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Research for the development of guidelines for light environments at night considering high circadian photosensitivity in children

Research Project

Project/Area Number 17K18926
Research Category

Grant-in-Aid for Challenging Research (Exploratory)

Allocation TypeMulti-year Fund
Research Field Architecture, Building engineering, and related fields
Research InstitutionKyushu University

Principal Investigator

Higuchi Shigekazu  九州大学, 芸術工学研究院, 教授 (00292376)

Co-Investigator(Kenkyū-buntansha) 辻村 誠一  鹿児島大学, 理工学域工学系, 教授 (10381154)
Project Period (FY) 2017-06-30 – 2021-03-31
Project Status Completed (Fiscal Year 2020)
Budget Amount *help
¥6,240,000 (Direct Cost: ¥4,800,000、Indirect Cost: ¥1,440,000)
Fiscal Year 2019: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2018: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
Fiscal Year 2017: ¥2,600,000 (Direct Cost: ¥2,000,000、Indirect Cost: ¥600,000)
Keywords光環境 / 照明 / 子ども / 概日リズム / メラトニン / 視覚作用 / 非視覚作用 / 水晶体 / 照度 / 明るさ / 光 / 睡眠 / 非視覚的作用 / 瞳孔
Outline of Final Research Achievements

High light transmittance of the crystal lens and large pupil diameter are thought to be the cause of the large effect of light at night on circadian rhythms in children. In the present study, to verify these relationships, we first developed a device to measure the light transmittance of the crystal lens in vivo. Next, we found that the ratio of circadian clock photoreception (non-visual photoreception) calculated using light transmittance of the lens and pupil diameter between adults and children was almost the same as the ratio of light exposure-induced melatonin suppression between adults and children. Furthermore, the results of the study on the visual effects of illuminance showed that children had a higher sense of brightness and black visibility than adults even at relatively low illuminance levels (10 lx-100 lx).

Academic Significance and Societal Importance of the Research Achievements

水晶体の光透過率を子どもから大人までin vivoで簡便に測定できるシステムを開発した。これによって、水晶体の年齢差や個人差がどのように視覚または非視覚的な機能に影響しているかを明らかにできる可能性が生まれた。家庭で使用する夜の人工照明でも、子どもの概日システムは影響を受けやすいことが示された。一方で、子どもの場合、比較的低照度でも視覚機能への影響は少ない可能性も示された。本研究より、子どもの概日リズムを考慮した夜の光環境の推奨基準を定める基礎的データを得ることができた。

Report

(5 results)
  • 2020 Annual Research Report   Final Research Report ( PDF )
  • 2019 Research-status Report
  • 2018 Research-status Report
  • 2017 Research-status Report
  • Research Products

    (38 results)

All 2021 2020 2019 2018 2017 Other

All Int'l Joint Research (4 results) Journal Article (8 results) (of which Int'l Joint Research: 1 results,  Peer Reviewed: 5 results,  Open Access: 3 results) Presentation (20 results) (of which Int'l Joint Research: 6 results,  Invited: 9 results) Book (4 results) Patent(Industrial Property Rights) (1 results) Funded Workshop (1 results)

  • [Int'l Joint Research] Singapore Eye Research Institute(シンガポール)

    • Related Report
      2020 Annual Research Report
  • [Int'l Joint Research] Singapore Eye Research Institute(シンガポール)

    • Related Report
      2019 Research-status Report
  • [Int'l Joint Research] Singapore Eye Research Institute(シンガポール)

    • Related Report
      2018 Research-status Report
  • [Int'l Joint Research] シンガポール国立大学(シンガポール)

    • Related Report
      2017 Research-status Report
  • [Journal Article] Crystalline lens transmittance spectra and pupil sizes as factors affecting light‐induced melatonin suppression in children and adults2021

    • Author(s)
      Eto Taisuke、Ohashi Michihiro、Nagata Kotaro、Shin Nakyeong、Motomura Yuki、Higuchi Shigekazu
    • Journal Title

      Ophthalmic and Physiological Optics

      Volume: - Issue: 4 Pages: 900-910

    • DOI

      10.1111/opo.12809

    • Related Report
      2020 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] ipRGCの発見と概日リズム研究の発展2021

    • Author(s)
      江藤太亮、樋口重和
    • Journal Title

      日本色彩学会

      Volume: 45 Pages: 15-18

    • Related Report
      2020 Annual Research Report
  • [Journal Article] A Purkinje image-based system for an assessment of the density and transmittance spectra of the human crystalline lens in vivo2020

    • Author(s)
      Eto Taisuke、Teikari Petteri、Najjar Raymond P.、Nishimura Yuki、Motomura Yuki、Kuze Manami、Higuchi Shigekazu
    • Journal Title

      Scientific Reports

      Volume: 10 Issue: 1

    • DOI

      10.1038/s41598-020-73541-y

    • Related Report
      2020 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Melatonin suppression and sleepiness in children exposed to blue‐enriched white LED lighting at night2018

