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Evolutionary origin of the neural mechanisms underlying sexual isolation of Drosophila

Research Project

Project/Area Number 17K19425
Research Category

Grant-in-Aid for Challenging Research (Exploratory)

Allocation TypeMulti-year Fund
Research Field Ecology and Evolution (including anthropology), and related fields
Research InstitutionNagoya University

Principal Investigator

Ishikawa Yuki  名古屋大学, 理学研究科, 講師 (70722940)

Research Collaborator Kamikouchi Azusa  
Project Period (FY) 2017-06-30 – 2019-03-31
Project Status Completed (Fiscal Year 2018)
Budget Amount *help
¥6,370,000 (Direct Cost: ¥4,900,000、Indirect Cost: ¥1,470,000)
Fiscal Year 2018: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2017: ¥5,200,000 (Direct Cost: ¥4,000,000、Indirect Cost: ¥1,200,000)
Keywords配偶者選択 / 生殖隔離 / ショウジョウバエ / フェロモン
Outline of Final Research Achievements

Animals often avoid to mate with heterospecific individuals. To understand the neural mechanism underlying the evolution of this behavioral sexual isolation, we focused on Drosophila species, whose sexual isolation mostly depends to cuticular pheromone. First, we screened and identified the sensory neurons which detect heterospecific pheromone and decreases courtship activity. Our further observation of the downstream neurons of these neurons suggests that the acquisition of neural connection between the sensory neurons and the inhibitory downstream neurons contributes the evolution of sexual isolation via heterospecific pheromones.

Academic Significance and Societal Importance of the Research Achievements

生殖隔離の進化は、種分化や性選択を介して、生物多様性の創出/維持に大きな影響を与える。この神経基盤の理解は、生殖隔離の商事やすさや性選択の遷移しやすさを予測し、多様性の動態を理解する上で不可欠である。本研究の成果として、私たちは「神経接続の獲得/喪失が生殖隔離の進化に寄与する可能性」を見出した。このような神経接続と進化の関係はこれまで明確に指摘されてこなかった。しかし、同じ性質を持ったニューロンから構成される神経回路の機能が、神経接続の変化によって劇的に転換しうることを考えると、このような機構は行動進化をもたらす新しい普遍的なしくみのひとつかもしれない。

Report

(3 results)
  • 2018 Annual Research Report   Final Research Report ( PDF )
  • 2017 Research-status Report
  • Research Products

    (23 results)

All 2019 2018 2017 Other

All Journal Article (2 results) (of which Peer Reviewed: 2 results,  Open Access: 1 results) Presentation (16 results) (of which Int'l Joint Research: 4 results,  Invited: 5 results) Book (1 results) Remarks (4 results)

  • [Journal Article] A Single Male Auditory Response Test to Quantify Auditory Behavioral Responses in Drosophila melanogaster2019

    • Author(s)
      Yuki Ishikawa, Natsuki Okamoto, Yusuke Yoneyama, Naoki Maeda, Azusa Kamikouchi
    • Journal Title

      Journal of Neurogenetics

      Volume: 印刷中 Issue: 2 Pages: 64-74

    • DOI

      10.1080/01677063.2019.1611805

    • Related Report
      2018 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Anatomic and Physiologic Heterogeneity of Subgroup-A Auditory Sensory Neurons in Fruit Flies2017

    • Author(s)
      Ishikawa Yuki、Okamoto Natsuki、Nakamura Mizuki、Kim Hyunsoo、Kamikouchi Azusa
    • Journal Title

      Frontiers in Neural Circuits

      Volume: 11 Pages: 46-46

    • DOI

      10.3389/fncir.2017.00046

    • Related Report
      2017 Research-status Report
    • Peer Reviewed / Open Access
  • [Presentation] 性フェロモンに対する選好性の進化を司る神経基盤2018

    • Author(s)
      Yuki Ishikawa, Naoki Maeda, Azusa Kamikouchi
    • Organizer
      第41回日本神経科学学会
    • Related Report
      2018 Annual Research Report
  • [Presentation] Neural mechanism underlying evolution of mating preference in fruit fly2018

    • Author(s)
      Yuki Ishikawa
    • Organizer
      ICOB&NPAS Joint Seminar
    • Related Report
      2018 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] フェロモン選好性の進化を実現する神経回路の変化2018

    • Author(s)
      石川由希、前田直希、上川内あづさ
    • Organizer
      日本進化学会第20回大会
    • Related Report
      2018 Annual Research Report
  • [Presentation] A neural mechanism underlying rapid evolution of mating preference2018

    • Author(s)
      Yuki Ishikawa
    • Organizer
      Japanese-German Frontiers of Science Symposium
    • Related Report
      2018 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Neural mechanism underlying rapid evolution of sex-pheromone preference2018

