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Development of seamless high-speed separation and purification platform of 64Cu

Research Project

Project/Area Number 17K19137
Research Category

Grant-in-Aid for Challenging Research (Exploratory)

Allocation TypeMulti-year Fund
Research Field Inorganic/Coordination chemistry, Analytical chemistry, and related fields
Research InstitutionKochi University

Principal Investigator

Mori Masanobu  高知大学, 教育研究部総合科学系複合領域科学部門, 教授 (70400786)

Co-Investigator(Kenkyū-buntansha) 大平 慎一  熊本大学, 大学院先端科学研究部(理), 准教授 (60547826)
須郷 由美  国立研究開発法人量子科学技術研究開発機構, 高崎量子応用研究所 放射線生物応用研究部, 上席研究員(定常) (90354836)
Project Period (FY) 2017-06-30 – 2020-03-31
Project Status Completed (Fiscal Year 2019)
Budget Amount *help
¥6,240,000 (Direct Cost: ¥4,800,000、Indirect Cost: ¥1,440,000)
Fiscal Year 2019: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2018: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
Fiscal Year 2017: ¥3,120,000 (Direct Cost: ¥2,400,000、Indirect Cost: ¥720,000)
KeywordsRI医療 / 分離精製 / 電気化学 / 放射線医療 / 分離 / 精製 / 放射性同位体 / 電気泳動 / バイオ関連機器 / 分析化学
Outline of Final Research Achievements

In this study, we developed a method for separation and purification of 64Cu, which is a nuclide of a drug in positron emission tomography, without heating by using an electrochemical technique. First, in a cold test using stable isotopes, we optimized the conditions to provide quantitative electrodeposition and desorption of Cu(II) from Ni(II) matrix by a column-type flow electrolysis cell (CFE), and to convert liquid property by electrodialysis ion-extraction devise (EID). Under the optimal conditions, in the hot test using a radioisotope, tracer amount of 64Cu produced from the 64Ni target by the (p,n) reaction could be selectively separated and recovered while controlling the adsorption/desorption potential to CFE. Furthermore, the 64Cu isolated in strong acid by CFE was successfully replaced into the weak acid that can be introduced into drug synthesis or the human body by EID.

Academic Significance and Societal Importance of the Research Achievements

これまでも、ポジトロン断層撮影法(PET)に用いる有効な標識薬剤として、64Cuで標識した低分子化合物からペプチドや抗体など様々な標識薬剤の開発が国内外で精力的に進められている。しかし、既存の64Cuの分離精製法は自動装置化されているものの、原理的には従来法のままであるため、現在も製造に長時間要している。本研究では、加熱を一切行わず、分離精製に試薬を用いず、電気のみで高速・高収率な64Cuの分離精製ができることを証明した。実用化に向けいくつかの課題はあるが、本法がもたらす手技の容易さと分離速度の向上は、企業にて装置化・販売できれば、臨床応用への展開が加速されることが大いに期待できる。

Report

(4 results)
  • 2019 Annual Research Report   Final Research Report ( PDF )
  • 2018 Research-status Report
  • 2017 Research-status Report
  • Research Products

    (61 results)

All 2019 2018 2017

All Journal Article (21 results) (of which Int'l Joint Research: 10 results,  Peer Reviewed: 20 results,  Open Access: 8 results) Presentation (38 results) (of which Int'l Joint Research: 14 results,  Invited: 12 results) Patent(Industrial Property Rights) (2 results)

  • [Journal Article] Utilization of Anion-exchange Guard Column as an Ion Chromatographic Column of Anions Including Application to Simultaneous Separation of Anions and Cations2019

    • Author(s)
      YOSHII Sakura、MORI Masanobu、KOZAKI Daisuke、HOSOKAWA Takayuki、ITABASHI Hideyuki
    • Journal Title

      Analytical Sciences

      Volume: 35 Issue: 10 Pages: 1117-1122

    • DOI

      10.2116/analsci.19P146

    • NAID

      130007726250

    • ISSN
      0910-6340, 1348-2246
    • Year and Date
      2019-10-10
    • Related Report
      2019 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Dynamic Four-step Sequential Extraction Procedure Using a Four-channel Circulating Flow System for Extracting Cd, Cu, Pb, and Zn from Solid Environmental Samples2019