    • Author(s)
      Lee Sang‐il、Matsumori Kouhei、Nishimura Kana、Nishimura Yuki、Ikeda Yuki、Eto Taisuke、Higuchi Shigekazu
    • Journal Title

      Physiological Reports

      Volume: 6 Issue: 24

    • DOI

      10.14814/phy2.13942

    • NAID

      120006585975

    • Related Report
      2018 Research-status Report
    • Peer Reviewed / Open Access
  • [Journal Article] ADAPTATION TO LIGHT ENVIRONMENT : FROM GENOTYPE TO PHENOTYPE2018

    • Author(s)
      樋口 重和
    • Journal Title

      Japanese Journal of Physiological Anthropology

      Volume: 23 Issue: 4 Pages: 171-174

    • DOI

      10.20718/jjpa.23.4_171

    • NAID

      130007580268

    • ISSN
      1342-3215, 2432-0986
    • Related Report
      2018 Research-status Report
    • Peer Reviewed / Open Access
  • [Journal Article] 睡眠負債を招く夜のブルーライト2018

    • Author(s)
      江藤太亮, 樋口重和
    • Journal Title

      労働と科学

      Volume: 73 Pages: 593-597

    • Related Report
      2018 Research-status Report
  • [Journal Article] 瞳孔の対光反射のスペクトル感度に関する研究:児童と若年成人の比較2018

    • Author(s)
      江藤太亮, 松森孝平, 李相逸, 樋口重和
    • Journal Title

      日本生理人類学雑誌

      Volume: 23

    • NAID

      130007403621

    • Related Report
      2017 Research-status Report
    • Peer Reviewed
  • [Journal Article] 子どもの睡眠問題と光環境2017

    • Author(s)
      樋口重和
    • Journal Title

      睡眠医療

      Volume: 11 Pages: 501-505

    • Related Report
      2017 Research-status Report
  • [Presentation] Effects of age-related alteration in pupil size and ocular lens transmittance on differences between melatonin suppression in primary school children and that in middle-aged adults2020

    • Author(s)
      Eto T,Ohashi M,Nagata K,Nishimura Y,Motomura Y,Higuchi S
    • Organizer
      25th Congress of the European Sleep Research Society
    • Related Report
      2020 Annual Research Report
    • Int'l Joint Research
  • [Presentation] 小学生におけるSocial jatlagと水晶体の混濁度との関連性の関する検討2020

    • Author(s)
      江藤太亮, 永田浩太郎, 大橋路弘, 樋口重和
    • Organizer
      第27回時間生物学会学術大会
    • Related Report
      2020 Annual Research Report
  • [Presentation] 生活環境と睡眠・生体リズムおよび健康の関係2020

    • Author(s)
      樋口重和
    • Organizer
      第54回日本作業療法学会
    • Related Report
      2020 Annual Research Report
    • Invited
  • [Presentation] 水晶体の分光透過率と瞳孔径が夜の光曝露によるメラトニン抑制に及ぼす影響:子どもと大人の比較2020

    • Author(s)
      江藤太亮, 永田浩太郎, 大橋路弘, 樋口重和
    • Organizer
      日本生理人類学会第81回大会
    • Related Report
      2020 Annual Research Report
  • [Presentation] 照度の違いが照明環境に対する主観的評価に与える影響の世代比較2020

    • Author(s)
      永田浩太郎,江藤太亮,樋口重和
    • Organizer
      日本生理人類学会第81回大会
    • Related Report
      2020 Annual Research Report
  • [Presentation] Circadian Responses to Spectrum of Light in Primary School Children2019

    • Author(s)
      Shigekazu Higuchi
    • Organizer
      Sleep 2019
    • Related Report
      2019 Research-status Report
    • Int'l Joint Research / Invited
  • [Presentation] 小児期における概日システムの光感受性について2019

    • Author(s)
      樋口重和
    • Organizer
      日本睡眠学会第44回定期学術集会
    • Related Report
      2019 Research-status Report
    • Invited
  • [Presentation] Relationships between Melatonin Suppression by Light and Circadian Rhythm in Children2019

    • Author(s)
      Shigekazu Higuchi, Taisuke Eto, Michihiro Ohashi, Sang-il Lee, Yuki Nishimura, Shingo Kitamura, Akiko Sshikano, Shingo Noi
    • Organizer
      XVI Congress of the European Biological Rhythms Society
    • Related Report
      2019 Research-status Report
    • Int'l Joint Research
  • [Presentation] Light and Circadian Rhythm in Children2019

    • Author(s)
      Shigekazu Higuchi
    • Organizer
      The 14th International Congress of Physiological Anthropology 2019
    • Related Report
      2019 Research-status Report
    • Int'l Joint Research
  • [Presentation] 夜の光と子どもの睡眠について2019

    • Author(s)
      樋口重和
    • Organizer
      第28回日本睡眠環境学会学術大会
    • Related Report
      2019 Research-status Report
    • Invited
  • [Presentation] 光と睡眠とサーカディアンリズム2019

