyama, Y., Tabuchi, T., Komazaki, Y., Tsuboya, T., Kato, T., Osaka, K., & Fujiwara, T.
    • Journal Title

      Journal of Community Dentistry & Oral Epidemiology

      Volume: 印刷中 Issue: 5 Pages: 1-6

    • DOI

      10.1111/cdoe.12304

    • Related Report
      2017 Research-status Report
    • Peer Reviewed / Acknowledgement Compliant
  • [Presentation] Association between maternal smoking and short root anomaly in offspring2021

    • Author(s)
      Sagawa Y, Ogawa T, Nakagawa Kang J, Yoshizawa Araki M, Unnai Yasuda Y, Tumurkhuu T, Ganburged G, Bazar A, Matsuyama Y, Fujiwara T, Moriyama K
    • Organizer
      The 99th General Session of the IADR, the 50th Meeting of the AADR and the 45th Meeting of the CADR
    • Related Report
      2021 Annual Research Report
    • Int'l Joint Research
  • [Presentation] 母親の妊娠期の喫煙習慣とその子どもの永久歯欠損の関連性について ~甲州市母子保健長期縦断調査より~2021

    • Author(s)
      姜順花、雲内裕子[保田]、小川卓也、森山啓司
    • Organizer
      第24回日本歯科医学会学術大会
    • Related Report
      2021 Annual Research Report
  • [Presentation] Okawara A, Yoshizawa(Araki) M, Unnai(Yasuda) Y, Ogawa T, Tumurkhuu T, Ganbrged G, Abzar A, Fujiwara T, Moriyama K2021

    • Author(s)
      Okawara A, Yoshizawa(Araki) M, Unnai(Yasuda) Y, Ogawa T, Tumurkhuu T, Ganbrged G, Abzar A, Fujiwara T, Moriyama K
    • Organizer
      The 80th Annual Meeting of the Japanese Orthodontic Society & The 5th International Congress
    • Related Report
      2021 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Association between posterior crossbite and physical ability between Mongolian adolescents2021

    • Author(s)
      Badrakhkhuu N, Matsuyama Y, Yoshizawa(Araki) Y, Unnai(Yasuda) Y, Ogawa T, Tumurkhuu T, Ganbrged G, Bazar A, Fujiwara T, Moriyama K
    • Organizer
      The 80th Annual Meeting of the Japanese Orthodontic Society & The 5th International Congress
    • Related Report
      2021 Annual Research Report
    • Int'l Joint Research
  • [Presentation] 妊娠中の母親の喫煙とShort root anomaly(SRA)の関連性について2021

    • Author(s)
      佐川夕季、小川卓也、姜順花、吉澤美祐、雲内(保田)裕子、森山啓司
    • Organizer
      第86回口腔病学会学術大会
    • Related Report
      2021 Annual Research Report
  • [Presentation] Association between Maternal Smoking during Pregnancy and Missing Teeth in Offspring2020

    • Author(s)
      Junka Nakagawa Kang, Yuko Unnai Yasuda, Takuya Ogawa, Miri Sato, Zentaro Yamagata, Takeo Fujiwara, and Keiji Moriyama
    • Organizer
      The 9th International Orthodontic Congress
    • Related Report
      2020 Research-status Report
    • Int'l Joint Research
  • [Presentation] 母親の妊娠期の喫煙習慣とその子どもの永久歯欠損の関連性について -甲州市母子保健長期縦断調 査より-2020

    • Author(s)
      姜 順花、保田 (雲内) 裕子、小川 卓也、山縣 然太朗、藤原 武男、森山 啓司
    • Organizer
      第79回東京矯正歯科学会学術大会
    • Related Report
      2020 Research-status Report
  • [Presentation] 片側性唇顎裂患者における上顎側切歯の先天欠如と顎裂形態との関連2019

    • Author(s)
      上園将慶、小川卓也、雲内(保田)裕子、荒木美祐、馬場優里、平塚泰三、森山啓司
    • Organizer
      第43回日本口蓋裂学会総会・学術集会
    • Related Report
      2019 Research-status Report
  • [Presentation] 成人期に至るまで咬合管理がなされず外科的矯正治療により咬合改善を図った片側性口唇口蓋裂の一症例2019

    • Author(s)
      荒木美祐、東堀紀尚、雲内(保田)裕子、有村恵、紙本裕幸、松本英和、小川卓也、森田圭一、依田哲也、森山啓司
    • Organizer
      第43回日本口蓋裂学会総会・学術集会
    • Related Report
      2019 Research-status Report
  • [Presentation] 当科における永久歯列期まで矯正歯科的管理がなされなかった口唇裂・口蓋裂患者の実態調査2019

