| Project/Area Number |
17K18378
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Multi-year Fund |
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| Research Field |
Medical Physics and Radiological Technology
Medical systems
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| Research Institution | National Institutes for Quantum and Radiological Science and Technology |
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Principal Investigator |
Takyu Sodai 国立研究開発法人量子科学技術研究開発機構, 放射線医学総合研究所 先進核医学基盤研究部, 博士研究員(任常) (60796473)
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| Project Period (FY) |
2017-04-01 – 2020-03-31
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| Project Status |
Completed (Fiscal Year 2019)
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| Budget Amount *help |
¥4,290,000 (Direct Cost: ¥3,300,000、Indirect Cost: ¥990,000)
Fiscal Year 2018: ¥2,210,000 (Direct Cost: ¥1,700,000、Indirect Cost: ¥510,000)
Fiscal Year 2017: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
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| Keywords | 放射線検出器 / PET / DOI / TOF / 放射線 |
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| Outline of Final Research Achievements |
Positron emission tomography (PET), which is a powerful imaging modality used for clinical and research purposes, has not fully utilized its potential performance in terms of spatial resolution and sensitivity. Therefore, in this study, we developed a next-generation practical PET detector with time-of-flight (TOF) and depth-of-interaction (DOI) detection capability. The developed single-end readout detector showed around 5 mm DOI resolution and less than 500 ps TOF resolution. Also, the developed dual-end readout detector showed a less than 4 mm DOI resolution and less than 300 ps TOF resolution.
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| Academic Significance and Societal Importance of the Research Achievements |
PETの診断精度向上のためには、現状4-5mm 程度の解像度と5%以下の装置感度について、共に改善を図る必要がある。また、TOF 計測とDOI計測の両立が可能なPET 用検出器は従来技術ではまだ実用化されていない。本研究成果により、上記の解像度と感度を超えるPET装置の開発が可能となり、がんやアルツハイマー病の早期診断において、より早期発見が可能な短時間・低被ばく・低コストなPET 検査の実現が促進されると期待される。
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