| Project/Area Number |
17K19364
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| Research Category |
Grant-in-Aid for Challenging Research (Exploratory)
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| Allocation Type | Multi-year Fund |
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| Research Field |
Molecular and Genome biology and related fields
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| Research Institution | Institute of Physical and Chemical Research |
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Principal Investigator |
Shiroguchi Katsuyuki 国立研究開発法人理化学研究所, 生命機能科学研究センター, ユニットリーダー (00454059)
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| Project Period (FY) |
2017-06-30 – 2019-03-31
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| Project Status |
Completed (Fiscal Year 2018)
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| Budget Amount *help |
¥6,370,000 (Direct Cost: ¥4,900,000、Indirect Cost: ¥1,470,000)
Fiscal Year 2018: ¥3,120,000 (Direct Cost: ¥2,400,000、Indirect Cost: ¥720,000)
Fiscal Year 2017: ¥3,250,000 (Direct Cost: ¥2,500,000、Indirect Cost: ¥750,000)
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| Keywords | 細菌叢 / 定量解析 / 腸内細菌 / シークエンシング / 菌叢 / ネットワーク / 定量計測 |
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| Outline of Final Research Achievements |
Human being lives with about 100 trillion bacteria in/on one’s body. It is well known that the commensal bacteria in the gut affect one’s health, and relationship between the bacteria and human health has been well studied. In this study, we tried to analyze relationship between bacteria which may make distribution (i.e., species and number) of bacteria. Using our own developed method, we measured species and the number of each bacteria in different positions. Some tendencies on the position dependent amount are similar among some bacteria but not others, which may be due to the bacteria interaction.
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| Academic Significance and Societal Importance of the Research Achievements |
腸内の細菌叢のバランス（細菌の種類と数）がヒトの健康に影響を与えていることが分かっている。したがって、このバランスをコントロールすることは、健康を維持するために、もしくは病気を治すために役に立つ可能性がある。本研究において、このバランスを作り出す細菌同士の関係の一部が解析されていることは、バランスのコントロールへ向けた１つの知見を与えることになる。
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