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Studies of the dynamics of cesium accumulated in fish with imaging mass spectrometry

Research Project

Project/Area Number 17K17861
Research Category

Grant-in-Aid for Young Scientists (B)

Allocation TypeMulti-year Fund
Research Field Aquatic life science
Risk sciences of radiation and chemicals
Research InstitutionOsaka University

Principal Investigator

Aoki Jun  大阪大学, 理学研究科, 助教 (90452424)

Project Period (FY) 2017-04-01 – 2020-03-31
Project Status Completed (Fiscal Year 2019)
Budget Amount *help
¥3,640,000 (Direct Cost: ¥2,800,000、Indirect Cost: ¥840,000)
Fiscal Year 2019: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2018: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2017: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
Keywordsイメージング質量分析 / 生物動態 / 動態分析 / 元素分布測定 / 環境分析 / 分析科学
Outline of Final Research Achievements

The purpose of this research is to clarify the dynamics of cesium accumlated in the body of fish by using imaging mass spectrometry. Because of the improvements of the our imaging mass spectrometer and the establishment of the sample processing method, the spatial resolution was reached to 1 μm and the measurement time was significantly reduced. With this device, the cesium distribution of the whole body of the fish was measured. As a result, cesium was detected in the digestive system after ingestion of cesium, and cesium was spread to the whole body in about 3 days. Furthermore, it was confirmed that the amount of cesium in the fish was reduced to half after 30 days.

Academic Significance and Societal Importance of the Research Achievements

本研究では、イメージング質量分析技術によって魚類におけるセシウムの蓄積動態を測定した。これにより魚の食べた食物中のセシウムが、消化器系から吸収されて全身に移行する様子が明らかとなった。さらにその後、30日をかけて生体内のセシウム濃度が低下する過程が確認された。この過程は、放射線セシウムに汚染された生物の扱いについて、重要な示唆を与えるものである。

Report

(4 results)
  • 2019 Annual Research Report   Final Research Report ( PDF )
  • 2018 Research-status Report
  • 2017 Research-status Report
  • Research Products

    (5 results)

All 2019 2018

All Presentation (5 results) (of which Int'l Joint Research: 4 results)

  • [Presentation] 投影型イメージング質量分析による高空間分解能かつ高速な分布計測2019

    • Author(s)
      青木順,豊田岐聡
    • Organizer
      67回質量分析総合討論会
    • Related Report
      2019 Annual Research Report
  • [Presentation] Development of High Spatial Resolution and High Speed Projection-type Imaging Mass Spectrometor2019

    • Author(s)
      Jun Aoki, Michisato Toyoda
    • Organizer
      The 67th ASMS Conference on Mass Spectrometry and Allied Topics
    • Related Report
      2019 Annual Research Report
    • Int'l Joint Research
  • [Presentation] High Spatial Resolution Observation of Metal Distribution in Fish by Projection-type Imaging Mass Spectrometer2019

    • Author(s)
      Jun Aoki, Michisato Toyoda
    • Organizer
      Metallomics 2019
    • Related Report
      2019 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Observation of Bioaccumulated Cesium Distribution in Marine Fish by using Imaging Mass Spectrometry2019

    • Author(s)
      Jun Aoki, Michisato Toyoda
    • Organizer
      Goldschmidt 2019
    • Related Report
      2019 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Development of High Spatial Resolution Stigmatic Imaging Mass Spectrometer2018

    • Author(s)
      Jun Aoki, Hisanao Hazama, Michisato Toyoda
    • Organizer
      Single Cell Europe 2018
    • Related Report
      2018 Research-status Report
    • Int'l Joint Research

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Published: 2017-04-28   Modified: 2021-02-19  

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