    • Author(s)
      ZHAO Meichao、SHINOZAKI Haruka、ITABASHI Hideyuki、KOZAKI Daisuke、MORI Masanobu
    • Journal Title

      Analytical Sciences

      Volume: 35 Issue: 10 Pages: 1089-1096

    • DOI

      10.2116/analsci.19P077

    • NAID

      130007726169

    • ISSN
      0910-6340, 1348-2246
    • Year and Date
      2019-10-10
    • Related Report
      2019 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Separation of Inorganic Anions by a Diol-modified Silica Stationary Phase with Acidic Eluent2019

    • Author(s)
      吉井 咲夢,小﨑 大輔,細川 尭志,板橋 英之,森 勝伸
    • Journal Title

      BUNSEKI KAGAKU

      Volume: 68 Issue: 3 Pages: 201-206

    • DOI

      10.2116/bunsekikagaku.68.201

    • NAID

      130007623957

    • ISSN
      0525-1931
    • Year and Date
      2019-03-05
    • Related Report
      2018 Research-status Report
    • Peer Reviewed
  • [Journal Article] Universal Detection Methods in Ion Chromatography2019

    • Author(s)
      OHIRA Shin-Ichi、TODA Kei
    • Journal Title

      BUNSEKI KAGAKU

      Volume: 68 Issue: 3 Pages: 153-162

    • DOI

      10.2116/bunsekikagaku.68.153

    • NAID

      130007623962

    • ISSN
      0525-1931
    • Year and Date
      2019-03-05
    • Related Report
      2018 Research-status Report
    • Peer Reviewed / Open Access
  • [Journal Article] Physicomechanical properties and durability of a new lightweight porous mortar utilizing woodchips2019

    • Author(s)
      Kenichiro Nakarai, Yuji Suzuki, Masanobu Mori, Lanh Si Ho, Akira Arai, Yusuke Kobayashi
    • Journal Title

      Journal of Cleaner Production

      Volume: 235 Pages: 158-165

    • DOI

      10.1016/j.jclepro.2019.06.244

    • Related Report
      2019 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Enhanced radiocesium uptake by rice with fermented bark and ammonium salt amendments2019

    • Author(s)
      Sun Xiaotong、Kobayashi Shizusa、Tokue Ai、Itabashi Hideyuki、Mori Masanobu
    • Journal Title

      Journal of Environmental Radioactivity

      Volume: 202 Pages: 59-65

    • DOI

      10.1016/j.jenvrad.2019.02.008

    • Related Report
      2019 Annual Research Report 2018 Research-status Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Simultaneous suppression of magnetic nanoscale powder and fermented bark amendment for arsenic and cadmium uptake by radish sprouts grown in agar medium2019

    • Author(s)
      Xiaotong Sun, Huijiao Mo, Ken-ichi Hatano, Hideyuki Itabashi, Masanobu Mori
    • Journal Title

      Environmental Science and Pollution Research

      Volume: - Issue: 14 Pages: 1-11

    • DOI

      10.1007/s11356-019-04756-4

    • Related Report
      2019 Annual Research Report
    • Peer Reviewed / Int'l Joint Research
  • [Journal Article] Single injection ion-exclusion/cation-exchange chromatography for simultaneous determination of organic/inorganic anions, inorganic cations and ethanol in beer samples2019

    • Author(s)
      Daisuke Kozaki, Souma Tanihata, Atsushi Yamamoto, Nobutake Nakatani, Masanobu Mori, Kazuhiko Tanaka
    • Journal Title

      Food Chemistry

      Volume: 274 Pages: 679-685

    • DOI

      10.1016/j.foodchem.2018.09.027

    • Related Report
      2018 Research-status Report
    • Peer Reviewed
  • [Journal Article] Evaluation of Photocatalytic Abilities by Variation of Conductivity and Dimethyl Sulfoxide: Photocatalytically Active TiO<sub>2</sub>-coated Wire Mesh Prepared <i>via</i> a Double-layer Coating Method2018

    • Author(s)
      Masanobu MORI, Tsuyoshi SUGITA, Kengo FUJII, Taiki YAMAZAKI, Mayu ISAKA, Kentaro KOBAYASHI, Shinji IWAMOTO, Hideyuki Itabashi
    • Journal Title

