| Budget Amount *help |
¥6,500,000 (Direct Cost: ¥5,000,000、Indirect Cost: ¥1,500,000)
Fiscal Year 2019: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
Fiscal Year 2018: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
Fiscal Year 2017: ¥2,600,000 (Direct Cost: ¥2,000,000、Indirect Cost: ¥600,000)
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| Outline of Final Research Achievements |
This study focused on Shigella, which is one of the most significant cause of health hazards in the world among waterborne pathogenic bacteria, and explored virulent bacteriophages (phages) infecting Shigella followed by characterization of the isolated phage strains. Genomic characterization based on full-genome sequence information was performed for a phage strain isolated from municipal wastewater. The result of genomic analysis showed that the isolated phage possessed 168-kb double-stranded linear DNA as a genome. The full-genome sequence was compared with phage genome information deposited in the database, which revealed that the isolated phage is a previously unknown phage belonging to the family Myoviridae. This study provides novel information on bacteriophages infecting Shigella.
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