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Genetic basis of rapid divergence of Drosophila male external genitalia

Research Project

Project/Area Number 17K17985
Research Category

Grant-in-Aid for Young Scientists (B)

Allocation TypeMulti-year Fund
Research Field Developmental biology
Evolutionary biology
Research InstitutionTokyo Metropolitan University

Principal Investigator

Tanaka Kentaro  首都大学東京, 理学研究科, 特任研究員 (30774129)

Project Period (FY) 2017-04-01 – 2020-03-31
Project Status Completed (Fiscal Year 2019)
Budget Amount *help
¥4,290,000 (Direct Cost: ¥3,300,000、Indirect Cost: ¥990,000)
Fiscal Year 2019: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2018: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000)
Fiscal Year 2017: ¥2,470,000 (Direct Cost: ¥1,900,000、Indirect Cost: ¥570,000)
Keywords交尾器 / 形態進化 / キイロショウジョウバエ / ショウジョウバエ / 外部生殖器 / 雄外部生殖器 / 進化 / ゲノム / 発生・分化
Outline of Final Research Achievements

Genital morphology evolves rapidly, especially in males. Incompatible genital coupling between species is one of the mechanisms of isolation of species. Therefore, understanding genetic basis and behavioral outcomes of rapidly evolving genital morphology is an important issue in biology. In this study, I focused on rapid divergence of male genital structures among Drosophila melanogaster species subgroup as a model. Comparative gene expression analysis suggested that species-specific genital morphology is specified by changing expression of species-specific genes rather than common genes. Behavioral study also suggested that partial replacement (introgression) by a sibling species genome can induce perturbations in genital coupling mechanics, suggesting that genital compatibility can be susceptible to subtle genomic changes at the early stages of divergence.

Academic Significance and Societal Importance of the Research Achievements

交尾器形態は一般に進化速度の速い形態であることは広く認知されていることであったが、具体的にどのような遺伝子によって速く進化しているのかは不明であった。今回の研究結果からは、特定の遺伝子セットではなく、様々な発生関連遺伝子を利用することで交尾器形態は速い進化を遂げた可能性が見えてきた。また、種分化初期段階にみられるような、種間で交尾器形態が如実には違わない(少し異なる)場合でも交尾に不具合が生じることも明らかになった。種分化の初期段階においても交尾器は重要な役割を担っていたと考えられる。

Report

(4 results)
  • 2019 Annual Research Report   Final Research Report ( PDF )
  • 2018 Research-status Report
  • 2017 Research-status Report
  • Research Products

    (15 results)

All 2020 2019 2018 Other

All Int'l Joint Research (4 results) Journal Article (4 results) (of which Int'l Joint Research: 1 results,  Peer Reviewed: 4 results,  Open Access: 1 results) Presentation (7 results) (of which Int'l Joint Research: 1 results,  Invited: 1 results)

  • [Int'l Joint Research] Oxford Brookes University(英国)

    • Related Report
      2019 Annual Research Report
  • [Int'l Joint Research] University of Oklahoma(米国)

    • Related Report
      2019 Annual Research Report
  • [Int'l Joint Research] University of Oklahoma(米国)

    • Related Report
      2018 Research-status Report
  • [Int'l Joint Research] University of Oklahoma(米国)

    • Related Report
      2017 Research-status Report
  • [Journal Article] tartan underlies the evolution of Drosophila male genital morphology2019

    • Author(s)
      Hagen Joanna F. D.、Mendes Cludia C.、Blogg Amber、Payne Alexander、Tanaka Kentaro M.、Gaspar Pedro、Figueras Jimenez Javier、Kittelmann Maike、McGregor Alistair P.、Nunes Maria D. S.
    • Journal Title

      Proceedings of the National Academy of Sciences

      Volume: 116 Issue: 38 Pages: 19025-19030

    • DOI

      10.1073/pnas.1909829116

    • Related Report
      2019 Annual Research Report
    • Peer Reviewed / Int'l Joint Research
  • [Journal Article] Genetics of speciation: Advantages and limitations of using <i>Drosophila melanogaster</i> as a model organism2019

    • Author(s)
      髙橋 文、田中 健太郎
    • Journal Title

      JAPANESE JOURNAL OF ECOLOGY

      Volume: 69 Issue: 3 Pages: 183-190

    • DOI

      10.18960/seitai.69.3_183

    • NAID

      130007771841

    • ISSN
      0021-5007, 2424-127X
    • Related Report
      2019 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Mechanical incompatibility caused by modifications of multiple male genital structures using genomic introgression in Drosophila2018

    • Author(s)
      Tanaka KM, Kamimura Y and Takahashi A
    • Journal Title

      EVOLUTION

      Volume: 72(11) Issue: 11 Pages: 2406-2418

    • DOI

      10.1111/evo.13592

    • Related Report
      2018 Research-status Report
    • Peer Reviewed
  • [Journal Article] An innovative ovipositor for niche exploitation impacts genital coevolution between sexes in a fruit-damaging Drosophila2018

    • Author(s)
      Muto L, Kamimura Y, Tanaka KM and Takahashi A
    • Journal Title

      Proceedings of the Royal Society B

      Volume: 285 Issue: 1887 Pages: 20181635-20181635

    • DOI

      10.1098/rspb.2018.1635

    • Related Report
      2018 Research-status Report
    • Peer Reviewed
  • [Presentation] Deciphering cellular dynamics underlying rapid male genital diversification in Drosophila melanogaster species complex2020

    • Author(s)
      Tanaka KM, BucKman TC, Masly JP
    • Organizer
      Asia Pacific Drosophila Research Conference 5
    • Related Report
      2019 Annual Research Report
    • Int'l Joint Research
  • [Presentation] 種間変異がもたらすショウジョウバエ交尾器の接合時不適合性2019

    • Author(s)
      田中健太郎,上村佳孝,高橋文
    • Organizer
      第35回個体群生態学会
    • Related Report
      2019 Annual Research Report
  • [Presentation] Developmental and gene expression dynamics underlying rapid morphological evolution of Drosophila male genitalia2019

    • Author(s)
      Tanaka KM, BucKman TC, Masly JP
    • Organizer
      日本進化学会第21回大会
    • Related Report
      2019 Annual Research Report
  • [Presentation] Deciphering genital incompatibility by genomic introgression in Drosophila2019

    • Author(s)
      Tanaka KM
    • Organizer
      Mini-Symposium: Sexual Selection in Insects
    • Related Report
      2018 Research-status Report
    • Invited
  • [Presentation] How would you like to copulate? Rapid morphological evolution of male genitalia2018

    • Author(s)
      Tanaka KM, Kamimura Y and Takahashi A
    • Organizer
      第13回日本ショウジョウバエ研究会
    • Related Report
      2018 Research-status Report
  • [Presentation] Genetic basis underlying rapid divergence of male genital morphology between sibling species of Drosophila2018

    • Author(s)
      Tanaka KM, Kamimura Y, Takahashi A
    • Organizer
      The 46th NAITO CONFERECE: Mechanisms of Evolution and Biodiversity
    • Related Report
      2018 Research-status Report
  • [Presentation] 機械的隔離に関わる交尾器形態進化の遺伝的基盤2018

    • Author(s)
      田中健太郎,高橋文
    • Organizer
      日本進化学会第20回大会
    • Related Report
      2018 Research-status Report

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Published: 2017-04-28   Modified: 2022-02-21  

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