      Analytical Sciences

      Volume: 34 Issue: 12 Pages: 1449-1453

    • DOI

      10.2116/analsci.18N012

    • NAID

      130007528618

    • ISSN
      0910-6340, 1348-2246
    • Year and Date
      2018-12-10
    • Related Report
      2018 Research-status Report
    • Peer Reviewed
  • [Journal Article] Monitoring of the Palladium Concentration in River Water and Sediment at an Acidic Hot Spring Spa Area in Gunma Prefecture2018

    • Author(s)
      Meichao Zhao, Nobuhiko Wada, Haruka Shinozaki, Noriaki Seko, Masanobu Mori, Hideyuki Itabashi
    • Journal Title

      Analytical Sciences

      Volume: 34 Issue: 12 Pages: 1357-1364

    • DOI

      10.2116/analsci.18P211

    • NAID

      130007528620

    • ISSN
      0910-6340, 1348-2246
    • Year and Date
      2018-12-10
    • Related Report
      2018 Research-status Report
    • Peer Reviewed / Int'l Joint Research
  • [Journal Article] Electrodialytic Matrices Isolation for Determination of Heavy Metals in Soil Extracts by Anodic Stripping Voltammetry2018

    • Author(s)
      OHIRA Shin-Ichi、OKAZAKI Chinatsu、TODA Kei
    • Journal Title

      BUNSEKI KAGAKU

      Volume: 67 Issue: 12 Pages: 761-766

    • DOI

      10.2116/bunsekikagaku.67.761

    • NAID

      130007554783

    • ISSN
      0525-1931
    • Year and Date
      2018-12-05
    • Related Report
      2018 Research-status Report
    • Peer Reviewed / Open Access
  • [Journal Article] Growth reduction of Microcystis aeruginosa by clay ball elution solution2018

    • Author(s)
      Tsukasa Ito, Katsuyuki Okabe, Masanobu Mori
    • Journal Title

      Applied Clay Science

      Volume: 162 Pages: 223-229

    • DOI

      10.1016/j.clay.2018.06.018

    • Related Report
      2018 Research-status Report
    • Peer Reviewed
  • [Journal Article] Universal HPLC Detector for Hydrophilic Organic Compounds by Means of Total Organic Carbon Detection2018

    • Author(s)
      Ohira Shin-Ichi、Kaneda Kyosuke、Matsuzaki Toru、Mori Shuta、Mori Masanobu、Toda Kei
    • Journal Title

      Analytical Chemistry

      Volume: 90 Issue: 11 Pages: 6461-6467

    • DOI

      10.1021/acs.analchem.7b04849

    • Related Report
      2018 Research-status Report
    • Peer Reviewed
  • [Journal Article] Electrodialytic in-line preconcentration for ionic solute analysis2018

    • Author(s)
      Ohira Shin-Ichi、Yamasaki Takayuki、Koda Takumi、Kodama Yuko、Toda Kei
    • Journal Title

      Talanta

      Volume: 180 Pages: 176-181

    • DOI

      10.1016/j.talanta.2017.12.054

    • Related Report
      2018 Research-status Report 2017 Research-status Report
    • Peer Reviewed
  • [Journal Article] Ultra-sensitive Trace-Water Optical Sensor with <i>In situ</i>- synthesized Metal&ndash;Organic Framework in Glass Paper2018

    • Author(s)
      Shin-Ichi OHIRA, Nao NAKAMURA, Masaaki ENDO, Yusuke MIKI, Yasuo HIROSE, Kei TODA
    • Journal Title

      Analytical Sciences

      Volume: 34 Issue: 4 Pages: 495-500

    • DOI

      10.2116/analsci.17P453

    • NAID

      130006682640

    • ISSN
      0910-6340, 1348-2246
    • Related Report
      2018 Research-status Report
    • Peer Reviewed
  • [Journal Article] Enhanced aqueous adsorption and photodecomposition of anionic organic target by amino group-modified TiO 2 as anionic adsorptive photocatalyst2018

    • Author(s)
      Sugita Tsuyoshi、Kobayashi Ken-ichi、Kobayashi Kentaro、Yamazaki Taiki、Fujii Kengo、Itabashi Hideyuki、Mori Masanobu
    • Journal Title