    • Author(s)
      樋口重和
    • Organizer
      日本化粧品技術者会第282回学術講演会
    • Related Report
      2019 Research-status Report
    • Invited
  • [Presentation] 光環境への適応2019

    • Author(s)
      樋口重和
    • Organizer
      第39回日本看護科学学会学術集会
    • Related Report
      2019 Research-status Report
    • Invited
  • [Presentation] プルキンエ像のコントラストを指標とした水晶体分光透過率の測定システムの検討2019

    • Author(s)
      江藤太亮、樋口重和
    • Organizer
      日本視覚学会2019年冬季大会
    • Related Report
      2018 Research-status Report
  • [Presentation] 個人における時刻合わせ問題:学童期および青年期2018

    • Author(s)
      樋口重和
    • Organizer
      第25回日本時間生物学会学術大会
    • Related Report
      2018 Research-status Report
    • Invited
  • [Presentation] 光と適応2018

    • Author(s)
      樋口重和
    • Organizer
      日本生理人類学会第77回大会
    • Related Report
      2018 Research-status Report
    • Invited
  • [Presentation] 自然環境での光曝露が子どもの瞳孔の対光反射に及ぼす影響2018

    • Author(s)
      江藤太亮、武岡功汰、李相逸、北村真吾、樋口重和
    • Organizer
      日本睡眠学会第43回定期学術集会
    • Related Report
      2018 Research-status Report
  • [Presentation] Comparison of spectral sensitivities of pupil light reflex in children and young adults2018

    • Author(s)
      Taisuke Eto, Kouhei Matsumori, Sang-il Lee, Shigekazu Higuchi
    • Organizer
      Asian Forum on Chronobiology in 2018
    • Related Report
      2018 Research-status Report
    • Int'l Joint Research
  • [Presentation] 子どもの夜の光に対する高い感受性と概日リズム2017

    • Author(s)
      樋口重和
    • Organizer
      第35回日本生理心理学会大会
    • Related Report
      2017 Research-status Report
    • Invited
  • [Presentation] 瞳孔の対光反射のスペクトル感度に関する研究:大人と子どもの比較2017

    • Author(s)
      江藤太亮、松森孝平、李相逸、樋口重和
    • Organizer
      日本生理人類学会第75回大会
    • Related Report
      2017 Research-status Report
  • [Presentation] Entrainment of Circadian Rhythm to Natural Light-Dark Cycle in Children2017

    • Author(s)
      Shigekazu Higuchi, kana Nishimura, Sang-il Lee, Shingo Kitamura
    • Organizer
      2017 SSHB - IAPA Joint Symposium
    • Related Report
      2017 Research-status Report
    • Int'l Joint Research
  • [Book] 睡眠学第二班. 第14章 睡眠環境 14.1光環境(日本睡眠学会)2020

    • Author(s)
      樋口重和
    • Total Pages
      712
    • Publisher
      朝倉書店
    • ISBN
      9784254301205
    • Related Report
      2020 Annual Research Report
  • [Book] 生理人類学-人の理解と日常の課題発見のために-. 第2章3 光への適応2020

    • Author(s)
      樋口重和
    • Total Pages
      260
    • Publisher
      理工図書
    • ISBN
      9784844609025
    • Related Report
      2020 Annual Research Report
  • [Book] 子どもの睡眠ガイドブック2019

    • Author(s)
      駒田陽子、井上雄一、白川修一郎、水野一枝、柴田重信、樋口重和、山仲勇二郎、福田一彦、田中秀樹、田村典久、古谷真樹、加藤稲子、井上雄一、碓氷章、志村哲祥、高江洲義和、岡島義、對木悟、神山潤
    • Total Pages
      184
    • Publisher
      朝倉書店
    • ISBN
      9784254301199
    • Related Report
      2019 Research-status Report
  • [Book] ヒトの概日時計と時間2019

    • Author(s)
      山口大学時間学研究所、時間学の構築編集委員会、明石真、樋口重和、西田昌規、座馬耕一郎、小山恵美、福田一彦、駒田陽子、久保達彦、小柳悟、大戸茂弘
    • Total Pages
      196
    • Publisher
      恒星社厚生閣
    • ISBN
      9784769916321
    • Related Report
      2018 Research-status Report
  • [Patent(Industrial Property Rights)] 水晶体の透過スペクトル推定システム及び水晶体の透過スペクトルの推定方法2020

    • Inventor(s)
      樋口重和、江藤太亮、西村悠貴、他2名
    • Industrial Property Rights Holder
      樋口重和、江藤太亮、西村悠貴、他2名
    • Industrial Property Rights Type
      特許
    • Industrial Property Number
      2020-006376
    • Filing Date
      2020
    • Related Report
      2019 Research-status Report
  • [Funded Workshop] 日本生理人類学会光と生体リズム研究部会2018

    • Related Report
      2018 Research-status Report

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Published: 2017-07-21   Modified: 2022-01-27  

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