| Budget Amount *help |
¥4,290,000 (Direct Cost: ¥3,300,000、Indirect Cost: ¥990,000)
Fiscal Year 2019: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2018: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2017: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
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| Outline of Final Research Achievements |
The importance of MATE-type transporters as organic cation excretion transporters in the kidney and liver is widely recognized. On the other hand, functions other than organic cation excretion have been suggested, the aim of this study was to determine the function of MATE-type transporter as a testosterone transporter. Using primary cultured pig Leydig cells, we found that MATE-type transporter may be involved in testosterone secretion from Leydig cells and further suggested that human MATE1 may be involved in testosterone transport.
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