      Journal of Photochemistry and Photobiology A: Chemistry

      Volume: 356 Pages: 71-80

    • DOI

      10.1016/j.jphotochem.2017.12.025

    • Related Report
      2017 Research-status Report
    • Peer Reviewed / Int'l Joint Research
  • [Journal Article] Radiocesium dynamics in the aquatic ecosystem of Lake Onuma on Mt. Akagi following the Fukushima Dai-ichi Nuclear Power Plant accident2018

    • Author(s)
      Kyuma Suzuki, Shun Watanabe, Yumi Yuasa, Yasunori Yamashita, Hajime Arai, Hideki Tanaka, Toshihiro Kuge, Masanobu Mori, Kin-ichi Tsunoda, Seiichi Nohara, Yuichi Iwasaki, Yoshitaka Minai, Yukiko Okada, Seiya Nagao
    • Journal Title

      Science of the Total Environment

      Volume: 622-623 Pages: 1153-1164

    • DOI

      10.1016/j.scitotenv.2017.12.017

    • Related Report
      2017 Research-status Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Application of 67Cu Produced with Accelerator Neutrons to the Biodistribution Study2018

    • Author(s)
      Y. Sugo, K. Hashimoto, M. Kawabata, H. Saeki, K. Tsukada, Y. Hatsukawa, and Y. Nagai
    • Journal Title

      QST Takasaki Annual Report 2016

      Volume: QST-M-8 Pages: 123-123

    • Related Report
      2017 Research-status Report
  • [Journal Article] Radioactive Cesium Precipitated in Lake Onuma of Mt. Akagi Emitted by the Fukushima Daiichi Nuclear Power Plant Accident2017

    • Author(s)
      相澤 省一, 森 勝伸, 小池 優子, 角田 欣一
    • Journal Title

      BUNSEKI KAGAKU

      Volume: 66 Issue: 4 Pages: 271-279

    • DOI

      10.2116/bunsekikagaku.66.271

    • NAID

      130006846988

    • ISSN
      0525-1931
    • Related Report
      2017 Research-status Report
    • Peer Reviewed / Int'l Joint Research
  • [Journal Article] Admittance Scanning for Whole Column Detection2017

    • Author(s)
      Stamos Brian N.、Dasgupta Purnendu K、Ohira Shin-Ichi
    • Journal Title

      Analytical Chemistry

      Volume: 89 Issue: 13 Pages: 7203-7209

    • DOI

      10.1021/acs.analchem.7b01412

    • Related Report
      2017 Research-status Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Review: Speciation Analysis of Chromium Oxidation States by Flow Injection Analysis2017

    • Author(s)
      Ohira Shin-Ichi、Nugraha, Willy Chaya、Toda Kei
    • Journal Title

      Journal of Flow Injection Analysis

      Volume: 34 Pages: 5-10

    • Related Report
      2017 Research-status Report
    • Peer Reviewed
  • [Presentation] PET診断用核種Cu-64の電気化学的分離2019

    • Author(s)
      須郷由美,山崎直亨,宮地 凌摩,丸山洋平,大平慎一,森勝伸,石岡典子
    • Organizer
      QST高崎サイエンスフェスタ2019
    • Related Report
      2019 Annual Research Report
  • [Presentation] 電気化学的手法を用いた医療用放射性銅の分離精製2019

    • Author(s)
      森 勝伸,山崎直亨,須郷由美,大平慎一,宮地凌摩,戸田 敬,石岡典子,渡辺茂樹
    • Organizer
      日本分析化学会第79回分析化学討論会
    • Related Report
      2019 Annual Research Report
    • Invited
  • [Presentation] 電気透析型イオン抽出デバイスを用いる有機ヒ素及び無機ヒ素の分離2019

    • Author(s)
      丸山洋平,大平慎一,小﨑大輔,森 勝伸
    • Organizer
      日本分析化学会第79回分析化学討論会
    • Related Report
      2019 Annual Research Report
  • [Presentation] 超微量放射性金属のインラインカウンターイオン置換2019