    • Author(s)
      Yuki Ishikawa, Naoki Maeda, Azusa Kamikouchi
    • Organizer
      13th Drosophila Research Conference
    • Related Report
      2018 Annual Research Report
  • [Presentation] The neural mechanism underlying evolution of mating preference2018

    • Author(s)
      Yuki Ishikawa, Naoki Maeda, Kaori Mochizuki, Gakutami Nomura, Azusa Kamikouchi, Daisuke Yamamoto
    • Organizer
      第46回内藤コンファレンス
    • Related Report
      2018 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Evolutionary change in a neural network underlying mating preference of fruit fly2018

    • Author(s)
      Yuki Ishikawa
    • Organizer
      首都大学バイオコンファレンス
    • Related Report
      2018 Annual Research Report
    • Invited
  • [Presentation] 近縁種との交配を抑制するフェロモン情報処理の進化2018

    • Author(s)
      石川 由希
    • Organizer
      昆虫脳コネクトーム研究若手研究発表会
    • Related Report
      2018 Annual Research Report
  • [Presentation] 性フェロモンへの好みを決める神経回路の進化2018

    • Author(s)
      石川 由希
    • Organizer
      蚕糸・昆虫機能利用学術講演会
    • Related Report
      2018 Annual Research Report
  • [Presentation] Neural basis underlying evolution of mating preference2018

    • Author(s)
      Yuki Ishikawa
    • Organizer
      Neuro Grobal Focusd symposium "Sex on the brain"
    • Related Report
      2017 Research-status Report
    • Int'l Joint Research / Invited
  • [Presentation] ショウジョウバエの種間交雑を妨げるフェロモン選好性の進化の神経基盤2017

    • Author(s)
      Yuki Ishikawa, Naoki Maeda, Gakutami Nomura, Azusa Kamikouchi, Daisuke Yamamoto
    • Organizer
      Evo-Devo青年の会
    • Related Report
      2017 Research-status Report
  • [Presentation] 配偶者選好性の進化をもたらす神経基盤2017

    • Author(s)
      石川由希
    • Organizer
      生命科学の最前線-独自の視点から挑む多彩な生命現象を体感せよ-
    • Related Report
      2017 Research-status Report
    • Invited
  • [Presentation] フェロモン選好性の進化をもたらす2つの異なる神経機構2017

    • Author(s)
      Yuki Ishikawa, Naoki Maeda, Gakutami Nomura, Azusa Kamikouchi, Daisuke Yamamoto
    • Organizer
      第5回神経回路合同研究会
    • Related Report
      2017 Research-status Report
  • [Presentation] ショウジョウバエのフェロモン選好性の進化をもたらす神経基盤2017

    • Author(s)
      Yuki Ishikawa, Naoki Maeda, Gakutami Nomura, Azusa Kamikouchi, Daisuke Yamamoto
    • Organizer
      第19回日本進化学会
    • Related Report
      2017 Research-status Report
  • [Presentation] 種特異的なフェロモン選好性の進化をもたらす神経基盤2017

    • Author(s)
      Yuki Ishikawa, Azusa Kamikouchi, Daisuke Yamamoto
    • Organizer
      日本生態学会第65回全国大会
    • Related Report
      2017 Research-status Report
  • [Presentation] Neural mechanisms underlying the auditory information processing in the fruit fly2017

    • Author(s)
      Yuki ISHIKAWA, Daichi YAMADA, Natsuki OKAMOTO, Mizuki NAKAMURA, Hyunsoo KIM, Azusa KAMIKOUCHI
    • Organizer
      日本比較生理生化学会第39回大会
    • Related Report
      2017 Research-status Report
    • Invited
  • [Book] 遺伝子から解き明かす脳の不思議な世界「第4章 小型でハイスペックな脳の獲得 |昆虫の脳」2018

    • Author(s)
      (第4章著)上川内あづさ、石川由希/(編著)滋野修一、野村真、村上安則
    • Total Pages
      520
    • Publisher
      一色出版
    • ISBN
      9784909383051
    • Related Report
      2018 Annual Research Report
  • [Remarks]

    • URL

      http://www.bio.nagoya-u.ac.jp/~NC_home/index2.htm

    • Related Report
      2018 Annual Research Report
  • [Remarks]

    • URL

      https://sites.google.com/view/yukiishikawa

    • Related Report
      2018 Annual Research Report
  • [Remarks] 上川内研究室ウェブサイト

    • URL

      http://www.bio.nagoya-u.ac.jp/~NC_home/index2.htm

    • Related Report
      2017 Research-status Report
  • [Remarks] 個人ウェブサイト

    • URL

      https://sites.google.com/site/comicalcomet/

    • Related Report
      2017 Research-status Report

URL: 

Published: 2017-07-21   Modified: 2020-03-30  

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