| Budget Amount *help |
¥6,240,000 (Direct Cost: ¥4,800,000、Indirect Cost: ¥1,440,000)
Fiscal Year 2019: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
Fiscal Year 2018: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Fiscal Year 2017: ¥2,600,000 (Direct Cost: ¥2,000,000、Indirect Cost: ¥600,000)
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| Outline of Final Research Achievements |
The minimal mycoplasma has been created from wild type Mycoplasma cells using synthetic biology approaches. Since the minimal cells lack a lot of genes related to cell division and cell cytoskeleton, they could not control cell size, thus they produces a lot of giant and tiny cells during growth. We observed that small cells existed in the large minimal cells, and it was thought to be “cell in cell” or an endosymbiosis of bacteria. In early life, endosymbiosis was thought to be important and frequently happened. For example, Eukaryote was suggested to be derived from endosymbiosis of Archaea and Bacteria. We would suggest the minimal cell as a model cell of the early life.
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