    • Author(s)
      宮地凌摩,山崎直亨,須郷由美,石岡典子,森 勝伸,大平慎一,戸田 敬
    • Organizer
      日本分析化学会第79回分析化学討論会
    • Related Report
      2019 Annual Research Report
  • [Presentation] カラム型フロー電解セルを用いた医療用放射性銅の分離2019

    • Author(s)
      丸山洋平,須郷由美,大平慎一,山崎直亨,宮地凌摩,戸田 敬,石岡典子,渡辺茂樹,森勝伸
    • Organizer
      日本分析化学会第68年会
    • Related Report
      2019 Annual Research Report
  • [Presentation] PET検査薬剤合成のための放射性同位体金属イオンのハンドリング2019

    • Author(s)
      宮地凌摩,丸山洋平,須郷由美,石岡典子,森 勝伸,大平慎一,戸田 敬
    • Organizer
      日本分析化学会第68年会
    • Related Report
      2019 Annual Research Report
  • [Presentation] 電気透析による放射性金属イオンの抽出とカウンターイオンの置換2019

    • Author(s)
      大平慎一,宮地凌,丸山洋平,須郷由美,石岡典子,森 勝伸,戸田 敬
    • Organizer
      第38回溶媒抽出討論会
    • Related Report
      2019 Annual Research Report
    • Invited
  • [Presentation] Miniaturized cross flow electrodialytic device for flow injection analysis and post-column enhancement on an ion chromatography2019

    • Author(s)
      Shin-Ichi Ohira
    • Organizer
      International symposium on miniaturized systems for chemical separation and analysis
    • Related Report
      2019 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Ion chromatographic evaluation system with a flow-type photocatalyst reactor for performance of the photocatalyst-modified substrates in the aqueous phase2019

    • Author(s)
      Masanobu Mori
    • Organizer
      2019Asia-Pacific Symposium on Iin Analysis (2019 APIA)
    • Related Report
      2019 Annual Research Report
    • Int'l Joint Research
  • [Presentation] 分離科学を応用した化学研究2018

    • Author(s)
      森 勝伸
    • Organizer
      基礎科学招待セミナー/国立研究開発法人日本原子力研究開発機構
    • Related Report
      2018 Research-status Report
    • Invited
  • [Presentation] 分析化学を医療と環境にどのように生かしてきたか2018

    • Author(s)
      森 勝伸
    • Organizer
      平成30年度第10回高知県産学官民連携セミナー,
    • Related Report
      2018 Research-status Report
    • Invited
  • [Presentation] EXAFS analysis of cesium in the sediment at the Lake Akagi Onuma2018

    • Author(s)
      Masanobu Mori
    • Organizer
      The 17 international Conference on X-ray Absorption Fine Structure in Krakow, Poland
    • Related Report
      2018 Research-status Report
    • Int'l Joint Research
  • [Presentation] Separation of Arsenite and Arsenate by Elactrodialytic Ion Isolation Divice2018

    • Author(s)
      Masanobu Mori, Daisuke kozaki, Yo-hei maruyama, Shin-ichi Ohira
    • Organizer
      2018 CJK Symposium on Analytical Chemistry
    • Related Report
      2018 Research-status Report
    • Int'l Joint Research
  • [Presentation] 陰イオン吸着性光触媒の合成とクロマトグラフィーを用いた水質浄化性能評価2018

    • Author(s)
      山崎太樹,小林健太朗,井坂茉由,杉田 剛,森 勝伸,板橋英之
    • Organizer
      日本分析化学会第67年会
    • Related Report
      2018 Research-status Report
  • [Presentation] 光触媒の水質浄化性能試験に関わる流れ分析の利用2018

    • Author(s)
      森 勝伸,杉田 剛
    • Organizer
      日本分析化学会第67年会
    • Related Report
      2018 Research-status Report
  • [Presentation] pH Linear Gradient Generation by Miniaturized Electro-dialysis Device for Chromatographic Separation2018

    • Author(s)
      Bhakti Dwi Yoga, Shin-Ichi Ohira, Kei Toda
    • Organizer
      Asianalysis XIV
    • Related Report
      2018 Research-status Report
    • Int'l Joint Research
  • [Presentation] 電気透析による緩衝溶液の生成とpHのフィードバック制御2018

