| Budget Amount *help |
¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2018: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Fiscal Year 2017: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
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| Outline of Final Research Achievements |
It has been reported that diabetes increases not only cardiovascular diseases, such as myocardial infarction and stroke, but also various cancers. Low-dose aspirin therapy has been conventionally used to prevent cardiovascular disease, but recently, attention has also been paid to the effect of aspirin on cancer chemoprevention, especially colorectal cancer.
In this study, we analyzed whether low-dose aspirin could reduce cancer incidence in patients with diabetes. We employed the JPAD study cohort, which include 2,536 Japanese patients with type 2 diabetes. During the median follow-up period of 12.3 years, 358 patients developed cancer. But low-dose aspirin therapy did not reduce cancer development. We plan to continue research and analysis using this cohort.
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