Budget Amount *help |
¥4,290,000 (Direct Cost: ¥3,300,000、Indirect Cost: ¥990,000)
Fiscal Year 2019: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2018: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2017: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
|
Outline of Final Research Achievements |
As a consequence of the analysis of acetaldehyde-induced DNA damage, we found novel regulatory factors of homologous recombination, SWSAP1 and FIGNL1. We also revealed FIGNL1 has an activity to prevent homologous recombination. In addition, the regulation by these proteins is essential for spermatogenesis and oogenesis in mice.
|