| Budget Amount *help |
¥4,420,000 (Direct Cost: ¥3,400,000、Indirect Cost: ¥1,020,000)
Fiscal Year 2019: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2018: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2017: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
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| Outline of Final Research Achievements |
Herein, we developed a novel method to generate highly active species, o-quinodimethanes (OQMs) at room temperature. The reaction involves ring cleavage of the intermediate after a stable substrate was converted to a reactive molecule at room temperature.
The OQMs are so highly reactive that they act as “glue” to bind with partner molecules. Thus, we also developed a novel ligation reaction via OQMs at room temperature.
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