    • Author(s)
      有村恵、荒木美祐、雲内(保田)裕子、東堀紀尚、小川卓也、森山啓司
    • Organizer
      第43回日本口蓋裂学会総会・学術集会
    • Related Report
      2019 Research-status Report
  • [Presentation] Association between Maternal Smoking During Pregnancy and Missing Teeth2019

    • Author(s)
      Kang Nakagawa J, Yasuda Y, Ogawa T, Sato M, Yamagata Z, Fujiwara T, Moriyama K
    • Organizer
      97th General Session & Exhibition of International Association for Dental Research
    • Related Report
      2019 Research-status Report
    • Int'l Joint Research
  • [Presentation] モンゴル人思春期児童における歯の異常に関する疫学調査2019

    • Author(s)
      有村恵、荒木美祐、雲内(保田)裕子、トムルホーツァサン、ガンブルゲドガンジャルガル、バザルアマルサイハン、小川卓也、森山啓司
    • Organizer
      第78回日本矯正歯科学会学術大会
    • Related Report
      2019 Research-status Report
  • [Presentation] 日本の思春期児童における不正咬合と口腔関連QoLとの関連について2018

    • Author(s)
      荒木美祐、保田裕子、小川卓也、姜順花、山縣然太朗、藤原武男、森山啓司
    • Organizer
      第77回日本矯正歯科学会学術大会
    • Related Report
      2018 Research-status Report
  • [Presentation] 母親の妊娠初期の喫煙習慣とその子どもの永久歯欠損の関連性について -甲州市母子保健長期縦断調査より-2018

    • Author(s)
      姜順花 保田裕子 小川卓也 佐藤美理 山縣然太朗 藤原武男 森山啓司
    • Organizer
      第29回日本疫学会学術総会
    • Related Report
      2018 Research-status Report
  • [Presentation] Association between malocclusion and temporomandibular disorders in 12-15-year-old Japanese adolescents: A population-based study.2018

    • Author(s)
      Yuko Yasuda, Takeo Fujiwara, Takuya Ogawa, Miyu Araki, Miri Sato, Zentaro Yamagata, Keiji Moriyama
    • Organizer
      The 11th Asian Pacific Orthodontic Conference.
    • Related Report
      2017 Research-status Report
    • Int'l Joint Research
  • [Presentation] 日本の思春期児童における不正咬合と口腔関連QoLとの関連について2018

    • Author(s)
      荒木美祐、保田裕子、小川卓也、姜順花、山縣然太朗、藤原武男、森山啓司
    • Organizer
      第76回日本矯正歯科学会大会
    • Related Report
      2017 Research-status Report
  • [Presentation] 日本の中学生における不正咬合と顎関節症との関連性について~甲州市母子保健縦断調査~2017

    • Author(s)
      駒﨑裕子、藤原武男、小川卓也、荒木美祐、佐藤美理、山縣然太朗、森山啓司
    • Organizer
      第27回日本疫学会学術総会
    • Related Report
      2017 Research-status Report
  • [Presentation] Association of malocclusion on oral health-related quality of life in Mongolian adolescents2017

    • Author(s)
      Miyu Araki, Yuko Yasuda, Takuya Ogawa, Tsasan Tumurkhuu, Ganjargal Ganburged, Amarsaikhan Bazar, Takeo Fujiwara, Keiji Moriyama
    • Organizer
      The 65th Annual Meeting of Japanese Association for Dental Research
    • Related Report
      2017 Research-status Report
    • Int'l Joint Research
  • [Presentation] モンゴル国の思春期児童における不正咬合と口腔関連QoLとの関連について2017

    • Author(s)
      6.荒木美祐、駒崎裕子、小川卓也、トムルホーツァサン、ガンブルゲドガンジャルガル、バザルアマルサイハン、川口陽子、藤原武男、森山啓司
    • Organizer
      第27回日本疫学会学術総会
    • Related Report
      2017 Research-status Report
  • [Presentation] 口唇裂・口蓋裂を伴う希少遺伝性疾患患者の矯正歯科治療に関する実態調査2017

    • Author(s)
      小川卓也、伴田みさと、上園将慶、駒崎裕子、森山啓司
    • Organizer
      第41回日本口蓋裂学会総会・学術大会
    • Related Report
      2017 Research-status Report
  • [Presentation] Postoperative changes of the maxilla after distraction osteogenesis in cleft palate patients Comparison between internal device and external device2017

    • Author(s)
      Yuko Komazaki, Takuya Ogawa, Yoshiyuki Baba, Keiji Moriyama
    • Organizer
      13th International Congress of Cleft Lip and Palate and Related Craniofacial Anomalies.
    • Related Report
      2017 Research-status Report
    • Int'l Joint Research

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Published: 2017-04-28   Modified: 2023-01-30  

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