    • Author(s)
      大平慎一,Bhakti Dwi Yoga,森 秀太,伊藤貴啓,戸田 敬
    • Organizer
      第78回分析化学討論会
    • Related Report
      2018 Research-status Report
  • [Presentation] 標準物質フリーなHPLCの検出システム2018

    • Author(s)
      大平慎一
    • Organizer
      第31回バイオメディカル分析科学シンポジウム
    • Related Report
      2018 Research-status Report
    • Invited
  • [Presentation] 電場と膜透過による光学分割の基礎検討2018

    • Author(s)
      堀内一希,大平慎一,戸田 敬
    • Organizer
      日本分析化学会第67年会
    • Related Report
      2018 Research-status Report
  • [Presentation] Sample pretreatment and separation of ionic solutes by means of electrodialysis2018

    • Author(s)
      Shin-Ichi Ohira
    • Organizer
      3rd International Symposium on Green Technology for Value Chains (GreenVC 2018)
    • Related Report
      2018 Research-status Report
    • Int'l Joint Research / Invited
  • [Presentation] カラム型フロー電解セル-電気透析型イオン抽出デバイスを用いたCu(II)の分離・精製2018

    • Author(s)
      山崎直亨, 森勝伸, 大平慎一, 佐柄克哉, 板橋英之, 須郷由美, 渡辺茂樹, 石岡典子
    • Organizer
      第78回 分析化学討論会
    • Related Report
      2018 Research-status Report
  • [Presentation] PET薬剤に用いるCu-64の新規分離精製方法の開発2018

    • Author(s)
      山崎直亨,須郷由美,大平慎一,板橋英之,石岡典子,森勝伸
    • Organizer
      第35回イオンクロマトグラフィー討論会
    • Related Report
      2018 Research-status Report
  • [Presentation] がん診断用Cu-64の新規分離精製法の開発2018

    • Author(s)
      山崎直亨,須郷由美,大平慎一,板橋英之,石岡典子,森勝伸
    • Organizer
      日本化学会関東支部群馬地区研究交流発表会
    • Related Report
      2018 Research-status Report
  • [Presentation] Speciation of inorganic arsenic by an electrodialytic ion isolation devise2017

    • Author(s)
      Katusya Sagara, Masanobu Mori, Shin-ichi Ohira, Hideyuki Itabashi
    • Organizer
      The 9th Asia-Pacific Symposium on Ion Analysis, Shaoxing, China
    • Related Report
      2017 Research-status Report
    • Int'l Joint Research
  • [Presentation] Speciation of palladium in river water and sediment samples in Kusatsu Hot Spring Area and Shinaki Dam-Lake in Gunma Prefercturer of Japan using sequential extraction2017

    • Author(s)
      Meichao Zhao, Nobuhiko Wada, Haruka Shinozaki, Noriaki Seko, Masanobu Mori, Hideyuki Itabashi
    • Organizer
      The 9th Asia-Pacific Symposium on Ion Analysis, Shaoxing, China
    • Related Report
      2017 Research-status Report
    • Int'l Joint Research
  • [Presentation] Suppression of inorganic arsenic uptake into radish by a mixture of magnetic nanoscale powder and fermented bark amendment2017

    • Author(s)
      Xiaotong Sun, Huijiao Mo, Ken-ichi Hatano, Hideyuki Itabashi, Masanobu Mori
    • Organizer
      The 9th Asia-Pacific Symposium on Ion Analysis, Shaoxing, China
    • Related Report
      2017 Research-status Report
    • Int'l Joint Research
  • [Presentation] Ion chromatography of anions and cations by a series connection of anion-exchange and cation-exchange columns with acidic eluent2017

    • Author(s)
      Sakura Yoshii, Masanobu Mori, Hideyuki Itabashi
    • Organizer
      The 9th Asia-Pacific Symposium on Ion Analysis, Shaoxing, China
    • Related Report
      2017 Research-status Report
    • Int'l Joint Research
  • [Presentation] 分離科学に関するこれまでの歩み2017

    • Author(s)
      森 勝伸
    • Organizer
      平成29年度高知分析技術懇談会
    • Related Report
      2017 Research-status Report
    • Invited
  • [Presentation] Ion-exclusion chromatography of silicate and borate ions with an electro dialytic salt remover2017

