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Development of a radiation field with variable neutron energy spectrum

Research Project

Project/Area Number 17K18374
Research Category

Grant-in-Aid for Young Scientists (B)

Allocation TypeMulti-year Fund
Research Field Medical Physics and Radiological Technology
Nuclear engineering
Research InstitutionNational Institutes for Quantum and Radiological Science and Technology

Principal Investigator

Yonai Shunsuke  国立研究開発法人量子科学技術研究開発機構, 放射線医学総合研究所 物理工学部, グループリーダー(定常) (00415431)

Project Period (FY) 2017-04-01 – 2020-03-31
Project Status Completed (Fiscal Year 2019)
Budget Amount *help
¥4,420,000 (Direct Cost: ¥3,400,000、Indirect Cost: ¥1,020,000)
Fiscal Year 2019: ¥520,000 (Direct Cost: ¥400,000、Indirect Cost: ¥120,000)
Fiscal Year 2018: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
Fiscal Year 2017: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
Keywordsneutron / radiation field / secondary neutron / Monte Carlo / Bonner sphere system / WENDI-II / 放射線 / 炭素線治療 / 二次中性子 / 晩発性障害 / 照射場 / モンテカルロシミュレーション / エネルギースペクトル / 線量 / 晩発性影響 / 粒子線
Outline of Final Research Achievements

This study focused on the secondary neutrons that cause medical exposure of patients received carbon ion radiotherapy. In particular, in order to realize biological experiments that are essential for establishing a model for predicting secondary cancer risk, we aimed to perform conceptual design including the feasibility study and its experimental verification of a radiation field with a variable neutron energy spectrum.
Our simulation study showed that it is feasible to construct a radiation field that simulates different energy spectra depending on the position in the treatment room for carbon ion radiotherapy without using large-scale and complicated irradiation devices. Moreover, the validity of the simulations was shown by the experimental verification.

Academic Significance and Societal Importance of the Research Achievements

中性子による生物影響は中性子エネルギーに大きく依存するため非常に複雑である。本研究成果により今後、炭素線治療における二次中性子による生物影響を明らかにするための実験を実現する照射場を構築できることが明らかになった。本研究では炭素線治療をターゲットとして研究を進めたが、同じ手法を用いることで他への応用も期待できる。
また、国内では、MeVからGeVオーダーに及ぶエネルギーの高い中性子について照射場や校正場が整備されておらず、この研究成果を用いて高エネルギー中性子に対する照射場、校正場を構築することにより、検出器開発研究等の様々な物理研究の発展を促進することが期待できる。

Report

(4 results)
  • 2019 Annual Research Report   Final Research Report ( PDF )
  • 2018 Research-status Report
  • 2017 Research-status Report
  • Research Products

    (4 results)

All 2020 2019 2018

All Journal Article (1 results) (of which Peer Reviewed: 1 results,  Open Access: 1 results) Presentation (3 results) (of which Int'l Joint Research: 2 results)

  • [Journal Article] Monte Carlo study toward the development of a radiation field to simulate secondary neutrons produced in carbon-ion radiotherapy2020

    • Author(s)
      Yonai Shunsuke、Matsumoto Shinnosuke
    • Journal Title

      Radiation Physics and Chemistry

      Volume: 172 Pages: 108787-108787

    • DOI

      10.1016/j.radphyschem.2020.108787

    • Related Report
      2019 Annual Research Report
    • Peer Reviewed / Open Access
  • [Presentation] Feasibility study on the development of neutron field simulating neutron energy spectra in the CIRT treatment room2019

    • Author(s)
      米内俊祐
    • Organizer
      第118回日本医学物理学会学術大会
    • Related Report
      2019 Annual Research Report
  • [Presentation] Monte Carlo study for development of a radiation field simulating secondary neutrons produced in carbon-ion radiotherapy2019

    • Author(s)
      Shunsuke Yonai
    • Organizer
      3rd International Conference on Dosimetry and Applications
    • Related Report
      2019 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Conceptual design of reference radiation field simulating secondary neutrons during carbon-ion radiotherapy2018

    • Author(s)
      Shunsuke Yonai
    • Organizer
      World Congress on Medical Physics & Biomedical Engineering
    • Related Report
      2018 Research-status Report
    • Int'l Joint Research

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Published: 2017-04-28   Modified: 2021-02-19  

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