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Estimated numbers of patients with duplicate diseases of liver disease related to hepatitis B or C virus infection based on reconstructed from medical claims

Research Project

Project/Area Number 17K19817
Research Category

Grant-in-Aid for Challenging Research (Exploratory)

Allocation TypeMulti-year Fund
Research Field Society medicine, Nursing, and related fields
Research InstitutionHiroshima University

Principal Investigator

Ohisa Masayuki  広島大学, 医系科学研究科(医), 助教 (20727250)

Co-Investigator(Kenkyū-buntansha) 杉山 文  広島大学, 医歯薬保健学研究科(医), 助教 (50778280)
田中 純子  広島大学, 医歯薬保健学研究科(医), 教授 (70155266)
Project Period (FY) 2017-06-30 – 2019-03-31
Project Status Completed (Fiscal Year 2018)
Budget Amount *help
¥6,110,000 (Direct Cost: ¥4,700,000、Indirect Cost: ¥1,410,000)
Fiscal Year 2018: ¥2,210,000 (Direct Cost: ¥1,700,000、Indirect Cost: ¥510,000)
Fiscal Year 2017: ¥3,900,000 (Direct Cost: ¥3,000,000、Indirect Cost: ¥900,000)
Keywords肝炎ウイルス / B型肝炎 / C型肝炎 / 重複疾患 / 患者数推計 / 診療報酬記録 / レセプト / 重複疾患患者数推計 / 肝疾患関連患者数 / 有病率 / 社会医学 / 疫学 / 数理疫学
Outline of Final Research Achievements

In order to clarify the distribution and frequency of duplicate diseases of liver disease-related patients derived from hepatitis virus, we analyzed 77, 773, 235 medical claims of 3,462,296 people belonging to the Health Insurance Society in 2014-2016.
The three-year period prevalence during 2014-2016 was 100,000 versus pairs 200.8 for hepatitis B-related disease and 170.6 for hepatitis C-related disease.
The percentage of patients with hepatitis B / C-related disease at age 0-64 who had consulted a medical institution had duplicate diseases was 83.1% respectively.Duplicated Diseases frequently are gastritis, duodenitis, lipid abnormalities, rhinitis, hypertension and the like, and it was clarified that many diseases fall under internal medicine (chronic diseases), otology and medicine (acute diseases).

Academic Significance and Societal Importance of the Research Achievements

肝炎ウイルスの持続感染は肝硬変、肝癌のハイリスク因子である。肝炎は自覚症状が現れにくく、潜在しているキャリア、患者としてすでに治療・入院しているキャリア、(継続的な)受診しないままであるキャリアの社会存在状態別に対策を立てる事が重要である。
キャリアとして掘り起こされたとしても、肝臓内科にかからないキャリアや、他の診療科で見出されたキャリアが肝臓内科に受診されない可能性がある。本解析による重複疾患の頻度・分布のデータはキャリアの掘り起こしのための基礎資料となる。

Report

(3 results)
  • 2018 Annual Research Report   Final Research Report ( PDF )
  • 2017 Research-status Report
  • Research Products

    (8 results)

All 2018 2017

All Journal Article (6 results) (of which Int'l Joint Research: 1 results,  Peer Reviewed: 6 results) Presentation (2 results)

  • [Journal Article] Cost-effectiveness analyses of anti-HCV treatments using QOL scoring among patients with chronic liver disease in the Hiroshima prefecture2018

    • Author(s)
      Kaishima T, Akita T, Ohisa M, Sakamune K, Kurisu A, Sugiyama A, Aikata H, Chayama K, Tanaka J
    • Journal Title

      Hepatology Research

      Volume: 印刷中 Issue: 7 Pages: 509-520

    • DOI

      10.1111/hepr.13053

    • Related Report
      2017 Research-status Report
    • Peer Reviewed
  • [Journal Article] A seroepidemiological survey of the effect of hepatitis B vaccine and hepatitis B and C virus infections among elementary school students in Siem Reap province, Cambodia2018

    • Author(s)
      Fujimoto M, Chuon C, Nagashima S, Yamamoto C, Ko K, Svay S, Hok S, Lim O, Ohisa M, Akita T, Katayama K, Matsuo J, Takahashi K, Tanaka J
    • Journal Title

      Hepatology Research

      Volume: 48(3) Issue: 3

    • DOI

      10.1111/hepr.12941

    • Related Report
      2017 Research-status Report
    • Peer Reviewed / Int'l Joint Research
  • [Journal Article] Incidence and risk factors of colorectal cancer based on 56,324 health checkups: 7 years retrospective cohort study2018

    • Author(s)
      Fujii T, Ohisa M, Sako T, Harakawa T, Sakamune K, Nagashima S, Sugiyama A, Matuura Y, Tanaka J
    • Journal Title

      Journal of Gastroenterology and Hepatology

      Volume: 33(4) Issue: 4 Pages: 855-862

    • DOI

      10.1111/jgh.14020

    • Related Report
      2017 Research-status Report
    • Peer Reviewed
  • [Journal Article] Reduced prevalence of hepatitis B surface antigen positivity among pregnant women born after the national implementation of immunoprophylaxis for babies born to hepatitis B virus-carrier mothers in Japan2017

    • Author(s)
      Sugiyama A, Ohisa M, Nagashima S, Yamamoto C, Channarena C, Fujii T, Akita T, Katayama K, Kudo Y, Tanaka J
    • Journal Title

      Hepatology Research

      Volume: 47(12) Issue: 12 Pages: 1329-1334

    • DOI

      10.1111/hepr.12943

    • Related Report
      2017 Research-status Report
    • Peer Reviewed
  • [Journal Article] Pilot study for hepatitis virus screening among employees and effective approach to encourage screened positive employees to receive medical care in Japan2017

    • Author(s)
      Sugiyama A, Fujii T, Nagashima S, Ohisa M, Yamamoto C, Channarena C, Akita T, Matsuo J, Katayama K, Takahashi K, Tanaka J
    • Journal Title

      Hepatology Research

      Volume: 48(3) Issue: 3

    • DOI

      10.1111/hepr.12986

    • Related Report
      2017 Research-status Report
    • Peer Reviewed
  • [Journal Article] Trends in the total numbers of HBV and HCV carriers in Japan from 2000 to 20112017

    • Author(s)
      Tanaka J, Akita T, Ohisa M, Sakamune K, Ko K, Uchida S, Satake M
    • Journal Title

      Journal of Viral Hepatology

      Volume: 25(4) Issue: 4 Pages: 363-372

    • DOI

      10.1111/jvh.12828

    • Related Report
      2017 Research-status Report
    • Peer Reviewed
  • [Presentation] 診療報酬記録に基づいた肝疾患関連患者の重複疾患数の推計2018

    • Author(s)
      大久真幸、松尾順子、田中純子
    • Organizer
      第54回日本肝臓学会総会
    • Related Report
      2018 Annual Research Report
  • [Presentation] 診療報酬記録に基づいた肝疾患関連患者の重複疾患数の推計2018

    • Author(s)
      大久真幸、松尾順子、杉山文、秋田智之、片山惠子、田中純子
    • Organizer
      第54回日本肝臓学会総会
    • Related Report
      2017 Research-status Report

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Published: 2017-07-21   Modified: 2020-03-30  

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