    • Author(s)
      Masanobu Mori, Katusya Sagara, Shin-ichi Ohira
    • Organizer
      The 9th Asia-Pacific Symposium on Ion Analysis, Shaoxing, China
    • Related Report
      2017 Research-status Report
    • Int'l Joint Research / Invited
  • [Presentation] ジルコニア固定相を用いるイオンクロマトグラフィー2017

    • Author(s)
      森 勝伸
    • Organizer
      日本分析化学第66年会
    • Related Report
      2017 Research-status Report
    • Invited
  • [Presentation] Analysis of weak acid by combination of an electrodialytic salt removal and ion-exclusion chromatography with corona charged aerosol detection2017

    • Author(s)
      Masanobu Mori
    • Organizer
      2017 Asia / CJK symposium on Analytical Sciences, Tokyo
    • Related Report
      2017 Research-status Report
    • Int'l Joint Research / Invited
  • [Presentation] 標準物質フリーなユニバーサル検出器とその応用2017

    • Author(s)
      大平慎一,金田恭介,戸田 敬
    • Organizer
      第77回分析化学討論会
    • Related Report
      2017 Research-status Report
  • [Presentation] Quantification System without Standard Materials for High Performance Liquid Chromatography (HPLC)2017

    • Author(s)
      大平慎一
    • Organizer
      第23回日本化学会九州支部・韓国化学会釜山支部合同セミナー
    • Related Report
      2017 Research-status Report
    • Int'l Joint Research / Invited
  • [Presentation] 電場による泳動と膜透過による分離手法の展開2017

    • Author(s)
      大平慎一,Willy Cahya Nugraha,戸田 敬
    • Organizer
      日本分析化学会第66年会
    • Related Report
      2017 Research-status Report
  • [Presentation] Calibration free detection system for HPLC2017

    • Author(s)
      Shin-Ichi Ohira, Kyosuke Kaneda, Kei Toda
    • Organizer
      Asia/CJK symposium on analytical science 2017
    • Related Report
      2017 Research-status Report
    • Int'l Joint Research
  • [Presentation] ダイナミックな相間移動による前処理・分離・検出2017

    • Author(s)
      大平慎一
    • Organizer
      徳島大学薬学部 第5回Brightシンポジウム
    • Related Report
      2017 Research-status Report
    • Invited
  • [Presentation] 64/67Cuイオンのがん診断/治療用薬剤としての有用性の検討2017

    • Author(s)
      須郷由美,大島康宏,山口藍子,花岡宏史,塚田和明,橋本和幸,川端方子,佐伯秀也,永井泰樹,石岡典子
    • Organizer
      第1回日本核医学会分科会 放射性薬品科学研究会/第17回放射性医薬品・画像診断薬研究会
    • Related Report
      2017 Research-status Report
  • [Presentation] Cu-64イオンによるがんのPETイメージング2017

    • Author(s)
      須郷由美、大島康宏、山口藍子、花岡宏史、石岡典子
    • Organizer
      第5回メタロミクス研究フォーラム
    • Related Report
      2017 Research-status Report
  • [Patent(Industrial Property Rights)] 分離装置,分離方法,RI分離精製システムおよびRI分離精製方法2018

    • Inventor(s)
      森 勝伸,大平慎一,戸田 敬,須郷由美,渡辺茂樹,石岡典子
    • Industrial Property Rights Holder
      森 勝伸,大平慎一,戸田 敬,須郷由美,渡辺茂樹,石岡典子
    • Industrial Property Rights Type
      特許
    • Industrial Property Number
      2018-080635
    • Filing Date
      2018
    • Related Report
      2018 Research-status Report
  • [Patent(Industrial Property Rights)] 分離装置、分離方法、RI分離精製システムおよびRI分離精製方法2018

    • Inventor(s)
      森 勝伸、大平慎一、戸田 敬、須郷由美、渡辺茂樹、石岡典子
    • Industrial Property Rights Holder
      高知大学、熊本大学、国立研究開発法人量子科学技術研究開発機構
    • Industrial Property Rights Type
      特許
    • Industrial Property Number
      2018-080635
    • Filing Date
      2018
    • Acquisition Date
      2018
    • Related Report
      2017 Research-status Report

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Published: 2017-07-21   Modified: 2021-02-19  

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